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Alan Fersht | 03 - 05 Sept 2017 Cambridge, UK
https://www.ch.cam.ac.uk/pfei/alan-fersht9 Jul 2024: Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... It is a major hub protein and interacts with a host of other proteins involved in the cell cycle. -
Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry
https://www.ch.cam.ac.uk/person/arf259 Jul 2024: Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: The Y220X Paradigm. ... Eur J Med Chem. (2018). 152,. 101. (doi:The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 protein to -
CDD-MRC Conference on “Genes vs Environment in Cancer” | MRC…
https://www.mrc-tox.cam.ac.uk/news/cdd-mrc-conference-genes-vs-environment-cancer10 Jul 2024: During the conference the Prof. Karen Vousden from The Crick Institute, London, was awarded of the CDD Award 2018 for her pioneering studies on the function of the tumour suppressor protein ... p53 in the response to environmental stressors. -
Extra centrosomes and cancer : New light on a century old problem |…
https://www.gen.cam.ac.uk/news/coelho-extra-centrosomes-and-cancer10 Jul 2024: The net result is hyperplasia in several tissues, which is exacerbated by the additional loss of the tumour suppressor protein p53. ... p53 is non-functional in the majority of human tumours and mice lacking p53 are prone to tumour development. -
Therapeutic vulnerabilities in lung tumours with distinct p53…
https://www.medschl.cam.ac.uk/therapeutic-vulnerabilities-lung-tumours-distinct-p53-deficiencies/23 Feb 2024: School of Clinical Medicine. Featured Articles. Therapeutic vulnerabilities in lung tumours with distinct p53 deficiencies. ... models harboring distinct p53 deficiencies, namely complete loss of p53 (Null); mutations that cause loss of p53 contact with -
Publications - Kaser Group
https://www.med.cam.ac.uk/kaser/publications/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Kaser Group. Publications. Reviews & Editorials. 2024 University of Cambridge. -
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https://publications.ch.cam.ac.uk/publications-search?page=7869 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on -
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https://publications.ch.cam.ac.uk/publications-search?page=8909 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on -
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https://publications.ch.cam.ac.uk/publications-search?page=11299 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on -
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https://publications.ch.cam.ac.uk/publications-search?page=8019 Jul 2024: DOI:J Blumberger – Physical Chemistry Chemical Physics (2008) 10, 5651. (DOI:MR Fernandez-Fernandez, TJ Rutherford, AR Fersht – Protein Sci (2008) 17, 1663.
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