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22 Jul 2024: Our dSTORM microscope platform serves equally well for use in other single molecule and high resolution imaging modalities such as PALM, SOFI etc. ... We develop our own algorithms and software to reconstruct superresolution images from SIM and mSIM

22 Jul 2024: The algorithm, available to download free here, is a treats the problem like a widefield imaging technique and is more efficient and less prone to artefacts than conventional algorithms that treat

22 Jul 2024: Search site. Laser Analytics Group. Biophotonics of Native Silk Fibrils. U. Shimanovich, D. Pinotsi, K. Shimanovich, N. Yu, S. Bolisetty, J. Adamcik, R. Mezzenga, J. Charmet, F. Vollrath, E. Gazit, C. M. Dobson, G. Kaminski-Schierle, C. Holland, C.

22 Jul 2024: Search site. Laser Analytics Group. AC electrokinetic manipulation of DNA. Walti, C; Germishuizen, WA; Tosch, P; Kaminski, CF; Davies, AG, "AC electrokinetic manipulation of DNA", JOURNAL OF PHYSICS D-APPLIED PHYSICS 40:114-118(2007),

22 Jul 2024: Optical imaging of this self-assembly process in vitro and in cells is revolutionising our understanding of the molecular mechanisms behind these devastating diseases.

22 Jul 2024: Search site. Laser Analytics Group. Phi-squared fluorescence lifetime imaging. Elder AD, Kaminski CF,and Frank, JH, "Phi-Squared FLIM: a technique for alias-free frequency domain fluorescence lifetime imaging", Optics Express Vol. 17, Iss. 25, pp.

22 Jul 2024: Search site. Laser Analytics Group. Fluorescence Imaging of Reactive Processes. Kaminski, CF, "Fluorescence imaging of reactive processes", ZEITSCHRIFT FUR PHYSIKALISCHE CHEMIE-INTERNATIONAL JOURNAL OF RESEARCH IN PHYSICAL CHEMISTRY & CHEMICAL

22 Jul 2024: Search site. Laser Analytics Group. News prior to 2013. A selection of our group's news prior to 2013. ... All articles are free to download and more information is found under: Quantitative Fluorescence Microscopy Issue.

22 Jul 2024: Our group has pioneered the use of single molecule localisation microscopy, for the development of which Dr. ... For more information about super-resolution microscopy and how this is being applied to the study of the molecular mechanism of disease

22 Jul 2024: Search site. Laser Analytics Group. Aggregation rates of amyloid beta increase dramatically in acidic vesicles. New research by the Laser Analytics Group sheds light on the protein aggregation reactions at the heart of Alzheimer's disease. Research

22 Jul 2024: Search site. Laser Analytics Group. Super-condenser enables labelfree nanoscopy. Ströhl F, Opstad IS, Tinguely JC, Dullo FT, Mela I, Osterrieth JWM, Ahluwalia BS, Kaminski CF, "Super-condenser enables labelfree nanoscopy", Opt. Express (2019)

22 Jul 2024: So why should we not benefit from what nature discovered in designing our own new technologies? ... In an article with the intriguing title ‘Crystals: animal, vegetable or mineral?’, Hyde [3] explores the evolution of our understanding of

22 Jul 2024: Intriguingly our research, and that of others, show that the protein can form so called ‘hydrogels’, soft jelly like structures, that consist mostly of water, rather like the Jello Cubes shown ... in our group.

22 Jul 2024: Search site. Laser Analytics Group. MAI-SIM: interferometric multicolor structured illumination microscopy for everybody. Ward EN, Hecker L, Christensen CN, Lamb JR, Lu M, Mascheroni L, Chung CE, Wang A, Rowlands CJ, Kaminski Schierle GS, Kaminski CF

22 Jul 2024: Search site. Laser Analytics Group. A super-condenser for labelfree nanoscopy. Ströhl F, Opstad IS, Tinguely J-C, Dullo FT, Mela I, Osterrieth WM, Ahluwalia BS, Kaminski CF. A super-condenser for labelfree nanoscopy. ArXiv: 1905.02.401v1 (2019) DOI.

22 Jul 2024: Search site. Laser Analytics Group. Frontiers in structured illumination microscopy. Ströhl F, Kaminski CF, "Frontiers in structured illumination microscopy", Optica (2016), 3(6), 667-677. DOI:Abstract. At the start of this millennium, the

22 Jul 2024: One of the central research themes in our group is the development of modern laser imaging methods that shed light on the molecular mechanisms of devastaing diseases. ... Not only do we train our lasers in our fight against these diseases, but also our

22 Jul 2024: Search site. Laser Analytics Group. Theodor Fçrster: A Giant of Modern Photochemistry. Related links. Stub for c4e7b7c4b91d478cb7b2d44d598c6792. Contact us. Professor Clemens Kaminski. Department of Chemical Engineering & Biotechnology. University

22 Jul 2024: Search site. Laser Analytics Group. Flame growth and wrinkling in a turbulent flow. Kaminski, CF; Bai, XS; Hult, J; Dreizler, A; Lindenmaier, S; Fuchs, L, "Flame growth and wrinkling in a turbulent flow", APPLIED PHYSICS B-LASERS AND OPTICS

22 Jul 2024: Search site. Laser Analytics Group. New Paper and Video on SIM Processing. Watch Florian Ströhl, PhD student in the Laser Analytics group, talk about his latest research in which he outlines the advantages of a new deconvolution algorithm he

22 Jul 2024: Search site. Laser Analytics Group. Introduction to ‘Sensors in technology and nature’. Kaminski CF, da Cruz Vasconcellos F, Hadeler O, "Introduction to ‘Sensors in technology and nature’", Interface Focus (2016), 6: 20160034. Contact us.

22 Jul 2024: Search site. Laser Analytics Group. De novo design of a biologically active amyloid. Gallardo R, Ramakers M, De Smet F, Claes F, Khodaparast L, Khodaparast L, Couceiro JR, Langenberg T, Siemons M, Nyström S, Young LJ, Laine RF, Young L, Radaelli E,

22 Jul 2024: Search site. Laser Analytics Group. Prof. Clemens Kaminski elected Fellow of the Optical Society of America. Prof. Clemens Kaminski was elected as a Fellow of the Optical Society of America (OSA) in recognition of "pioneering work in the development

22 Jul 2024: Search site. Laser Analytics Group. Pint of Science festival: Probing the machinery of life at high resolution. The work of the Laser Analytics Group was recently presented at the Pint of Science festival. The Pint of Science festival provides a

22 Jul 2024: Search site. Laser Analytics Group. Group members elected as postdoctoral fellows of Robinson and Churchill Colleges. Congratulations to Claire Michel, Romain Laine, and Weiwei Cai for. being elected into competitive postdoctoral fellowships at

22 Jul 2024: Search site. Laser Analytics Group. Elements of image processing in localization microscopy. Rees EJ, Erdelyi M, Kaminski-Schierle GS, Knight AE and Kaminski CF, "Elements of image processing in localisation microscopy", Journal of Optics 15,

22 Jul 2024: Search site. Laser Analytics Group. Nathan Curry wins poster prize at Graduate Conference. Four group members presented work from their PhD at the annual Chemical Engineering and Biotechnology Department Graduate Conference. This included talks from

22 Jul 2024: pdf. Abstract. Our understanding of pH regulation within red blood cells (RBCs) has been inferred mainly from indirect experiments rather than from in situ measurements of intracellular pH (pHi).

22 Jul 2024: Search site. Laser Analytics Group. Laser Analytics group members win prize for best Masters research project. Kadi Liis Saar and Martin Chan win prize for best student research project for their work on the imaging of protein self assembly reactions

22 Jul 2024: Search site. Laser Analytics Group. Broadband trace sensing using supercontinuum light sources. The performance of the broadband technique, together with its conceptual simplicity and robust nature, make it well suited to a range of spectroscopic

22 Jul 2024: Our novel ‘OptoGenie’ stimulation device can be conveniently transferred between cell culture incubators for long-term stimulation, electrophysiology rigs for patch-clamp recordings, and optical microscopes for fluorescence imaging of cells.

22 Jul 2024: Search site. Laser Analytics Group. Intrinsically disordered proteins as molecular shields. Chakrabortee S, Tripathi R, Watson M, Kaminski Schierle GS, Kurniawan DP, Kaminski CF, Wise MJ, Tunnacliffe A, "Intrinsically disordered proteins as

22 Jul 2024: Search site. Laser Analytics Group. New Scientist: Tiny machines made of DNA origami may make antibiotics work better. Ioanna Mela's and the team's recent research on DNA origami has been featured in New Scientist. Origami isn’t usually thought

22 Jul 2024: Search site. Laser Analytics Group. Blind assessment of localisation microscope image resolution. Rees EJ, Erdelyi MJ, Pinotsi D, Knight A, Metcalf D and Kaminski CF, "Blind Assessment of Localisation Microscope Image Resolution", Optical Nanoscopy 1

22 Jul 2024: Search site. Laser Analytics Group. A new online tool for visualization of volumetric data. Fantham M, Kaminski CF, "A new online tool for visualization of volumetric data", Nature Photonics (2017), 11, 69. DOI:Abstract. New popular microscopy

22 Jul 2024: Search site. Laser Analytics Group. High-throughput, multi-parametric, and correlative fluorescence lifetime imaging. Poudel C, Mela I, Kaminski CF. "High-throughput, multi-parametric, and correlative fluorescence lifetime imaging" Methods and

22 Jul 2024: and that our material can therefore impose order onto fundamentally disordered substrates such as cell membranes. ... Our work provides a foundation for a synthetic cell biology in which multi-protein macroscale materials are designed to modulate cell

22 Jul 2024: Search site. Laser Analytics Group. Protein amyloids develop an intrinsic fluorescence signature during aggregation. Chan FTS, Kaminski Schierle GS, Kumita JR, Bertoncini CW, Dobson CM & Kaminski CF, "Protein amyloids develop an intrinsic

22 Jul 2024: Search site. Laser Analytics Group. Molecular Mechanisms of Cationic Fusogenic Liposome Interactions with Bacterial Envelopes. Scheeder A, Brockhoff M, Ward EN, Kaminski Schierle GS, Mela I, and Kaminski CF. "Molecular Mechanisms of Cationic

22 Jul 2024: Search site. Laser Analytics Group. Laser applications to chemical and environmental analysis: introduction. McNesby, K; Kaminski, C; Yalin, A, "Laser applications to chemical and environmental analysis: introducton", APPLIED OPTICS 44:3637-3637(2005

22 Jul 2024: Using our recently developed live-cell aggregation sensor in neuron-like cells, we demonstrate that different variants of exogenous monomeric Tau, namely full-length Tau (hTau40) and the Tau-derived construct ... Our data indicate a greater pathological

22 Jul 2024: Search site. Laser Analytics Group. Dispersion Measurement in Optical Fibers Using Supercontinuum Pulses. Hult, J; Watt, RS; Kaminski, CF, "Dispersion measurement in optical fibers using supercontinuum pulses", JOURNAL OF LIGHTWAVE TECHNOLOGY

22 Jul 2024: Search site. Laser Analytics Group. Diode Laser Induced Fluorescence for Gas-Phase Diagnostics. Burns IS, Kaminski CF, "Diode laser induced fluorescence for gas-phase diagnostics", Z. Phys. Chem., 225 (11-12), 1343-1368, (2011), | pdf. Abstract. We

22 Jul 2024: Our study introduces DNA origami as a tool in the fight against antibiotic resistance, and our results demonstrate the specificity and efficiency of the nanostructure as a drug delivery vehicle.

22 Jul 2024: Search site. Laser Analytics Group. Nano-vehicles give new lease of life to existing antimicrobials. Mela I, Kaminski CF. "Nano-vehicles give new lease fo lide to existing antimicrobials". Emerg Top Life Sci 4(6):555-566 (2020) DOI. Abstract.

22 Jul 2024: Search site. Laser Analytics Group. Nanoscale click-reactive scaffolds from peptide self-assembly. Guttenplan APM, Young LJ, Matak-Vinkovic D, Kaminski CF, Knowles TPJ Itzhaki LS, "Nanoscale click-reactive scaffolds from peptide self-assembly", J.

22 Jul 2024: Search site. Laser Analytics Group. Strong showing for Laser Analytics Group at the Microscience Microscopy Congress 2014. During a successful visit to the Microscience Microscopy Congress in Manchester nine group members presented their work. This

22 Jul 2024: Search site. Laser Analytics Group. Fast imaging of live organisms with sculpted light sheets. Fast imaging of live organisms with sculpted light sheets, Chmielewski AK, Kyrsting A, Mahou P, Wayland M, Muresan L, Evers JF, Kaminski CF, Scientific

22 Jul 2024: Search site. Laser Analytics Group. Fast, multicolour optical sectioning over extended fields of view with patterned illumination and machine learning. Ward EN, McClelland RM, Lamb JR, Rubio-Sánchez R, Christensen CN, Mazumder B, Kapsiani S,

22 Jul 2024: This phenomenon was measured experimentally following our observation in numerical simulations that exhibit so called ‘pulse wrap-around’ or ‘temporal aliasing’.