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pnas201213624 132..140
www-vendruscolo.ch.cam.ac.uk/ciryam13pnas.pdf10 Jan 2013: A cross-linking study found that the midpoint of stability of an α-hairpintertiary structure was between 24 and 30 residues in linker length (24). ... into contact, which caninclude tertiary structure formation in the last 2 nm of the exittunnel (24, 32) -
bi5b00345 1..12
www-vendruscolo.ch.cam.ac.uk/pustovalova2015b.pdf28 Nov 2015: The relatively small ΔGDN 2.8 0.1 kcal/molfor the I71V mutant results from a large mutually compensatingenthalpic ΔHDN 24.2 0.1 kcal/mol and an entropic TΔSDN21.4 ... Inparticular, δ2D identified three regions of the D statecorresponding to native -
Solution conditions determine the relative importanceof nucleation…
www-vendruscolo.ch.cam.ac.uk/buell2014pnas.pdf26 Jun 2014: teins, including α-synuclein (23, 24), can grow most efficientlyby the addition of oligomers to the fibril ends. ... Conway KA, Harper JD, Lansbury PT (1998) Accelerated in vitro fibril formation by a mu-. -
The Amyloid-β Pathway in Alzheimer’s Disease
www-vendruscolo.ch.cam.ac.uk/Hampel-2021-Molecular-Psychiatry.pdf28 Sep 2021: 300 different autosomaldominant mutations reported in these genes [23, 24].The locus of the APP gene is on chromosome 21. -
14945019074674 1..31
www-vendruscolo.ch.cam.ac.uk/kitevski-leblanc2017elife.pdf17 Sep 2017: I44δ1. 1.0 0.8 0.61H ppm. 26.0. 24.0. 22.0. 15.0. 13.0. 11.0. ... RNF169]/[ub]. RNF169(UDM2). KD=24 7μM. kON. = 2.3 0.7 x 107 M-1 s-1.
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