Search

18 May 2004: Anti-cancer drugs, which work by damaging DNA, exploit this mechanism in cancer cells with an intact p53 gene. ... However, cells without p300 could fully activate p53 and trigger their suicide mechanism in response to DNA damage.

27 Jul 2024: These results suggest that CRISPR/Cas9 selects against cells with a functional p53 pathway, which can explain the higher efficiency of CRISPR/Cas9 in tumour cell lines where the p53 DNA ... A delicate balance is required, however, as p53 inhibition can

11 Jun 2018: Absence of p53 in cells makes them more likely to become tumorous as damage can no longer be corrected. ... The team found that by decreasing activity of p53 in a cell, they could more efficiently edit healthy cells.

27 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

27 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

23 Feb 2024: Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner” Mol Cell. ... Watson JK, Rulands S, Wilkinson AC, Wuidart A, Ousset M, Van Keymeulen A, Göttgens B, Blanpain C, Simons BD, Rawlins EL, “Clonal Dynamics

27 Jul 2024: and Howarth, M., 2021. <i>Overcoming Symmetry Mismatch in Vaccine Nanoassembly through Spontaneous Amidation. ... H-J., Andersson, A-MC., Barrett, JR., Bowden, TA., Draper, SJ., Townsend, AR.

26 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and

19 Dec 2016: Formulation of delta screens can be generated on the Tab FORMULATION by entering the variables in the yellow cells. ... In Delta screen p53, component 7 is a cryoprotectant (glycerol). The concentration of cryoprotectant is increasing from left to right

14 Aug 2023: These techniques result in GMOs. Any artificial manipulation that invades living cells for the purpose of altering its genome13 in a direct way, including gene editing, constitutes genetic engineering. ... Recommendations for international and national