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22 Jul 2024: René Bernards . Thesis: Escaping growth arrest in cancer – Bypass of a p53 dependent cell cycle arrest. ... Suppression of the p53-dependent replicative senescence response by lysophosphatidic acid signaling.

22 Jul 2024: Khoronenkova SV, Dianov GL (2013). USP7S-dependent inactivation of Mule regulates DNA damage signalling and repair. ... ATM-dependent downregulation of USP7/HAUSP by PPM1G activates p53 response to DNA damage.

22 Jul 2024: Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. ... Genomic instability in mutant p53 cancer cells upon entotic engulfment.

22 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

22 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

22 Jul 2024: and Hengartner, MO., 2004. Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. ... Ce-TACC, a C.elegans centrosomal protein required for MT dependent processes CELL MOTILITY AND THE CYTOSKELETON, v.

23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Lab Investigation doi: 10.1038/labinvest.2011.96 . McDuff F.K.E

23 Feb 2024: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. ... CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.

18 Jul 2024: 1474. (doi: 10.1016/j.bpj.2020.09.007). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

23 Feb 2024: School of Clinical Medicine. Featured Articles. Therapeutic vulnerabilities in lung tumours with distinct p53 deficiencies. ... To identify mutant p53-dependent therapeutic vulnerabilities in lung tumours, Dr Carla Martins and her colleagues at the MRC

23 Feb 2024: A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

22 Jul 2024: and Festing, MF., 1999. Low levels of p53 are associated with resistance to tetrachlorodibenzo-p-dioxin toxicity in DBA/2 mice. ... DNA-damaging agents induce both p53-dependent and p53-independent apoptosis in immature thymocytes.

18 Jul 2024: Weather. (2020). 75,. 353. (doi: 10.1002/wea.3795). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q. –.

18 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

23 Feb 2024: Cambridge Cardiovascular - Functional Genomics https://www.cardiovascular.cam.ac.uk/directory/research-themes/functional-genomics Functional Genomics theme led by Prof Nicole Soranzo performs epigenomic annotation of cells relevant to the

23 Feb 2024: His recent work is aimed at cell cycle dependent changes inmacrophage biological activity and viral permissivity.

23 Feb 2024: PK is a DNA sensor for IRF-3-dependent innate immunity</a></strong></span><br /> <span>BJ Ferguson, DS Mansur, NE Peters, H Ren, GL Smith (2012)</span><span>eLife Sciences ... and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in