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  2. Biological sequence analysis: Probabilistic models of proteins and…

    https://www.cl.cam.ac.uk/teaching/2324/Bioinfo/papers/RNApredictionDurbin.pdf
    3 Oct 2023: Intuitively, Mi j tells us how much information we get about the identity ofthe residue in one position if we are told the identity of the residue in the otherposition. ... This has the advantage that itmakes no assumptions about Watson–Crick base

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