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Opinion: Want to eradicate viruses? They made us who we are |…
https://www.cam.ac.uk/research/discussion/opinion-want-to-eradicate-viruses-they-made-us-who-we-are28 Feb 2017: While HIV infects immune cells, when a retrovirus instead infects the cells that produce eggs or sperm, the viral DNA can be inherited by any offspring. ... All these viruses which inserted into our DNA long ago are termed endogenous retroviruses (ERVs). Results that match 1 of 2 words
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Symbiont strain is the main determinant of variation in…
www.jiggins.gen.cam.ac.uk/pdfs/martinez2017.pdf9 Aug 2017: atpDQALL_R: 50-AATCCTTTATGAGCTTTTGC-30) relative to the. endogenous Drosophila control gene RpL32 (species-specific primers;. ... GGTTT-30; reverse: 50-CTTGAACCATGGCCTTTTG-30) relative to the. endogenous control gene RpL32 (species-specific primers; -
Pan-arthropod analysis reveals somatic piRNAs as an ancestral defence …
www.jiggins.gen.cam.ac.uk/pdfs/lewis2017.pdf5 Dec 2017: Virus identification and genome assembly. To identify viruses, we first mapped RNA-Seq reads to the genome of the host species to exclude genome-derived transcripts, thus filtering out endogenous viral ... Nat. Commun. 7, 13856 (2016). 9. Ghildiyal, M. -
on November 22, 2017http://rsif.royalsocietypublishing.org/Downloaded …
www.damtp.cam.ac.uk/user/lauga/papers/142.pdf22 Nov 2017: Direct visualizations [6] ofthe streaming flows (by means of endogenous tracer particles) and the micro-tubules (fluorescently labelled) show that the flows are disordered on the scaleof the oocyte and are -
on November 22, 2017http://rsif.royalsocietypublishing.org/Downloaded …
www.damtp.cam.ac.uk/user/gold/pdfs/filament_oscillations.pdf22 Nov 2017: Direct visualizations [6] ofthe streaming flows (by means of endogenous tracer particles) and the micro-tubules (fluorescently labelled) show that the flows are disordered on the scaleof the oocyte and are -
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www.damtp.cam.ac.uk/user/gold/pdfs/dynactin.pdf16 Oct 2017: phenotype. (D–E) Confocal images of fluorescent in situ hybridisations (FISH) to endogenous oskar mRNA in a. -
The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress…
www-vendruscolo.ch.cam.ac.uk/aprile2017sr.pdf17 Sep 2017: Cas9 system21 for disruption of endogenous expression of the DNAJB6 gene in HEK293T cells. ... B) Immunocytochemistry showing expression of the endogenous DNAJB6a and DNAJB6b forms in α-syn-DsRed HEK293T cells. -
REPORT◥ PROTEOSTASIS UBE2O is a quality control factor fororphans ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017b.pdf4 Aug 2017: Catalytically inactive UBE2O(C1040S) alsorecovered endogenous and exogenous RPL24(but no detectable ubiquitinated forms), whereasUBE2O(DCR2) interacted poorly with RPL24 (fig.S10D). ... The heterogeneity of ubiquitin bands in the samples with cytosol is -
REPORT◥ PROTEIN HOMEOSTASIS Mechanistic basis for a moleculartriage…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017.pdf19 Jan 2017: endogenous proteins with recombinant variantsrevealed the functional roles for all of the factorsand interactions. ... C) Immunoblots (IB) for triage components of control or BAG6 complex-depleted RRL replenished with recombinant BAG6 sub-complexes used -
Folate and formaldehyde: from vitamin to genotoxin to DNA building…
https://www2.mrc-lmb.cam.ac.uk/folate-and-formaldehyde-from-vitamin-to-genotoxin-to-dna-building-block/17 Aug 2017: They further showed that when the protection against this molecule is removed in mice then the levels of endogenous formaldehyde rise leading to overwhelming DNA damage and rapid death.
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