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1 - 50 of 124 search results for endogenous retrovirus where 3 match all words and 121 match some words.

  1. Fully-matching results

  2. PhD & postdoc Seminars | Wellcome-MRC Cambridge Stem Cell…

    https://www.stemcells.cam.ac.uk/events/phd-postdoc-seminars
    23 Feb 2024: Stephen Loughran, postdoc, Green lab. "JAK2 phosphorylates the RNA binding protein HNRNPA1 to repress endogenous retrovirus expression and protect haematopoiesis".

  3. Publications | Coleman Laboratory

    https://colemanlab.brc.cam.ac.uk/publications
    23 Feb 2024: 2020) Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. ... 2010) Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.

  4. Churchill College Alumnus awarded Humboldt Prize for World-leading…

    https://www.chu.cam.ac.uk/news/news-and-events/churchill-college-alumnus-awarded-humboldt-prize-for-world-leading-evolutionary-genetics-research/
    Thumbnail for Churchill College Alumnus awarded Humboldt Prize for World-leading Evolutionary Genetics Research - Churchill College 26 Mar 2024: I was wondering how to examine this and noticed something odd: several hundred copies of a fairly new (to our genome) endogenous retrovirus (ERV) were all active in early human embryos
    By: chuamychapman

  5. Results that match 1 of 2 words

  6. vsvg_pseudtyped_retrovirus_101209_0clip_image002.png | Ron Lab

    https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage002png
    23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image002.png. 2024 University of Cambridge.

  7. Yorgo Modis

    https://www.citiid.cam.ac.uk/yorgo-modis/
    23 Feb 2024: Key Research Questions. How do cells distinguish pathogenic viral nucleic acids from non-pathogenic endogenous nucleic acids? ... Pathogenic viral and non-pathogenic endogenous nucleic acids are often difficult to distinguish.

  8. Home - Professor Morrell's Group

    https://www.med.cam.ac.uk/morrell/
    23 Feb 2024: Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary

  9. Dr Li's Group

    https://www.med.cam.ac.uk/li/
    23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity.

  10. Prof Anthony Davenport | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/adavenport
    23 Feb 2024: In first in human, proof of principle studies, MM07 was a more efficacious dilator in human forearm and hand vein via the G-protein mediated pathway than the endogenous peptides. ... and Maguire, J,J. (2017) [Pyr. 1. ]Apelin-13. (1-12). is a biologically

  11. BHF Oxbridge CRM Introduction | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/research/oxbridgecrm
    23 Feb 2024: To harness the capacity of endogenous stem cell and progenitor cells for repair and regeneration.

  12. John Sinclair

    https://www.citiid.cam.ac.uk/john-sinclair/
    23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Site Search. Site Search. John Sinclair. Cambridge Institute of Therapeutic Immunology & Infectious

  13. Nicole C Kaneider

    https://www.citiid.cam.ac.uk/nicole-kaneider/
    22 Feb 2024: However, GPR35’s endogenous, relevant ligands and the receptor’s function remain enigmatic. We recently discovered that GPR35 regulates the cell’s ion homeostasis, its metabolic and proliferative activity by interacting

  14. Publications - Professor Bennett's Group

    https://www.med.cam.ac.uk/bennett/publications/
    23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Professor Bennett's Group. Publications. Links. 2024 University of Cambridge.

  15. Irene Cimino - Institute of Metabolic Science-Metabolic Research…

    https://www.mrl.ims.cam.ac.uk/irene-cimino/
    23 Feb 2024: Activation of the Hypothalamic-Pituitary-Adrenal axis by exogenous and endogenous GDF15. PNAS July 6, 2021, 118 (27) e2106868118;.

  16. Dr Fotios Sampaziotis | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/pi/sampaziotis
    23 Feb 2024: endogenous regeneration as a therapeutic strategy to repair duct damage. ... We are trying to understand why this mechanism fails in disease and identify therapeutics modifying the cells’ microenvironment to promote endogenous regeneration.

  17. Loraine Tung - Institute of Metabolic Science-Metabolic Research…

    https://www.mrl.ims.cam.ac.uk/loraine-tung/
    23 Feb 2024: 2021) Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15.

  18. DiscoverX European GPCR Symposium 2016 - 12 April - School of…

    https://www.medschl.cam.ac.uk/gpcr-symposium-12-april/
    23 Feb 2024: Dr Elizabeth M Rosethorne, Snr Research Fellow, University of Nottingham. Identification of Endogenous and Surrogate Ligands for Orphan GPCRs – Through Computational Drug Design Methods.

  19. Debra Rimmington - Institute of Metabolic Science-Metabolic Research…

    https://www.mrl.ims.cam.ac.uk/debra-rimmington/
    23 Feb 2024: Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proc Natl Acad Sci U S A.

  20. Poster Abstracts | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/poster-abstracts
    23 Feb 2024: Background: The apelin receptor, a class A GPCR, binds two endogenous peptide ligands, apelin and ELA, to induce potent vasodilatation and increase cardiac output. ... Considering these limitations, we are developing a novel method for stimulating

  21. https://www.medschl.cam.ac.uk/tag/hormones/feed/

    https://www.medschl.cam.ac.uk/tag/hormones/feed/
    23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute

  22. LMB Fellows - MRC Laboratory of Molecular Biology

    https://www2.mrc-lmb.cam.ac.uk/group-leaders/lmb-fellows/
    Thumbnail for LMB Fellows - MRC Laboratory of Molecular Biology 23 Apr 2024: His application of forward-genetic screens discovered the Human Silencing Hub ‘HUSH’, the critical transcriptional epigenetic repressor complex for silencing both newly integrated retroviruses and mobile endogenous retrotransposons.
    By: @MRC_LMB

  23. Dr William McEwan | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/william
    23 Feb 2024: Person keywords:. neutralisation. adenovirus. retrovirus. virus. intracellular immunity. antibody. Contact us.

  24. Cambridge Clinical Multiple Sclerosis Research

    https://www-neurosciences.medschl.cam.ac.uk/cambridge-clinical-ms-research/
    23 Feb 2024: Investigating natural remyelination in people with MS. Doing clinical trials to identify drugs which promote endogenous remyelination in people with MS.

  25. vsvg_pseudtyped_retrovirus_101209_0clip_image004.png | Ron Lab

    https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage004png
    23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image004.png. 2024 University of Cambridge.

  26. Dr Wei Li | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/wli
    23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity.

  27. Research

    https://www.med.cam.ac.uk/li/research/
    23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity.

  28. Publications - Professor Morrell's Group

    https://www.med.cam.ac.uk/morrell/publications/
    23 Feb 2024: Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary

  29. Dr Janet Maguire | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/jmaguire
    23 Feb 2024: Pyr. 1. ]apelin-13. (1-12). is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr. ... Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration

  30. Robyn Macrae | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/robyn-macrae
    23 Feb 2024: Title: The apelin signalling system is composed of the G-protein coupled apelin receptor and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). ... Structure and pharmacology of the apelin receptor with a recommendation that

  31. Dr Andrew Sage | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/asage
    23 Feb 2024: Recently, our lab defined the direct overall contribution of endogenous antibodies to atherosclerosis in a fully immunocompetent model.

  32. Professor Robert Glen | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/rglen
    23 Feb 2024: FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes.

  33. Professor Guy Brown | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/gbrown
    23 Feb 2024: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.

  34. Professor Colin Taylor | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/ctaylor
    23 Feb 2024: Endogenous signalling pathways and caged-IP. 3. evoke Ca. 2+. puffs at the same abundant immobile intracellular sites.

  35. https://www.medschl.cam.ac.uk/tag/endocrinology/feed/

    https://www.medschl.cam.ac.uk/tag/endocrinology/feed/
    23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute

  36. The power of hormones on the world’s trading floors - School of…

    https://www.medschl.cam.ac.uk/power-hormones-worlds-trading-floors/
    23 Feb 2024: By using personalised dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell

  37. Professor Paul Lehner | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/lehner
    23 Feb 2024: Remarkably HUSH also silences endogenous mobile retrotransposons like LINE-1 elements, which make up 17% of our genome.

  38. Publications - Clinical Gerontology

    https://www.phpc.cam.ac.uk/gerontology/publications/
    23 Feb 2024: Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition ( EPIC ). Endocr Relat Cancer. 2008 Jun;15(2):485-497. Rohrmann S, Linseisen ... Endogenous androgens and risk of epithelial

  39. Professor Jon Yewdell | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/yewdell
    23 Feb 2024: 2012). MHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. ... 2012). Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters.

  40. Joshua Bernstock | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/bernstock
    23 Feb 2024: Endogenous NPCs subsequently migrate toward the ischemic lesion where they promote tissue remodeling and neural repair. ... restorative responses initially executed by the endogenous NPC population. We claim that understanding these immunomodulatory

  41. Dr Nicholas Matheson | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/njm25%40cam.ac.uk
    23 Feb 2024: host-pathogen interaction. proteomics. retrovirus. immunobiology. SILAC. metabolism. Contact us. Cambridge Immunology Network Coordinator.

  42. Professor Jonathan Luke Heeney | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/heeney
    23 Feb 2024: virology. innate immunity. retrovirus. Immunosenescence. Calcivirus RNA viruses. Immune-ageing. Contact us.

  43. Dr Joseph Cheriyan | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/jcheriyan
    23 Feb 2024: Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13.

  44. https://www.cardiovascular.cam.ac.uk/taxonomy/term/7/feed

    https://www.cardiovascular.cam.ac.uk/taxonomy/term/7/feed
    23 Feb 2024: Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous peptide ligand.

  45. https://www.cardiovascular.cam.ac.uk/taxonomy/term/30/feed

    https://www.cardiovascular.cam.ac.uk/taxonomy/term/30/feed
    23 Feb 2024: of metabolism in multiple species by endogenous enzymes.</a> Kirchmair J, Williamson MJ, Afzal AM, Tyzack JD, Choy AP, Howlett A, Rydberg P, <b>Glen RC</b>.<span class="jrnl"

  46. Anthony Coll - Institute of Metabolic Science-Metabolic Research…

    https://www.mrl.ims.cam.ac.uk/research/principal-investigators/anthony-coll/
    23 Feb 2024: Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proc Natl Acad Sci U S A.

  47. Dr Anthony Davenport - EMIT

    https://emit.medschl.cam.ac.uk/people/investigators/dr-anthony-davenport/
    23 Feb 2024: The peptide apelin is the endogenous ligand for a novel G-protein coupled receptor with an emerging key role in cardiovascular disease. ... and Maguire, J,J. (2017) [Pyr. 1. ]Apelin-13. (1-12). is a biologically Active ACE2 Metabolite of the Endogenous

  48. On detection of ER stress | Ron Lab

    https://ron.cimr.cam.ac.uk/detection-er-stress
    23 Feb 2024: 2003 February; 23(4): 1292–1303) in which they report on the successful application of the SCBT anti-GADD34 H-193 serum to stain endogenous GADD34 in NIH 3T3 cells. ... We were unable to detect the endogenous XBP-1 with the SC-8015 monoclonal antiserum)

  49. Joe Herbert - John van Geest Centre for Brain Repair

    https://www.brc.cam.ac.uk/principal-investigators/joe-herbert/
    23 Feb 2024: Eur. J. Neursci. 27, 2493-500. Coates JM, Herbert J (2008) Endogenous steroids and financial risk taking on a London trading floor.

  50. Publications - Institute of Metabolic Science-Metabolic Research…

    https://www.mrl.ims.cam.ac.uk/research/publications/
    23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Site Search. Site Search. Publications. Institute of Metabolic Science-Metabolic Research Laboratories.

  51. https://www.cardiovascular.cam.ac.uk/taxonomy/term/33/feed

    https://www.cardiovascular.cam.ac.uk/taxonomy/term/33/feed
    23 Feb 2024: of metabolism in multiple species by endogenous enzymes.</a> Kirchmair J, Williamson MJ, Afzal AM, Tyzack JD, Choy AP, Howlett A, Rydberg P, <b>Glen RC</b>.<span class="jrnl"

  52. Professor Yorgo Modis | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/yorgo
    23 Feb 2024: Our key goals are to understand:. -how cells distinguish viral from endogenous nucleic acids.

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