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ar5000117 1..9
www-vendruscolo.ch.cam.ac.uk/obrien2014acr.pdf2 Jun 2014: The rate kA,i1 isan important quantity because it defines the average speed atwhich codon i is translated.The other relevant rates are those associated with the process. ... and genomic sequences. This information enables reasonableestimates of kA,i1, kFU -
Kinetic modelling indicates that fast-translating codons can…
www-vendruscolo.ch.cam.ac.uk/obrien2014nc.pdf8 Jan 2014: þXij1. kIU;jkUF;jDj. Yiljþ1. kA;l þ1kA;l þ1 þkIU;l þkUI;l þkUF;lDl. :. ð6Þ. ... determine the derivative in terms of kA,iþ1; weprovide the exact expression in Supplementary Eq. -
Understanding the frustration arising from thecompetition between…
www-vendruscolo.ch.cam.ac.uk/gianni2014pnas.pdf7 Oct 2014: Proc Natl Acad SciUSA 96(26):14854–14859. 18. Scott KA, Randles LG, Clarke J (2004) The folding of spectrin domains II: Phi-valueanalysis of R16. ... Nat Struct Biol 9(3):209–216. 35. Ozkan SB, Bahar I, Dill KA (2001) Transition states and the -
C2PROT070165 536..550
www-vendruscolo.ch.cam.ac.uk/periole2007p.pdf25 Feb 2014: 4Ru. n1,. 227. /22. 22/1. 317. /618. /927. /10. 24/1. 631. ... By contrast, nonnative con-. formations were observed in b1 and in the divergingturn (residues 20–24). -
pone.0087133 1..11
www-vendruscolo.ch.cam.ac.uk/toth2014po.pdf25 Feb 2014: fluctuating structural ensemble [23,24]. Such residual local. structure could provide an opportunity for small molecule. ... mouse microglia were plated in 24-well plates at 16105 cells/well for 1 day. -
pone.0085185 1..8
www-vendruscolo.ch.cam.ac.uk/abeln2014po.pdf18 Jan 2014: 21. Prabhu NV, Sharp Ka (2005) Heat capacity in proteins. Annu Rev Phys Chem. ... 2001) Sequence. complexity of disordered protein. Proteins 42: 38–48.24. Deechongkit S, Nguyen H, Powers ET, Dawson PE, Gruebele M, et al. -
Cyclophilin A catalyzes proline isomerization by anelectrostatic…
www-vendruscolo.ch.cam.ac.uk/camilloni2014pnas.pdf12 Aug 2014: catalysis. Nature 462(7273):669–673.24. Wüthrich K (1989) Protein structure determination in solution by nuclear magnetic. ... J Am Chem Soc 132(4):1220–1221.31. Robustelli P, Stafford KA, Palmer AG, 3rd (2012) Interpreting protein structural dy-. -
Solution conditions determine the relative importanceof nucleation…
www-vendruscolo.ch.cam.ac.uk/buell2014pnas.pdf26 Jun 2014: teins, including α-synuclein (23, 24), can grow most efficientlyby the addition of oligomers to the fibril ends. ... Conway KA, Harper JD, Lansbury PT (1998) Accelerated in vitro fibril formation by a mu-.
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