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The actin ‘roads’ are built by three specialized proteins, Formin-2, Spire1 and Spire2, that assemble actin filaments from the vesicle surface. ... n. This work was supported by a Framework Programme-7 EU Grant, and the Medical Research Council.

To prevent errors in mitosis cells employ checkpoints that monitor and coordinate the correct order of events. ... Conformational variability of the complex allows for UbcH10 association, and they show from a structure of APC/C.

{"id":13411,"date":"2018-12-13T09:40:23","date_gmt":"2018-12-13T09:40:23","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=13411"},"modified":"2018-12-13T09:40:23","modified_gmt":"2018-12-13T09:40:23","slug":"catching-enzymes-in-the-act-of-makin

{"id":17528,"date":"2020-03-04T16:14:53","date_gmt":"2020-03-04T16:14:53","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=17528"},"modified":"2020-03-12T09:20:13","modified_gmt":"2020-03-12T09:20:13","slug":"how-alcohol-derived-dna-damage-is-fi

Each person lived in the laboratory for 49 days (without a clock, or any knowledge of external night and day). ... Melatonin is the main sleep hormone and is released from the pineal gland at night to make you feel sleepy.

{"id":19278,"date":"2020-10-21T16:32:12","date_gmt":"2020-10-21T15:32:12","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=19278"},"modified":"2020-11-03T14:39:08","modified_gmt":"2020-11-03T14:39:08","slug":"atomic-advance-for-cryo-em","status"

{"id":14750,"date":"2019-05-16T10:04:47","date_gmt":"2019-05-16T09:04:47","guid":{"rendered":"https://www2.mrc-lmb.cam.ac.uk/?p=14750"},"modified":"2019-07-05T10:06:25","modified_gmt":"2019-07-05T09:06:25","slug":"creating-an-entire-bacterial-genome-

Conformationally strained trans-cyclooctene with improved stability and excellent reactivity in tetrazine ligation. ... Lang, S. Wallace, R. A. Mehl, J. W. Chin. [Featured in News & Views Nature Chem.