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  2. Development of Molecular Imaging and Theranostic Agents for Cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf
    30 Apr 2024: Downloaded: 9:17pm, 25 Apr 2024 Page 5 of 9. subdued behaviour which persists for 24 h and cannot be ameliorated by minor veterinary interventions, will be humanely killed before the
  3. University of Cambridge AWERB Handbook Version 6.6 2nd March ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/02.03.2021_awerb_handbook_6.6_external.pdf
    3 Mar 2021: University of Cambridge AWERB Handbook Version 6.6 2nd March 2021. 0. Advice based on Animals (Scientific Procedures) Act 1986. As reviewed and transposed 1 January 2012 and Amended 1 January 2013. University Biomedical Services. Table of Contents.
  4. AWERB Standing Minutes 24th January 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_240124_redacted.pdf
    30 Apr 2024: Page 1 of 3. Minutes. Date Wednesday, 24/01/2024 Time 1pm. To Standing Committee At Virtual, MS Teams. ... Subject AWERB Standing Committee Our Ref Doc.UBS.AWERB.24.01.2024. In attendance:. Scientists in attendance for 1a) Core, 1b) Core & 1c) Core
  5. Determining mechanisms of tumour development and relapse following…

    https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf
    29 Apr 2024: As the mice are checked daily, at most, a mouse would experience paralysis for no more than 24 hours.
  6. PPL number: | Granted: 19 Nov 19 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_of_transgenic_rodents_for_supply_of_tissues_to_the_client_nts_redacted.pdf
    20 Aug 2021: Theories and ideas can. PPL number: | Granted: 19 Nov 19 | Expires: 19 Nov 24. ... Page 8 of 11. PPL number: | Granted: 19 Nov 19 | Expires: 19 Nov 24.
  7. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_canc_redacted.pdf
    30 Apr 2024: PPL number: | Granted: 03 Feb 22 | Amended: 14 Mar 24 | Expires: 03 Feb 27. ... Ascites may occur. PPL number: | Granted: 03 Feb 22 | Amended: 14 Mar 24 | Expires: 03 Feb 27.
  8. Neuronal circuit mechanisms underlying cognitive memory judgements…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf
    30 Apr 2024: A typical study lasts between 12-24 months during which time a marmoset may receive approx. ... Such effects typically resolve within 2 hours but can extend to approximately 24 hours.
  9. PPL number: | Granted: 25 Mar 21 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/circuit_mechanisms_of_learning_and_memory_in_the_mammalian_brain_nts_expires2026_redacted.pdf
    13 Sep 2021: PPL number: | Granted: 25 Mar 21 | Amended: 24 Aug 21 | Expires: 25 Mar 26. ... Objectives and benefits. PPL number: | Granted: 25 Mar 21 | Amended: 24 Aug 21 | Expires: 25 Mar 26.
  10. PPL number: | Granted: 18 Nov 20 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/papillomavirus_transmission_infection_and_lesion_formation_nts_redacted.pdf
    19 Aug 2021: The PV infection protocol (protocol 6) is estimated to require a maximum of 1000 mice (24 mice per experiment, for 50 experiments) over 5 years.
  11. PPL number: | Granted: 21 Aug 19 | Amended: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_role_of_humoral_immunity_in_tissue-specific_immune_responses_in_health_and_disease_redacted.pdf
    20 Aug 2021: PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24. ... Species- Mouse. 10000 over 5 years. Predicted harms. PPL number: | Granted: 21 Aug 19 | Amended: 25 Nov 20 | Expires: 21 Aug 24.
  12. PPL number: | Granted: 09 Sep 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_integrated_stress_response_in_respiratory_disease_nts_redacted.pdf
    13 Sep 2021: drug administration and will be monitored regularly for signs of adverse effects within 24 hours of administration, e.g. ... For blood sampling, no more than 10% of total blood volume in 24 hours and 15% of total blood volume in any 28 day period.
  13. Neural, physiological and behavioural mechanisms underlying cognition …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf
    30 Apr 2024: A typical study lasts between 12-24 months during which time an animal may receive approx. ... Such effects typically resolve within 3 hours but can extend to approximately 24 hours.
  14. AWERB Standing Minutes 28th February 2024_Redacted

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_280224_redacted.pdf
    30 Apr 2024: 4. Minutes of the AWERB sub-standing committee 10/01/24 The minutes were noted. ... 5. Minutes of the AWERB 3Rs Committee 03/01/24 The minutes were noted.
  15. PPL number: | Granted: 05 May 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/safety_efficacy_and_immunogenicity_of_regenerative_cellular_therapies_redacted.pdf
    18 Jun 2021: In such cases, the animals will be culled if these clinical signs do not respond to treatment (such as high energy and easily digestible diet) and persist for up to 24
  16. Investigating the niche of mucosal parasitic nematodes and their…

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf
    30 Apr 2024: 2) Labouring breathing on days 2-4 of hookworm infection, which resolves in 24 hours.
  17. PPL number: | Granted: 02 Feb 21 | Expires: ...

    https://www.ubs.admin.cam.ac.uk/system/files/public/ageing_and_therapy_in_mouse_models_for_neurodegenerative_diseases_redacted_0.pdf
    18 Jun 2021: Animals undergoing surgical procedures will experience transient discomfort after surgery, however these animals will fully recover in less than 24 hours with no lasting effect on their general well being. ... Mild 70%. Moderate 24%. Severe 6%. PPL number
  18. Environmental and placental contributions to pregnancy and life-long…

    https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf
    29 Apr 2024: Any mouse displaying intermittent hunching or abnormal stance or reduced activity for a period of time not to exceed 24 hours, will be humanely killed. •
  19. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: Samples will be collected after humanely killing mice at different ages from birth and up to 24 months of age.
  20. Concordat on Openness on Animal Research in the UKAnnual ...

    https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf
    15 Nov 2023: Concordat on Openness on Animal Research in the UKAnnual Report 2023. H. Hobson and H. Ramchandani. Contents. Foreword 1. Executive summary 2. Introduction 10. About this report 18. PART 1: PROGRESS IN OPENNESS ON ANIMAL RESEARCH IN THE UK 20.
  21. AWERB Standing Minutes 27th March 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_270324_redacted.pdf
    30 Apr 2024: 3. Minutes of last meeting 28/02/24 The minutes were approved. 4. ... 9. List items of note None Date of next meeting: 24/04/2024.

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