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1 - 10 of 143 search results for `protein p53`

  1. Fully-matching results

  2. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3293

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3293

  3. Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry

    https://www.ch.cam.ac.uk/person/arf25
    26 Jul 2024: Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ... European journal of medicinal chemistry. (2018). 152,. 101. (doi:The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53

  4. Alan Fersht | 03 - 05 Sept 2017 Cambridge, UK

    https://www.ch.cam.ac.uk/pfei/alan-fersht
    26 Jul 2024: Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... It is a major hub protein and interacts with a host of other proteins involved in the cell cycle.

  5. Unknome v3

    https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/0/
    InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.
    By: Tim Stevens

  6. Unknome v3

    https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP10295/
    EMBL (2). InterPro (1). 0.0. TP53I13. Tumor protein p53 inducible protein 13. ... None. GO (7). 0.5. Tp53i13. Tumor protein p53-inducible protein 13. None.
    By: Tim Stevens

  7. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117
    Alan rejoined the LMB in 2010, where he continued his work on protein folding, misfolding and disease, concentrating on the tumour suppressor p53 until the end of 2017. ... n. Cancer is a disease of mutation, and the most commonly mutated protein by far

  8. Unknome v3

    https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/1/
    InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.
    By: Tim Stevens

  9. Unknome v3

    https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/3/
    InterPro (1). 0.0. 100306543. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. 100824728. p53 and DNA damage-regulated protein 1. None.
    By: Tim Stevens

  10. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/11070

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/11070
    can bind to and deactivate an enzyme that controls the stability of the p53 tumour suppressor protein. ... This deactivation allows p53 to be turned on, putting the brakes on cancer growth.

  11. Therapeutic vulnerabilities in lung tumours with distinct p53…

    https://www.medschl.cam.ac.uk/therapeutic-vulnerabilities-lung-tumours-distinct-p53-deficiencies/
    23 Feb 2024: School of Clinical Medicine. Featured Articles. Therapeutic vulnerabilities in lung tumours with distinct p53 deficiencies. ... models harboring distinct p53 deficiencies, namely complete loss of p53 (Null); mutations that cause loss of p53 contact with

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