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Protein-driven membrane stresses in fusion and fission
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/KozlovCurvature2010.pdf21 Feb 2011: However, the fusion peptideis clearly more than just a hold on a target membrane,because some amino acid substitutions within the fusionpeptide inhibit fusion without lowering peptide–mem-brane binding. ... membrane stresses, has been confirmed in some -
Protein targeting and degradation are coupled for elimination of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/73_Hessa_T_Nature_2011.pdf14 Jul 2011: 3b, c). Thus, the Bag6 complex captures substratesconcomitant with or after the release of nascent chains from the ribo-some; these same hydrophobic domains are bound by the SRP as longas ... After ubiquitination,BAG6 might chaperone its -
JCB: Article The Rockefeller University Press $30.00J. Cell Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/J%20Cell%20Biol%202010%20Howes.pdf24 Aug 2011: We next sought to verify some key targets as novel cargo for the CLIC pathway. ... In some instances, intriguing tubular networks were seen with labeling for anti–CD44-HRP after 40 min of internal-ization (Fig. -
Membrane Protein Insertion at the Endoplasmic Reticulum
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/75_Shao_S_Ann_Rev_2011.pdf9 Nov 2011: Most types of membrane proteins are inserted by a cotranslational pathway, although some use a posttranslational pathway.ER, endoplasmic reticulum. ... c) Three-dimensional structure of bovine rhodopsin showing that TMDs arehighly variable in structure;
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