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1 - 2 of 2 search results for `p53 Activity` |u:www.ch.cam.ac.uk

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  2. Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry

    https://www.ch.cam.ac.uk/person/arf25
    26 Jul 2024: doi:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C. ... Cancers (Basel). (2019). 11,. 1151. (doi:Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C

  3. Alan Fersht | 03 - 05 Sept 2017 Cambridge, UK

    https://www.ch.cam.ac.uk/pfei/alan-fersht
    26 Jul 2024: We focus on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53, in order to design novel anti-cancer drugs that function by restoring the activity of ... Cancer is a disease of mutation, and the most commonly mutated

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