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Guided Assembly and Patterning of Intrinsically Fluorescent Amyloid…
https://laser.ceb.cam.ac.uk/research/publication-summaries/guided-assembly-and-patterning-intrinsically-fluorescent-amyloid22 Jul 2024: Our findings suggest that microlevel confinement is key for the guided assembly of amyloids from monomeric proteins. -
Diode laser induced fluorescence spectroscopy for combustion…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/diode-laser-induced-fluorescence-spectroscopy-for-combustion-thermometry22 Jul 2024: Search site. Laser Analytics Group. Diode laser induced fluorescence spectroscopy for combustion thermometry. Burns IS, Hult J, Kaminski CF (2005) "Diode laser induced fluorescence spectroscopy for combustion thermometry" Journal of Physics: -
High bandwidth absorption spectroscopy with a dispersed…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/high-bandwidth-absorption-spectroscopy-with-a-dispersed-supercontinuum-source22 Jul 2024: Search site. Laser Analytics Group. High bandwidth absorption spectroscopy with a dispersed supercontinuum source. Hult, J; Watt, RS; Kaminski, CF, "High bandwidth absorption spectroscopy with a dispersed supercontinuum source", OPTICS EXPRESS -
a-Synuclein – Regulator of Exocytosis, Endocytosis, or Both? | Laser…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/a-synuclein-2013-regulator-of-exocytosis-endocytosis-or-both22 Jul 2024: Search site. Laser Analytics Group. a-Synuclein – Regulator of Exocytosis, Endocytosis, or Both? Lautenschläger J, Kaminski CF, Kaminski Schierle GS, "α-Synuclein – Regulator of Exocytosis, Endocytosis, or Both?", Trends in Cell Biology (2017), -
Imaging Pharmaceutical Tablets with Optical Coherence Tomography |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/imaging-pharmaceutical-tablets-with-optical-coherence-tomography22 Jul 2024: Search site. Laser Analytics Group. Imaging Pharmaceutical Tablets with Optical Coherence Tomography. Mauritz J, Morrisby R, Hutton R, Legge C, Kaminski CF, "Imaging Pharmaceutical Tablets with Optical Coherence Tomography", Journal of -
Superresolving the kidney—a practical comparison of fluorescence…
https://laser.ceb.cam.ac.uk/research/publication-summaries/superresolving-kidney-practical-comparison-fluorescence-nanoscopy22 Jul 2024: Search site. Laser Analytics Group. Superresolving the kidney—a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier. Wunderlich L, Ströhl, F, Ströhl S, Vanderpoorten O, Mascheroni L, Kaminski CF. "Superresolving -
Correcting chromatic offset in multicolor super-resolution…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/correcting-chromatic-offset-in-multicolor-super-resolution-localization-microscopy22 Jul 2024: Search site. Laser Analytics Group. Correcting chromatic offset in multicolor super-resolution localization microscopy. Correcting chromatic offset in multicolor super-resolution localization microscopy, Erdelyi M, Rees EJ, Metcalf D, -
Supercontinuum radiation for applications in chemical sensing and…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/supercontinuum-radiation-for-applications-in-chemical-sensing-and-microscopy22 Jul 2024: A brief overview is given on the mechanisms of supercontinuum generation in solid core photonic crystal fibres, and then we review recent, and present new, results from our own research. -
Super-resolution fluorescent methods: where next for super-resolution …
https://laser.ceb.cam.ac.uk/publications/publication-summaries/super-resolution-fluorescent-methods-where-next-for-super-resolution22 Jul 2024: Search site. Laser Analytics Group. Super-resolution fluorescent methods: where next for super-resolution. Knight A, Kaminski CF and Sauer M, Super-resolution fluorescent methods: where next for super-resolution? Methods Appl. Fluoresc. 3 (2015) -
Silica-based photonic crystal fiber for the generation of broad band…
https://laser.ceb.cam.ac.uk/research/publication-summaries/silica-based-photonic-crystal-fiber-generation-broad-band-uv22 Jul 2024: Search site. Laser Analytics Group. Silica-based photonic crystal fiber for the generation of broad band UV radiation. Perret S, Poudel C, Ghosh AN, Fanjoux G, Provino L, Taunay T, Monteville A, Landais D, Kaminski CF, Dudley JM, Sylvestre T. "Silica -
Stimulated emission depletion microscopy to study amyloid fibril…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/stimulated-emission-depletion-microscopy-to-study-amyloid-fibril-formation22 Jul 2024: Search site. Laser Analytics Group. Stimulated emission depletion microscopy to study amyloid fibril formation. Mahou P, Curry N, Pinotsi D, Kaminski-Schierle G S, Kaminski C F, "Stimulated emission depletion microscopy to study amyloid fibril -
Protein released from cells triggers chain reactions which may cause…
https://laser.ceb.cam.ac.uk/news/protein-released-from-cells-triggers-chain-reactions-which-may-cause-alzheimers-disease22 Jul 2024: Tau is normally an intracellular protein and does no harm, however, if for some reason it is translocated to the outside of cells, our studies suggest that this could initiate the ... The findings were enabled by our development of a fluorescence -
EPSRC Centre for Doctoral Training announced in Sensor Technologies…
https://laser.ceb.cam.ac.uk/news/epsrc-centre-for-doctoral-training-announced-in-sensor-technologies-and-applications22 Jul 2024: Search site. Laser Analytics Group. EPSRC Centre for Doctoral Training announced in Sensor Technologies and Applications. The department of Chemical Engineering will host the EPSRC CDT in Sensor Technologies and Applications which will involve 50 -
Multiplexed absorption tomography with calibration-free wavelength…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/multiplexed-absorption-tomography-with-calibration-free-wavelength-modulation-spectroscopy22 Jul 2024: Search site. Laser Analytics Group. Multiplexed absorption tomography with calibration-free wavelength modulation spectroscopy. Multiplexed absorption tomography with calibration-free wavelength modulation spectroscopy, Cai W, Kaminski CF, Applied -
Spectrally resolved confocal fluorescence microscopy with a…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/spectrally-resolved-confocal-fluorescence-microscopy-with-a-supercontinuum-laser22 Jul 2024: Search site. Laser Analytics Group. Spectrally resolved confocal fluorescence microscopy with a supercontinuum laser. Schlachter S, Elder A, Frank JH, Grudinin A, Kaminski CF, "Spectrally resolved confocal fluorescence microscopy with a -
Combining sample expansion and light sheet microscopy for the…
https://laser.ceb.cam.ac.uk/research/publication-summaries/combining-sample-expansion-and-light-sheet-microscopy-volumetric22 Jul 2024: Search site. Laser Analytics Group. Combining sample expansion and light sheet microscopy for the volumetric imaging of virus-infected cells with super-resolution. Mascheroni L, Scherer KM, Manton JD, Ward EN, Dibben O, Kaminski CF. "Combining -
An open-source software package for on-the-fly deskewing and live…
https://laser.ceb.cam.ac.uk/research/publication-summaries/open-source-software-package-fly-deskewing-and-live-viewing22 Jul 2024: Search site. Laser Analytics Group. An open-source software package for on-the-fly deskewing and live viewing of volumetric lightsheet microscopy data. Lamb JR, Ward EN, Kaminski CF. "An open-source software package for on-the-fly deskewing and live -
A white light confocal microscope for spectrally resolved…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/a-white-light-confocal-microscope-for-spectrally-resolved-multidimensional-imaging22 Jul 2024: Search site. Laser Analytics Group. A white light confocal microscope for spectrally resolved multidimensional imaging. Frank, JH; Elder, AD; Swartling, J; Venkitaraman, AR; Jeyasekharan, AD; Kaminski, CF, "A white light confocal microscope for -
α-Synuclein fibril and synaptic vesicle interactions lead to vesicle…
https://laser.ceb.cam.ac.uk/research/publication-summaries/synuclein-fibril-and-synaptic-vesicle-interactions-lead-vesicle22 Jul 2024: Search site. Laser Analytics Group. α-Synuclein fibril and synaptic vesicle interactions lead to vesicle destruction and increased lipidassociated fibril uptake into iPSC-derived neurons. Stephens AD, Fernandez Villegas A , Chung CW, -
Structural analysis of herpes simplex virus by optical…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/structural-analysis-of-herpes-simplex-virus-by-optical-super-resolution-imaging22 Jul 2024: Search site. Laser Analytics Group. Structural analysis of herpes simplex virus by optical super-resolution imaging. Structural analysis of herpes simplex virus by optical super-resolution imaging. Laine R F. Albecka A, van de Linde S, Rees E J, -
ML-SIM: A deep neural network for reconstruction of structured…
https://laser.ceb.cam.ac.uk/research/publication-summaries/ml-sim-deep-neural-network-reconstruction-structured-illumination22 Jul 2024: The reconstruction quality enabled by our method is compared with traditional SIM reconstruction methods, and we demonstrate advantages in terms of noise, reconstruction fidelity and contrast for both simulated and experimental -
Localization microscopy for the study of amyloid fibril formation |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/localization-microscopy-for-the-study-of-amyloid-fibril-formation22 Jul 2024: Search site. Laser Analytics Group. Localization microscopy for the study of amyloid fibril formation. Localization microscopy for the study of amyloid fibril formation, Pinotsi D, Kaminski-Schierle GS, Rees EJ, Kaminski CF, Proc.SPIE 88150G, -
A label-free, quantitative assay of amyloid fibril growth based on…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/a-label-free-quantitative-assay-of-amyloid-fibril-growth-based-on-intrinsic-fluorescence22 Jul 2024: Search site. Laser Analytics Group. A label-free, quantitative assay of amyloid fibril growth based on intrinsic fluorescence. Pinotsi D, Buell AK, Dobson CM, Kaminski Schierle GS and Kaminski CF, "A label-free, quantitative assay of amyloid fibril -
Homographically generated light sheets for the microscopy of large…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/homographically-generated-light-sheets-for-the-microscopy-of-large-specimens22 Jul 2024: Search site. Laser Analytics Group. Homographically generated light sheets for the microscopy of large specimens. C. T. Russell, E. J. Rees, and C. F. Kaminski, "Homographically generated light sheets for the microscopy of large specimens," Opt. Lett -
Single particle trajectories reveal active endoplasmic reticulum…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/single-particle-trajectories-reveal-active-endoplasmic-reticulum-luminal-flow22 Jul 2024: Search site. Laser Analytics Group. Single particle trajectories reveal active endoplasmic reticulum luminal flow. Holcman D, Parutto P, Chambers JE, et al. "Single particle trajectories reveal active endoplasmic reticulum luminal flow." Nat. Cell -
The structure and global distribution of the endoplasmic reticulum…
https://laser.ceb.cam.ac.uk/research/publication-summaries/structure-and-global-distribution-endoplasmic-reticulum-network-are22 Jul 2024: Our results demonstrate a critical role of lysosome-regulated ER dynamics and reshaping in nutrient responses and neuronal development. -
Temperature response of turbulent premixed flames to inlet velocity…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/temperature-response-of-turbulent-premixed-flames-to-inlet-velocity-oscillations22 Jul 2024: Search site. Laser Analytics Group. Temperature response of turbulent premixed flames to inlet velocity oscillations. Flame–turbulence interactions are at the heart of modern combustion research as they have a major influence on efficiency, -
Fast and simple spectral FLIM for biochemical and medical imaging |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/fast-and-simple-spectral-flim-for-biochemical-and-medical-imaging22 Jul 2024: Search site. Laser Analytics Group. Fast and simple spectral FLIM for biochemical and medical imaging. M Popleteeva, K T Haas, D Stoppa, L Pancheri, L Gasparini, C F Kaminski, L D Cassidy, A R Venkitaraman and A Esposito, "Fast and simple spectral -
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins …
https://laser.ceb.cam.ac.uk/research/publication-summaries/site-ribosome-remodeling-locally-synthesized-ribosomal-proteins-axons22 Jul 2024: Search site. Laser Analytics Group. On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons. Shigeoka T, Koppers M, Wong HHW, Lin JQ, Cagnetta R, Dwivedy A, Nascimento JF, Van Tartwijk FW, Ströhl F, Cioni J-M, Schaeffer J, -
MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3 | Laser…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/mbnl1-and-ptb-cooperate-to-repress-splicing-of-tpm1-exon-322 Jul 2024: Our data suggest that the smooth muscle splicing of Tpm1 is mediated by allosteric assembly of an RNA–protein complex minimally comprising PTB, MBNL and their cognate RNA-binding sites. -
Opal-like Multicolor Appearance of Self-Assembled Photonic Array |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/opal-like-multicolor-appearance-of-self-assembled-photonic-array22 Jul 2024: Search site. Laser Analytics Group. Opal-like Multicolor Appearance of Self-Assembled Photonic Array. Arnon ZA, Pinotsi D, Schmidt M, et al. "Opal-like Multicolor Appearance of Self-Assembled Photonic Array." ACS Appl. Mater. Interfaces. (2018), -
Revealing nanomechanical domains and their transient behavior in…
https://laser.ceb.cam.ac.uk/research/publication-summaries/revealing-nanomechanical-domains-and-their-transient-behavior-mixed22 Jul 2024: Search site. Laser Analytics Group. Revealing nanomechanical domains and their transient behavior in mixed-halide perovskite films. Mela I, Poudel C, Anaya M, Delport G, Frohna K, Macpherson S, Doherty TAS, Scheeder A,Stranks SD, Kaminski CF. -
Converting lateral scanning into axial focusing to speed up…
https://laser.ceb.cam.ac.uk/research/publication-summaries/converting-lateral-scanning-axial-focusing-speed-three-dimensional22 Jul 2024: Search site. Laser Analytics Group. Converting lateral scanning into axial focusing to speed up three-dimensional microscopy. Chakraborty T, Chen B, Daetwyler S, Chang BJ, Vanderpoorten O, Sapoznik E, Kaminski CF, Knowles TPJ, Dean KM, Fiolka R. -
Structured illumination microscopy with extended axial resolution…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/structured-illumination-microscopy-with-extended-axial-resolution-through-mirrored-illumination22 Jul 2024: Search site. Laser Analytics Group. Structured illumination microscopy with extended axial resolution through mirrored illumination. Manton JD, Ströhl F, Fiolka R, Kaminski CF, Rees EJ. "Structured illumination microscopy with extended axial -
Two-line atomic fluorescence flame thermometry using diode lasers |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/two-line-atomic-fluorescence-flame-thermometry-using-diode-lasers22 Jul 2024: Search site. Laser Analytics Group. Two-line atomic fluorescence flame thermometry using diode lasers. Hult, J; Burns, IS; Kaminski, CF, "Two-line atomic fluorescence flame thermometry using diode lasers", PROCEEDINGS OF THE COMBUSTION INSTITUTE -
Supercontinuum radiation in fluorescence microscopy and biomedical…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/supercontinuum-radiation-in-fluorescence-microscopy-and-biomedical-imaging-applications22 Jul 2024: Search site. Laser Analytics Group. Supercontinuum radiation in fluorescence microscopy and biomedical imaging applications. Poudel C, Kaminski CF. "Supercontinuum radiation in fluorescence microscopy and biomedical imaging applications." Journal of -
Visualizing electromagnetic fields at the nanoscale by single…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/visualizing-electromagnetic-fields-at-the-nanoscale-by-single-molecule-localization22 Jul 2024: Search site. Laser Analytics Group. Visualizing electromagnetic fields at the nanoscale by single molecule localization. Steuwe C, Erdelyi M, Szekeres G, Csete M, Baumberg J, Mahajan S, Kaminski CF, Visualizing electromagnetic fields at the -
The Homeostasis of Plasmodium falciparum-Infected Red Blood Cells |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/the-homeostasis-of-plasmodium-falciparum-infected-red-blood-cells22 Jul 2024: Search site. Laser Analytics Group. The Homeostasis of Plasmodium falciparum-Infected Red Blood Cells. Mauritz J, Esposito A, Ginsburg H, Kaminski CF, Tiffert T and Lew VL, "The Homeostasis ofPlasmodium falciparum Infected Red Blood Cells", PLoS -
Design and application of a confocal microscope for spectrally…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/design-and-application-of-a-confocal-microscope-for-spectrally-resolved-anisotropy-imaging22 Jul 2024: Search site. Laser Analytics Group. Design and application of a confocal microscope for spectrally resolved anisotropy imaging. Esposito A, Bader AN, Schlachter SC, van den Heuvel DJ, Kaminski Schierle GS, Venkitaraman AR, Kaminski CF, Gerritsen HC, -
Structural basis of synaptic vesicle assembly promoted by a-synuclein …
https://laser.ceb.cam.ac.uk/publications/publication-summaries/structural-basis-of-synaptic-vesicle-assembly-promoted-by-a-synuclein22 Jul 2024: Our results characterize the nature of the active conformations of αS that mediate the clustering of synaptic vesicles, and indicate their relevance in both functional and pathological contexts. -
On-Chip Super-Resolution Imaging with Fluorescent Polymer Films |…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/on-chip-super-resolution-imaging-with-fluorescent-polymer-films22 Jul 2024: Search site. Laser Analytics Group. On-Chip Super-Resolution Imaging with Fluorescent Polymer Films. Pang C, Li J, Tang M, Wang J, Mela I, Ströhl F, Hecker L, Shen W, Liu Q, Liu X, Wang Y, Zhang H, Xu M, Zhang X, Liu X, Yang Q & Kaminski CF. -
A FRET sensor for non-invasive imaging of amyloid formation in vivo | …
https://laser.ceb.cam.ac.uk/publications/publication-summaries/a-fret-sensor-for-non-invasive-imaging-of-amyloid-formation-in-vivo22 Jul 2024: We describe here, however, a Förster resonance energy transfer sensor that permits the aggregation kinetics of amyloidogenic proteins to be quantified in living systems by exploiting our observation that amyloid assemblies ... Our study confirms the -
Detection of Plasmodium falciparum-infected red blood cells by…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/detection-of-plasmodium-falciparum-infected-red-blood-cells-by-optical-stretching22 Jul 2024: Search site. Laser Analytics Group. Detection of Plasmodium falciparum-infected red blood cells by optical stretching. Mauritz J, Tiffert T, Seear R, Lautenschläger F, Esposito A, Lew V, Guck J, Kaminski F, "Detection ofPlasmodium falciparum -
Nanofluidic Traps by Two-Photon Fabrication for Extended Detection of …
https://laser.ceb.cam.ac.uk/research/publication-summaries/nanofluidic-traps-two-photon-fabrication-extended-detection-single22 Jul 2024: Using confocal fluorescence burst detection, we validated the functionality of particle confinement in our nanotrap geometries through measurement of particle residence times. ... Our approach thus opens up the possibility for single-molecule studies at -
MhFLIM: Resolution of heterogeneous fluorescence decays in widefield…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/mhflim-resolution-of-heterogeneous-fluorescence-decays-in-widefield-lifetime-microscopy22 Jul 2024: Search site. Laser Analytics Group. MhFLIM: Resolution of heterogeneous fluorescence decays in widefield lifetime microscopy. Schlachter S, Elder AD, Esposito A, Kaminski GS, Frank GH, van Geest LK, and Kaminski CF, "mhFLIM: Resolution of -
Label-free nanoscopy enabled by coherent imaging with photonic…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/label-free-nanoscopy-enabled-by-coherent-imaging-with-photonic-waveguides22 Jul 2024: Search site. Laser Analytics Group. Label-free nanoscopy enabled by coherent imaging with photonic waveguides. Ströhl F, Opstad IS, Tinguely J-C, Dullo FT, Ahluwalia BS, Kaminski CF. "Label-free nanoscopy enabled by coherent imaging with photonic -
CYK4 promotes antiparallel microtubule bundling by optimizing MKLP1…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/cyk4-promotes-antiparallel-microtubule-bundling-by-optimizing-mklp1-neck-conformation22 Jul 2024: Our data reveal that CYK4 binds to a globular mass in the atypically long MKLP1 neck domain between the catalytic core and the coiled coil and thereby reconfigures the two motor ... Our work provides insights into the microtubule bundling during -
Surface Enhanced Coherent Anti-Stokes Raman Scattering on…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/surface-enhanced-coherent-anti-stokes-raman-scattering-on-nanostructured-gold-surfaces22 Jul 2024: We demonstrate strong correlation between plasmon resonances and surface-enhanced CARS (SECARS) intensities on our nanostructured surfaces and show that an enhancement of 105 can be obtained over standard CARS. ... We also demonstrate SECARS imaging of -
Optical Detection of the Anesthetic Agent Propofol in the Gas Phase | …
https://laser.ceb.cam.ac.uk/publications/publication-summaries/optical-detection-of-the-anesthetic-agent-propofol-in-the-gas-phase22 Jul 2024: Search site. Laser Analytics Group. Optical Detection of the Anesthetic Agent Propofol in the Gas Phase. Laurila TK, Sorvajarvi T, Saarela J, Toivonen J, Wheeler DW, Ciaffoni L, Ritchie GAD, and Kaminski CF,"Optical Detection of the Anesthetic Agent -
ANALYSIS AND QUANTIFICATION OF MULTI-DIMENSIONAL CONFOCAL MICROSCOPY…
https://laser.ceb.cam.ac.uk/publications/publication-summaries/analysis-and-quantification-of-multi-dimensional-confocal-microscopy-data22 Jul 2024: Search site. Laser Analytics Group. ANALYSIS AND QUANTIFICATION OF MULTI-DIMENSIONAL CONFOCAL MICROSCOPY DATA. Multi-dimensional fluorescence microscopy seeks to measure many aspects of fluorescence emission, such as: excitation and emission spectra,
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