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Emmanuel Derivery - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/emmanuel-derivery/23 Feb 2024: Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M., Planelles-Herrero, VJ., Chambers, JE., Manton, JD., Baker, D., Derivery, E. ... Watson, J.L., Aich, S., Oller-Salvia, B., Drabek, A.A., Blacklow, S.C., Chin, J., Derivery E. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/1985{"id":1985,"date":"2012-07-18T16:07:14","date_gmt":"2012-07-18T15:07:40","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=1985"},"modified":"2021-03-30T15:06:15","modified_gmt":"2021-03-30T14:06:15","slug":"francis-crick-1916-2004 -
Andrew Travers - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/andrew-travers/14 Mar 2024: After this he took a couple of years out as a post-doc in Jim Watson’s lab at Harvard University where he co-discovered the first of the RNA polymerase ... Proc. Natl. Acad. Sci. USA 109: E49-E50. Sobetzko, P., Glinkowska, M., Travers, A. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/20969 -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/6697{"id":6697,"date":"2014-10-02T16:31:05","date_gmt":"2014-10-02T15:31:05","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?page_id=6697"},"modified":"2023-07-21T12:52:04","modified_gmt":"2023-07-21T11:52:04","slug":"nobel-facts","status":"publish"," -
Simon Bullock - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/simon-bullock/5 Mar 2024: How is the action of multiple motors bound to a single cargo orchestrated? ... Nat Struct Mol Biol, s41594-024-01212-x. Madan V., Albacete-Albacete L., Jin L., Scaturro P., Watson J.L., Muschalik N., Begum F., Boulanger J., Bauer K., Kiebler M.A., -
DNA - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/dna/feed/17 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/oneill/publications/Watson, J.L., et al. (2023 ). Macromolecular condensation buffers intracellular water potential.. ... Nat Chem Biol 17(4): 373-374. Stangherlin, A., O'Neill, J.S. (2018). -
Fast Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/fast-facts/21 Jul 2023: Francis Crick and Jim Watson helped unravel the structure of DNA – one of the scientific landmarks of the 20th century – in the MRC Unit. ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), -
James Watson - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/james-watson/feed/17 Jul 2024: ac.uk"MRC Laboratory of Molecular Biology/a./p ... post a href="https://www2.mrc-lmb.cam.ac.uk/photo-archive/reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/32{"id":32,"date":"2012-06-25T09:59:05","date_gmt":"2012-06-25T09:59:05","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=32"},"modified":"2023-07-21T12:49:29","modified_gmt":"2023-07-21T11:49:29","slug":"scientific-models","status" -
The Eagle - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/the-eagle/feed/17 Jul 2024: 01 0000 http://www2.mrc-lmb.cam.ac.uk/wordpress/?post_type=photo_archive&p=2563 pThe post a ... outside-the-eagle/"Jim Watson Outside The Eagle/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular Biology/a./p pThe post -
Francis Crick - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/francis-crick/feed/17 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
Scientific Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/scientific-models/21 Jul 2023: A year later I was able to get Jim Watson’s signature when he stopped by the LMB on a visit.’ Arthur Arnone, 28 October 2003. ... Model built by A.A.Barker. To an original design and specification supplied by Dr H.C.Watson, Laboratory of Molecular -
LMB Nobel Facts - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/achievements/lmb-nobel-prizes/nobel-facts/21 Jul 2023: 1962 - Francis Crick & Jim Watson (Physiology or Medicine). 1958 - Fred Sanger (Chemistry). ... In 1962, the LMB was awarded 2 separate Nobel Prizes: Francis Crick and Jim Watson (Physiology or Medicine), and Max Perutz and John Kendrew (Chemistry). -
Models - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/keywords/models/feed/17 Jul 2024: reproduction-of-watson-crick-dna-model/"Reproduction of Watson & Crick DNA Model/a appeared first on a href="https://www2.mrc-lmb.cam.ac.uk"MRC Laboratory of Molecular ... p pThe post a -
DNA discovery pioneer James Watson pays tribute to colleague Francis…
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fdna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick%2F&format=xmlcam.ac.uk/dna-discovery-pioneer-james-watson-pays-tribute-colleague-francis-crick/">DNA discovery pioneer James Watson pays tribute to colleague Francis Crick</a></blockquote><iframe sandbox="allow-scripts" ... https://www2.mrc-lmb.cam.ac.uk/wordpress/wp- -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/997{"id":997,"date":"2012-07-03T09:13:21","date_gmt":"2012-07-03T09:13:21","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/wordpress/?page_id=997"},"modified":"2023-07-21T12:49:21","modified_gmt":"2023-07-21T11:49:21","slug":"fast-facts","status":"pub -
Francis Crick (1916 - 2004) - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/francis-crick-1916-2004/30 Mar 2021: He will be best remembered for DNA, whose structure he discovered with Jim Watson in 1953. ... amino acid for another was presumed to reflect the change of a single base in the gene. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/jes/publications.html17 Sep 2020: Ho, T.L.F., Guilbaud, G., Blow, J.J., Sale, J.E. and Watson, C.J. ... Frey, A., Listovsky, T., Guilbaud, G., Sarkies, P. and Sale, J.E.† (2014). -
LMB 365 - Day 60 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-60%2F&format=xml1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="G2NErIg1WL"><a ... handful of pseudocoloured hippocampal neurons (brain cells) that have been specifically targeted -
LMB 365 - Day 100 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Flmb-365-day-100%2F&format=xml1.0 MRC Laboratory of Molecular Biology https://www2.mrc-lmb.cam.ac.uk rich 600 338 <blockquote class="wp-embedded-content" data-secret="khP5plNX3G"><a ... By simulating the activity of individual synapses on a neuron, seen as deflections in this image -
Herbert ‘Freddie’ Gutfreund - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/lmb-alumni/alumni/herbert-freddie-gutfreund/18 Nov 2021: Crick, James Watson and Hugh Huxley. ... Memories of a Senior Scientist: I was lucky, I was there at the right time. -
Books - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/books/21 Jul 2023: L. Bragg: A Few Personal Recollections’ by Francis Crick. ‘Bragg’s Foreword to The Double Helix‘ by James Watson. ... Minds that live for science’ James Watson. ‘Ruthless research in a cupboard’ Francis Crick. -
1962 - Francis Crick & James Watson - MRC Laboratory of Molecular …
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fachievements%2Flmb-nobel-prizes%2F1962-francis-crick-james-watson%2F&format=xmlcam.ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/">1962 – Francis Crick & James Watson</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... ac.uk/achievements/lmb-nobel-prizes/1962-francis-crick-james-watson/e -
Moments of Genius: Nobel laureate Venki Ramakrishnan describes how…
https://www2.mrc-lmb.cam.ac.uk/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww2.mrc-lmb.cam.ac.uk%2Fmoments-of-genius-nobel-laureate-venki-ramakrishnan-describes-how-james-watson-discovered-dna-base-pairing%2F&format=xmlbase pairing</a></blockquote><iframe sandbox="allow-scripts" security="restricted" ... 182 100 “Nobel laureate Venki Ramakarishnan describes how James Watson discovered DNA base pairing which showed how the DNA double helix could carry. -
The Coot User Manual
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/web/docs/coot.html1 Mar 2021: The Coot User Manual -
New mechanism found that maintains intracellular water balance - MRC…
https://www2.mrc-lmb.cam.ac.uk/new-mechanism-found-that-maintains-intracellular-water-balance/18 Oct 2023: Joseph Watson led the imaging studies and yeast experiments, Estere Seinkmane led proteomic and phosphoproteomic analyses and Christine Styles led the cell viability and cell adaptation experiments. ... Further references. Watson, JL., Seinkmane, E., -
© 2005 Nature Publishing Group Endophilin and CtBP/BARS are ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/GallopEndopohilinNature2005.pdf4 Jan 2006: Nature 401, 133–-141 (1999). 2. Modregger, J., Schmidt, A. A., Ritter, B., Huttner, W. ... M., Watson, M. D. & Slabas, A. R.Isolation and characterisation of a maize cDNA that complements a 1-acylsn-glycerol-3-phosphate acyltransferase mutant of -
Coot Scripting Interface: c-interface.h Source File
https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/docs/html/c-interface_8h_source.html24 Aug 2021: 398 / return a list or python false /. 399 PyObject remarks_py(int imol);. ... 629 does not have the _raw suffix and returns a scheme or python. -
INVITED REVIEW Mechanosensory molecules and circuits in C. elegans ...
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-2.pdf10 Dec 2014: providing decisive evidence that TRP-4 is a pore-forming ionchannel subunit [39]. ... elegans. Neuron 70(2):299–309. doi:10.1016/j.neuron.2011.02.046. 17. Chatzigeorgiou M, Yoo S, Watson JD, Lee WH, Spencer WC, KindtKS, Hwang SW, Miller DM 3rd, -
Proteins containing photosynthetic reaction centre domains modulate…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Nussbaum_Nat_micro_2024.pdf1 Mar 2024: expressing CdpB2–mNeonGreen from a plasmid under the control of its native promotor. ... Few PRC proteins are associated with other domains such as a zinc ribbon. -
Jason William Chin Page 1 of 18 MRC Laboratory ...
https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-content/uploads/2024/01/Chin-cv-26012024.pdf29 Jan 2024: assembly. J. F. Zürcher, A. A. Kleefeldt, L. F. H. Funke, J. ... J. L. Watson, S. Aich, B. Oller-Salvia, A. A. Drakek, S. -
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29
https://www2.mrc-lmb.cam.ac.uk/groups/sbullock/wp-json/wp/v2/pages/29 -
doi:10.1016/j.neuron.2005.05.004
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Jockusch_Neuron2005.pdf17 Jun 2005: B) Examples of capacitancemresponses elicited by a depolarization lasting 100 ms (deliveredDat arrow). ... Neuron 17, 1241–1249. Miele, A.E., Watson, P.J., Evans, P.R., Traub, L.M., and Owen, D.J.(2004). -
Recordings - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/about-lmb/archive/recordings/21 Jul 2023: Isaac Asimov introduces James Watson and Francis Crick in the story of the structure of DNA, 8 July 1974. ... Discovering the double helix. James Watson talks about the discovery of the double helix in a lecture at Cold Spring Harbor Laboratory, November -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/31 May 2024: Arka Chakraborty is carrying on structural work on a related complex, ATR/ATRIP. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J., Putker, M., -
LMB 365 - Day 60 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-60/28 Feb 2019: Published on. 1 March, 2019. This image for day 60 of #LMB365 shows a handful of pseudocoloured hippocampal neurons (brain cells) that have been specifically targeted with DNA expressing a fluorescent ... protein which has allowed Jake Watson to -
LMB 365 - Day 100 - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/lmb-365-day-100/9 Apr 2019: By simulating the activity of individual synapses on a neuron, seen as deflections in this image for day 100 of #LMB365, Jake Watson in Ingo Greger’s group in Neurobiology can -
nature14896 493..505
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/95_Brown_A_Nature_2015.pdf19 Aug 2015: with its Watson–Crick edge. ... 4b, c). The main chain of Cys127 from the YxCxxxFmotif can form two hydrogen bonds with the Watson–Crick edge ofA1825 to stabilize its flipped orientation, facilitating stacking of the 12and -
Tyrosine Residues in Phospholipase C�2 Essential for the…
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/11606584.pdf20 Apr 2002: The excitation wavelength was 490 nm, and emission wasmonitored at a wavelength of 535 nm. ... Afterseparation by SDS-PAGE, the gel was subjected to analysis using a PhosphorImager. -
How cellular clocks within heart cells coordinate daily cardiac…
https://www2.mrc-lmb.cam.ac.uk/how-cellular-clocks-within-heart-cells-coordinate-daily-cardiac-rhythms/15 Oct 2021: cells make as great a contribution to daily variation in heart rate as signals from the nervous system. ... Stangherlin, A., Watson, J.L., Wong, D.C.S., Barbiero, S., Zeng, A., Seinkmane, E., Peak Chew, S., Beale, A.D., Hayter, E.A., Guna, A., Inglis, A.J -
PII: S1097-2765(03)00356-3
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/gripdomain.pdf27 Oct 2003: isoleucine makes a shallower contact withof Arf1, corresponding to Tyr 77 in Arl1. ... genes. Proc. Natl. Acad. Sci. USA90, 8952–8956.Analytical UltracentrifugationCollins, B.M., Watson, P.J., and Owen, D.J. -
Twinning and other pathologies Andrey Lebedev CCP4 OD-‐structures…
https://www2.mrc-lmb.cam.ac.uk/download/twinningaandaotherapathologiesa-andreyalebedeva-a/?wpdmdl=18788&refresh=6697dff39d6ea172122929911 Jun 2013: 04/06/2013 Crystallography Course LMB 13. a'. a c. c'. Uppenberg et al. ... a. b. Human macrophage receptor CLEC5A for dengue virus Watson, A. -
9780470015902.a0029223
https://www2.mrc-lmb.cam.ac.uk/groups/greger/wp-content/uploads/sites/32/eLS-review_Greger.pdf1 Mar 2022: AMPA ReceptorsAlexandra Pinggera, MRC Laboratory of Molecular Biology, Cambridge, UKJake F Watson, MRC Laboratory of Molecular Biology, Cambridge, UKIngo H Greger, MRC Laboratory of Molecular Biology, Cambridge, UK. ... Science 287 (5461): 2262–2267.DOI -
Supplemental Materials Supp MethodsSupp Fig. 1 Sequence conservation…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/AP2Hub_EMBO2004/AP2Praefcke2004Sup.pdf23 Nov 2004: Q F Q N F L P T V V H P G D L Q T Q L A V Q T K R V A A Q V D ... J Biol Chem278, 46772-46781. Miele, A. E., Watson, P. J., Evans, P. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/28a/linlia href="#walker"John Walker/a/linlia href="#watson"James Watson/a/lin/uln/div/pnh2 id="arndt"Uli Arndt/h2npimg loading="lazy" decoding="async" width="130" height="200" ... Video Tape: 107 minutes, Wellcome Medical Science Video Archive./linliSee -
New method to untangle the contribution of signalling pathways…
https://www2.mrc-lmb.cam.ac.uk/new-method-to-untangle-the-contribution-of-signalling-pathways-involved-in-asymmetric-cell-division/28 Sep 2023: In this study, co-led by Joseph Watson and Lara Krüger, the team developed an assay which allows the contribution of each pathway involved in the process to be dissected. ... Watson, JL., Krüger, LK., Ben-Sasson, AJ., Bittleston, A., Shahbazi, M., -
Functional Depletion of Mahogunin by Cytosolically Exposed Prion…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/59_Chakrabarti_O_Cell_2009.pdf13 Jun 2009: Some familial PrP mutants generateincreased CtmPrP, a transmembrane isoform associ-ated with disease. ... a direct correlation between the extent of cytosolic PrP exposure. and Mgrn dysfunction. -
Publications
https://www2.mrc-lmb.cam.ac.uk/groups/greger/publications/Commun Biol 4(1): 1056. Watson, J.F., Pinggera, A., Ho, H., Greger, I.H. ... Structure 27(2): 241-252.e3. Buonarati, O.R., Hammes, E.A., Watson, J.F., Greger, I.H., Hell, J.W.
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