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search results for `protein p53` |u:www.ch.cam.ac.uk
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Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry
https://www.ch.cam.ac.uk/person/arf2526 Jul 2024: Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: the Y220X Paradigm. ... European journal of medicinal chemistry. (2018). 152,. 101. (doi:The curcumin analog HO-3867 selectively kills cancer cells by converting mutant p53 -
Alan Fersht | 03 - 05 Sept 2017 Cambridge, UK
https://www.ch.cam.ac.uk/pfei/alan-fersht26 Jul 2024: Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... It is a major hub protein and interacts with a host of other proteins involved in the cell cycle. -
Part II Exam Questions Reports 2018/19 (incomplete) Paper 1 ...
https://www.ch.cam.ac.uk/teaching/files/Examiners%20Reports/Part%20II_ExamReports%20_2018-19.pdf9 Jul 2024: The best students got this correct. Many students also thought the protein, p53 had disulphide bridges. ... p53 was covered in the lectures as a nuclear protein that bound DNA so they should have been aware it is in a reducing environment.
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