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Context-Dependent Nature of Destabilizing Mutations on the Stability…
www-jackson.ch.cam.ac.uk/publications/1998/1998_Biochem_Main.pdf17 Sep 2003: This increasedto 0.81 (n ) 24) on inclusion of mutations of partially buried hydrophobic residues. ... 23. Shortle, D., and Meeker, A. K. (1989)Biochemistry 28, 936-944. 24. -
Stimulation of the Weak ATPase Activity of Human Hsp90 by a Client…
www-jackson.ch.cam.ac.uk/publications/2002/2002_jmb.pdf15 Sep 2003: The IC50 is approximately 10 mM (data notshown) similar to that measured for yeast Hsp90.24. ... J. Biol. Chem. 274, 17525-17533. 24. Panaretou, B., Prodromou, C., Roe, S. -
Exploring knotting mechanisms in protein foldingAnna L. Mallam,…
www-jackson.ch.cam.ac.uk/publications/2008/2008_PNAS_YibK_mutants.pdf8 Dec 2008: J Mol Biol346:1409 –1421. 24. Tanford C (1968) Protein denaturation. Part A. ... Theoretical models for the mechanismof denaturation. Adv Protein Chem 24:1–95. 26. -
MR-nsmb1204.indd
www-jackson.ch.cam.ac.uk/publications/2004/2004_NSMB_Hsp90_report.pdf6 Jan 2005: Mol. Biol. Cell 12, 3307–3316. (2001).24. Hossain, M.M. & Nakamoto, H. -
doi:10.1016/j.jmb.2007.06.065
www-jackson.ch.cam.ac.uk/publications/2007/2007_J_mol_biol_Hsp90_inhibition.pdf8 Feb 2008: with a Kd of 29(3) nM, following incubationfor 24 h (Figure 2(d)). ... Kd (nM)4 h. Kd (nM)8 h. Kd (nM)24 h. kon(μM1 s1) koff. -
Local and long-range stability in tandemly arrayedtetratricopeptide…
www-jackson.ch.cam.ac.uk/publications/2005/2005_PNAS_Main_tetratricopeptide.pdf17 Jul 2005: first 24 h, then the number of scans wasdoubled, and data were collected over the next 5– 40 days. ... 1 T kin† T eq.‡. CTPR2 19,860 6,692 50 2.24 0.19 0.35 0.21 2.06 0.18 0.5 0.4CTPR3 35,032 7,601 -
doi:10.1098/rsif.2004.0025
www-jackson.ch.cam.ac.uk/publications/2005/2005_Interface_Marianayagam_ubiquitin.pdf17 Jul 2005: J. Mol. Biol. 307, 17–24. Ceruso, M. A., Amadei, A. & Di Nola, A. -
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www-jackson.ch.cam.ac.uk/publications/2004/2004_Biochemistry_UBQ_core.pdf23 Aug 2004: Wild-type and mutant proteins wereexpressed and purified as described elsewhere (24-25). ... Struct. Biol. 8, 331-333. 24. Finucane, M. D., Tuna, M., Lees, J. -
doi:10.1016/j.bpc.2007.03.011
www-jackson.ch.cam.ac.uk/publications/2007/2007_biophys_chem_UBQ.pdf8 Feb 2008: caused by aggregation of the native state, WT⁎ at 2 μM, pH 7.4and 37 C was equilibrated for 24 h in 300 g/L glucose. ... Side-. chain transfer is not, however, sufficient to overcome theunfavourable transfer of the backbone, as observed with -
doi:10.1098/rsif.2004.0025
www-jackson.ch.cam.ac.uk/publications/2006/2006_Marianayagam_Interface_UBQ.pdf13 Sep 2006: J. Mol. Biol. 307, 17–24. Ceruso, M. A., Amadei, A. & Di Nola, A.
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