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ar5000117 1..9
www-vendruscolo.ch.cam.ac.uk/obrien2014acr.pdf2 Jun 2014: The rate kA,i1 isan important quantity because it defines the average speed atwhich codon i is translated.The other relevant rates are those associated with the process. ... and genomic sequences. This information enables reasonableestimates of kA,i1, kFU -
Cooperative Assembly of Hsp70 Subdomain Clusters
www-vendruscolo.ch.cam.ac.uk/wright2018b.pdf23 Sep 2018: Chem. 272, 2951129517.(24) Feil, I. K., Malfois, M., Hendle, J., van Der Zandt, H., andSvergun, D. ... M. (2003) Microfluidic devicesfabricated in poly(dimethylsiloxane) for biological studies. Electro-phoresis 24, 35633576.(34) Herling, T. -
Kinetic modelling indicates that fast-translating codons can…
www-vendruscolo.ch.cam.ac.uk/obrien2014nc.pdf8 Jan 2014: þXij1. kIU;jkUF;jDj. Yiljþ1. kA;l þ1kA;l þ1 þkIU;l þkUI;l þkUF;lDl. :. ð6Þ. ... determine the derivative in terms of kA,iþ1; weprovide the exact expression in Supplementary Eq. -
ja407951x 1..10
www-vendruscolo.ch.cam.ac.uk/biedermann2013jacs.pdf4 Oct 2013: 14,15 Besides, the higher affinity of Phe-(Gly)2(Ka,ternary = 2 10. ... contribution for hostguest binding (Ka up to 106M1, ΔH up to 70 kJ mol1). -
Exploring the role of post‐translational modifications in regulating…
www-vendruscolo.ch.cam.ac.uk/elturk2018ps.pdf23 Sep 2018: of a-synuclein.19,22,24 Second, a central. amyloidogenic region, termed the nonamyloid b com-. ... kona (106 M21 s21) koff. a (1023 s21) Ka (107 M21)b Kd (10. -
pcbi.1002169 1..9
www-vendruscolo.ch.cam.ac.uk/fitzpatrick11pcb.pdf15 Jan 2012: 0.82 kB T) and polar-polar (P-P, 24% of all contacts,21.69 kBT, s.d. ... Biochemistry 24: 1501–1509. 12. Dobson CM (1999) Protein misfolding, evolution and disease. -
JCB: Article The Rockefeller University Press $30.00J. Cell Biol. ...
www-vendruscolo.ch.cam.ac.uk/chambers12jcb.pdf14 Aug 2012: kf(min1) ka(m3(n1)mole(n1)min1) n Aggregation Degradation. ADPr ADPr+ ADPr ADPr+. mol/24 h mol/24 h0.2 5 3 136.6 107.7 314.6 ... The effects of changing the rate of folding (kf) or the terms governing the concentration dependence of aggregation (ka and n) -
The codon information index: a quantitative measure of the…
www-vendruscolo.ch.cam.ac.uk/caniparoli2013jsm.pdf16 Jul 2013: where Ka is the number of codons encoding for the amino acid a, ns,a(ca) is the number of. ... times a spin s is associated to the codon ca of the amino acid a and Ns,a =Ka. -
A PDZ domain recapitulates a unifying mechanism for protein ...
www-vendruscolo.ch.cam.ac.uk/gianni07.pdf21 Dec 2006: The fingerprint of this situation isa scatter in the Brønsted plot, as observed for barnase (24),En-HD (13), and FF domain (25). ... 96:14854 –14859.28. Scott KA, Randles LG, Clarke J (2004) J Mol Biol 344:207–211.29. -
pone.0072286 1..5
www-vendruscolo.ch.cam.ac.uk/waudby2013po.pdf4 Oct 2013: with the increase in the a-helical population in the first 12 N-terminal residues reported from in vitro studies [24] no additional. ... doi:10.1074/jbc.M109541200. 4. Weinreb PH, Zhen W, Poon AW, Conway KA, Lansbury PT (1996) NACP, a.
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