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Emmanuel Derivery - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/emmanuel-derivery/23 Feb 2024: Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M., Planelles-Herrero, VJ., Chambers, JE., Manton, JD., Baker, D., Derivery, E. ... Watson, J.L., Aich, S., Oller-Salvia, B., Drabek, A.A., Blacklow, S.C., Chin, J., Derivery E. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/221factors. n. He then returned to the LMB in 1970 as a staff scientist – a position he held until his retirement in 2008. ... n. The resulting compensating writhe then facilitates the concerted packing of the parallel stacks into a 2-start helical coil. -
Andrew Travers - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/andrew-travers/14 Mar 2024: After this he took a couple of years out as a post-doc in Jim Watson’s lab at Harvard University where he co-discovered the first of the RNA polymerase ... Proc. Natl. Acad. Sci. USA 109: E49-E50. Sobetzko, P., Glinkowska, M., Travers, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985{"id":1985,"date":"2012-07-18T16:07:14","date_gmt":"2012-07-18T15:07:40","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1985"},"modified":"2021-03-30T15:06:15","modified_gmt":"2021-03-30T14:06:15","slug":"francis-crick-1916-2004 -
Simon Bullock - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/simon-bullock/5 Mar 2024: How is the action of multiple motors bound to a single cargo orchestrated? ... Nat Struct Mol Biol, s41594-024-01212-x. Madan V., Albacete-Albacete L., Jin L., Scaturro P., Watson J.L., Muschalik N., Begum F., Boulanger J., Bauer K., Kiebler M.A., -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697 -
DNA - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/dna/feed/12 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/oneill/publications/Watson, J.L., et al. (2023 ). Macromolecular condensation buffers intracellular water potential.. ... Nat Chem Biol 17(4): 373-374. Stangherlin, A., O'Neill, J.S. (2018). -
James Watson - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/james-watson/feed/12 Jul 2024: ac.uk"MRC Laboratory of Molecular Biology/a./p ... post a href="https://www2.mrc-lmb.cam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a -
The Eagle - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/the-eagle/feed/12 Jul 2024: 01 0000 http://www2.mrc-lmb.cam.ac.uk/wordpress/?post_type=photo_archive&p=2563 pThe post a ... outside-the-eagle/"Jim Watson Outside The Eagle/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular Biology/a./p pThe post -
Francis Crick - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/francis-crick/feed/12 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
LMB Nobel Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry). -
Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/models/feed/12 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: Arka Chakraborty is carrying on structural work on a related complex, ATR/ATRIP. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M., -
How cellular clocks within heart cells coordinate daily cardiac…
https://www2.mrc-lmb.cam.ac.uk/how-cellular-clocks-within-heart-cells-coordinate-daily-cardiac-rhythms/15 Oct 2021: cells make as great a contribution to daily variation in heart rate as signals from the nervous system. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Structure 27(2): 241-252.e3. Buonarati, O.R., Hammes, E.A., Watson, J.F., Greger, I.H., Hell, J.W. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J. ... Frey, A., Listovsky, T., Guilbaud, G., Sarkies, P. and Sale, J.E.† (2014). -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/19717a flat honeycomb structure that can inhibit endocytosis of receptors from the cell surface. ... nnnn. A sheet of proteins (pink and blue) forms a honeycomb-like structure over the surface of a cell. -
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/15
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/152003/a/lilia href="#pub2002"2002/a/lilia href="#pub2000"2000/a/lilia href="#pub1998"1998/a/li/ulh3 id="pub2024"2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Stockwell, I., Watson, ... 241-252.e3/span/lilispan class="pubAuthors"Buonarati, O.R., -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/8612{"id":8612,"date":"2016-03-18T10:46:45","date_gmt":"2016-03-18T10:46:45","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=8612"},"modified":"2024-03-21T17:04:51","modified_gmt":"2024-03-21T17:04:51","slug":"nanostructures-synthetic-genetic-polyme -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20560 -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/groups/murshudov/content/courses/lmb_crystallography_course_2013/lectures/pathologies_and_twinning.pdf11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/21397{"id":21397,"date":"2021-10-15T10:14:15","date_gmt":"2021-10-15T09:14:15","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=21397"},"modified":"2021-10-28T09:57:04","modified_gmt":"2021-10-28T08:57:04","slug":"how-cellular-clocks-within-heart-cel -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/37738It is the hallmark of stem cells, in which one daughter cell specialises to perform a specific function in the organism, while the other becomes another stem cell that keeps the -
Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/30 Mar 2021: He will be best remembered for DNA, whose structure he discovered with Jim Watson in 1953. ... amino acid for another was presumed to reflect the change of a single base in the gene. -
Clathrin-mediated endocytosis: Adaptor appendage domains.…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/Adaptors/Appendages.html26 Sep 2011: This work is still ongoing. These pages are written to accompany a review by Mills et al 2004. ... Gamma-COP appendage (COPI coat subunit). 1 binding site on the platform subdomain (taken from Hoffman et al 2003 and Watson et al 2004). -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/153768{"id":153768,"date":"2023-10-18T16:34:27","date_gmt":"2023-10-18T15:34:27","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=153768"},"modified":"2023-10-18T16:35:03","modified_gmt":"2023-10-18T15:35:03","slug":"new-mechanism-found-that-maintains -
A new 2D protein material for studying receptor endocytosis - MRC…
https://www2.mrc-lmb.cam.ac.uk/a-new-2d-protein-material-for-studying-receptor-endocytosis/6 Jan 2021: Joseph Watson, in Emmanuel’s group, reasoned that such a material could have powerful effects on cells. ... Ben-Sasson, AJ., Watson, JL., Sheffler, W., Johnson, MC., Bittleston, A., Somasundaram, L., Decarreau, J., Jiao, F., Chen, J., Mela, I., Drabek, -
Nanostructures from synthetic genetic polymers - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/nanostructures-synthetic-genetic-polymers/18 Mar 2016: specifically from a series of ‘synthetic genetic polymers’, also known as xeno nucleic acids (XNAs). ... Although distinct from DNA and RNA, the XNAs still carry the bases A, T, C and G, so the standard Watson-Crick base pairing rules still operate -
https://www2.mrc-lmb.cam.ac.uk/groups/oneill/wp-json/wp/v2/pages/9
https://www2.mrc-lmb.cam.ac.uk/groups/oneill/wp-json/wp/v2/pages/9data-id="https://pubmed.ncbi.nlm.nih.gov/?term=O%27NeillJS&sort=pubdate"here/a. ... For a selection of our most recent, see below:/pnnnnh2 class="wp-block-heading"Most recent articles/h2nnnul class="lmbpubmedpapers"lispan class="pubAuthors"Watson, J.L., -
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-json/wp/v2/pages/312 -
New mechanism found that maintains intracellular water balance - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-mechanism-found-that-maintains-intracellular-water-balance/18 Oct 2023: Joseph Watson led the imaging studies and yeast experiments, Estere Seinkmane led proteomic and phosphoproteomic analyses and Christine Styles led the cell viability and cell adaptation experiments. ... Further references. Watson, JL., Seinkmane, E., -
https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15
https://www2.mrc-lmb.cam.ac.uk/groups/shahbazi/wp-json/wp/v2/pages/15content":{"rendered":"h3 2024/h3ul class="lmbpubmedpapers"lispan class="pubAuthors"Sato, N., et al./span span class="pubDate"(2024 )/spanbr /a href="http://www.ncbi.nlm.nih.gov/pubmed/38579720" ... ulh3 2023/h3ul class="lmbpubmedpapers"lispan -
LMB 365 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/news-and-events/lmb-365/21 Jul 2023: Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... This was the LMB’s second Nobel for 1962, Francis Crick and James Watson had already been awarded the Physiology and Medicine Prize for their work on the structure of DNA. -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/%22https:/www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&11 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/58doi: 10.1038/s41594-024-01212-x/span. a href="https://pubmed.ncbi.nlm.nih.gov/38297086/"Pubmed/a/pnpMadan V, Albacete Albacete L, Jin L, Scaturro P, Watson JL, Muschalik ... MAPs, and microtubule ends on directional movement of a localising mRNA./strong -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/16108Molecular Biology (LMB) and AstraZeneca to support a range of pre-clinical research projects. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, -
All publications
https://www2.mrc-lmb.cam.ac.uk/ccsb/publications/all-publications-2/J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S. -
Coot Scripting Interface: c-interface.h File Reference
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h.html24 Aug 2021: if this is not a standard group, then turn the atoms to HETATMs. ... screendump_image (const char filename). dump the current screen image to a file. -
New method to untangle the contribution of signalling pathways…
https://www2.mrc-lmb.cam.ac.uk/new-method-to-untangle-the-contribution-of-signalling-pathways-involved-in-asymmetric-cell-division/28 Sep 2023: In this study, co-led by Joseph Watson and Lara Krüger, the team developed an assay which allows the contribution of each pathway involved in the process to be dissected. ... Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M., -
Chin
https://www2.mrc-lmb.cam.ac.uk/ccsb/category/publications/feed/3 Apr 2024: Biol/em/emstrong 2021/strong 220 (2): e202009063./abr / J. L. Watson, S. Aich, B. ... 284-285/a,a href="http://cen.acs.org/magazine/89/8907.html" target="_blank" rel="noopener noreferrer"emChem. -
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-json/wp/v2/pages/19item fg-type-image fg-idle"figure class="fg-item-inner"a href="https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/398_jake-watson.jpg" ... data-caption-title="Jake Watson" data-attachment-id="102" data-type="image" -
New structures show how auxiliary subunits modulate hippocampal AMPA…
https://www2.mrc-lmb.cam.ac.uk/new-structures-show-how-auxiliary-subunits-modulate-hippocampal-ampa-receptor-neurotransmission/2 Jun 2021: Danyang Zhang, a postdoctoral researcher in Ingo’s group, determined these structures using cryo-EM. ... Zhang, D., Watson, JF., Matthews, PM., Cais, O., Greger, IH. NaturePrevious Insight on Research. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/13500Day 362 of #LMB365 shows the LMB Executive Committee after a recent meeting. ... Protein samples frozen on grids in amorphous ice are placed inside a nanocap. -
Jim Watson Outside The Eagle - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Fjim-watson-outside-the-eagle%2F&format=xmlcam.ac.uk/photo-archive/jim-watson-outside-the-eagle/">Jim Watson Outside The Eagle</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... photo-archive/jim-watson-outside-the-eagle/embed/#?secret=zjOHzjaM8Z" width="600" height="338" -
Reproduction of Watson & Crick DNA Model - MRC Laboratory of…
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fphoto-archive%2Freproduction-of-watson-crick-dna-model%2F&format=xmlcam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/">Reproduction of Watson & Crick DNA Model</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/embed/#?secret=9 -
Pymol guide
https://www2.mrc-lmb.cam.ac.uk/groups/nagai/download/pymolguide.pdf19 Dec 2017: We can see that there are non-Watson-Crick base pairs here, but the cartoon view of the bases doesn’t show the donor and acceptor groups very well. ... To see how the ligand is bound, PyMOL has a really useful tool. -
1962 - Francis Crick & James Watson - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fachievements%2Flmb-nobel-prizes%2F1962-francis-crick-james-watson%2F&format=xmlcam.ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/">1962 – Francis Crick & James Watson</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/e -
The Coot User Manual
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html1 Mar 2021: The Coot User Manual
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