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1 - 10 of 1,166 search results for p53

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  2. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117

  3. p53 impairs CRISPR/Cas9 in healthy cells | Department of Biochemistry

    https://www.bioc.cam.ac.uk/news/archive/2018/p53-impairs-crispr-cas9-in-healthy-cells
    21 May 2024: RPE-1) cell line activate p53, causing cell growth arrest and DNA repair via the NHEJ pathway. ... A delicate balance is required, however, as p53 inhibition can leave cells vulnerable to tumorigenic mutations.

  4. Professor Sir Alan Fersht FRS | Yusuf Hamied Department of Chemistry

    https://www.ch.cam.ac.uk/person/arf25
    20 May 2024: Targeting Cavity-Creating p53 Cancer Mutations with Small-Molecule Stabilizers: The Y220X Paradigm. ... doi:A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C.

  5. Therapeutic vulnerabilities in lung tumours with distinct p53…

    https://www.medschl.cam.ac.uk/therapeutic-vulnerabilities-lung-tumours-distinct-p53-deficiencies/
    23 Feb 2024: School of Clinical Medicine. Featured Articles. Therapeutic vulnerabilities in lung tumours with distinct p53 deficiencies. ... Importantly, the authors identified a similar p53-mutation type specific gene expression signature in human lung tumors.

  6. Freeze Frame » West side of Sermilik Fjord

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-42
    You are in:Title: West side of Sermilik Fjord. Reference: P53/43/42. Reference: P53/43/42.

  7. Freeze Frame » South coast of Angmagssalik Island

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-135
    You are in:Title: South coast of Angmagssalik Island. Reference: P53/43/135. Reference: P53/43/135.

  8. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-425
    Reference: P53/43/425. Reference: P53/43/425. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).

  9. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-419
    Reference: P53/43/419. Reference: P53/43/419. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).

  10. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-441
    Reference: P53/43/441. Reference: P53/43/441. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).

  11. Freeze Frame » Coast from Long Island to Kangerdlugssuaq (20 August…

    https://www.freezeframe.ac.uk/collection/photos-british-arctic-air-route-expedition-1930-31/p53-43-424
    Reference: P53/43/424. Reference: P53/43/424. Title: Coast from Long Island to Kangerdlugssuaq (20 August 1930).

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