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1 - 5 of 5 search results for p53

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  2. Genome-editing tool could increase cancer risk in cells, say…

    https://www.cam.ac.uk/research/news/genome-editing-tool-could-increase-cancer-risk-in-cells-say-researchers
    Thumbnail for Genome-editing tool could increase cancer risk in cells, say researchers | University of Cambridge 11 Jun 2018: Absence of p53 in cells makes them more likely to become tumorous as damage can no longer be corrected. ... The team found that by decreasing activity of p53 in a cell, they could more efficiently edit healthy cells.
    By: @cambridge_uni

  3. Uncovering how alcohol-derived metabolites damage the genome of stem…

    https://www2.mrc-lmb.cam.ac.uk/uncovering-alcohol-derived-metabolites-damage-genome-stem-cells/
    Thumbnail for Uncovering how alcohol-derived metabolites damage the genome of stem cells - MRC Laboratory of Molecular Biology 4 Jan 2018: This result suggests that the critically important p53 stress response in stem cells fundamentally differ from the response seen in other cells. ... In addition, the new insight into the function of p53 in blood stem cells may explain why certain blood
    By: pmabbs, @MRC_LMB

  4. MobiDB 3.0: more annotations for intrinsic disorder, conformational…

    www-vendruscolo.ch.cam.ac.uk/piovesan2018nar.pdf
    22 Apr 2018: D476 Nucleic Acids Research, 2018, Vol. 46, Database issue. Disorder and residual helicity alter p53-Mdm2 binding affinity andsignaling in cells.

  5. Submitted 16 March 2018Accepted 8 June 2018Published 4 July ...

    www-vendruscolo.ch.cam.ac.uk/papaleo2018pj.pdf
    23 Sep 2018: Submitted 16 March 2018Accepted 8 June 2018Published 4 July 2018. Corresponding authorKresten Lindorff-Larsen,lindorff@bio.ku.dk. Academic editorCamillo Rosano. Additional Information andDeclarations can be found onpage 16. DOI 10.7717/peerj.5125.

  6. A Rationally Designed Hsp70 Variant Rescues the…

    www-vendruscolo.ch.cam.ac.uk/bongiovanni2018ijms.pdf
    23 Sep 2018: International Journal of. Molecular Sciences. Article. A Rationally Designed Hsp70 Variant Rescues theAggregation-Associated Toxicity of Human IAPP inCultured Pancreatic Islet β-Cells. Marie Nicole Bongiovanni, Francesco Antonio Aprile ID , Pietro

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