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  2. 6. Image refinement Sjors Scheres EM course 2017 Agenda ...

    https://www2.mrc-lmb.cam.ac.uk/download/cryo-em17-lecture-06-refinement/?wpdmdl=18760&refresh=668ff5b2bbbd31720710578
    4 Oct 2017: The bad news • The experimental data alone is not enough to determine a unique solu7on! • ... Danger of incorrect interpreta7on…. The good news. • By incorpora7ng external informa7on, a different problem may be solved for which a unique solu7on

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