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search results for `p53 Activity` |u:www2.mrc-lmb.cam.ac.uk
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Alan Fersht - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/alan-fersht/
21 Jul 2023:
We focus on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53, in order to design novel anti-cancer drugs that function by restoring the activity of ... Exploiting Transient Protein States for the Design of
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https://www2.mrc-lmb.cam.ac.uk/groups/fersht/26 Jan 2021: We focus on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53, in order to design novel anti-cancer drugs that function by restoring the activity of ... Tumour Suppressor p53. Structural Biology and Drug Discovery. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117We focus on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53, in order to design novel anti-cancer drugs that function by restoring the activity of ... n. Cancer is a disease of mutation, and the most commonly -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Krstic-Demonacos, N. B. La Thangue, A TPR motif cofactor contributes to p300 activity in the p53 response. ... Knapp, N. B. La Thangue, A. N. Bullock, The p53 cofactor Strap exhibits an unexpected TPR motif and oligonucleotide-binding (OB)-fold structure.
21 Jul 2023:
We focus on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53, in order to design novel anti-cancer drugs that function by restoring the activity of ... Exploiting Transient Protein States for the Design of
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