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What Darwin didn’t know: viruses and evolution | University of…
https://www.cam.ac.uk/research/news/what-darwin-didnt-know-viruses-and-evolution1 May 2009: Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are examples that have caused relatively silent epidemics, in some cases infecting hundreds of millions globally. ... One area of research in Professor Heeney’s lab -
https://www.anthroencyclopedia.com/taxonomy/term/611/feed
https://www.anthroencyclopedia.com/taxonomy/term/611/feed6 May 2024: p> <p>The virus causing AIDS (Acquired Immunodeficiency Syndrome), identified in the United States in 1981, spread to a slow pandemic, killing around 30 million people. ... the motto: ‘better a vaccine without a pandemic than a pandemic without a -
Ravindra Gupta
https://www.citiid.cam.ac.uk/ravindra-gupta/23 Feb 2024: The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity. ... Simian Immunodeficiency Virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by -
Synthetic biology: applications come of age
https://haseloff.plantsci.cam.ac.uk/resources/Part2SynBio_refs/Lecture-3/Khalil2010.pdf14 Aug 2023: Activation of the second gate input is the key to unlocking translation; specifically, translation can be induced when a second promoter (for example, P. ... coli-infected mice, potentiated killing of antibiotic-resistant bacteria and, importantly, -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed6 May 2024: br />5 European Vaccine Initiative (EVI), Heidelberg, Germany. <br />6 Babraham Bioinformatics Facility, Babraham Institute, Cambridge, UK. ... In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by -
RETROVIRUSES: KEEPING THE ENEMY CLOSER | Cambridge Infectious Diseases
https://www.infectiousdisease.cam.ac.uk/competitions/winners/retroviruses-keeping-the-enemy-closer6 May 2024: The much feared human immunodeficiency virus (HIV), a retrovirus responsible for acquired immunodeficiency syndrome (AIDS), is one of the most debilitating and ultimately fatal infectious diseases known to man. ... Using a genetically modified retrovirus -
PUBLICATIONS (Journals and contribution to books)
https://www.mrc-bsu.cam.ac.uk/wp-content/uploads/2014/03/SR-full-list-of-publications_2022.docx3 Aug 2022: de Hoogh, K. Gorog, P. Elliott. (2007). Down syndrome in births near landfill sites. ... Meningococcal disease and influenza-like syndrome : a new approach to an old question. -
TH ER AP EU TIC S S YM PO ...
https://www.milner.cam.ac.uk/wp-content/uploads/2019/07/milner_symposium_final.pdf23 Jul 2019: of diseases and syndromes such as infections, autoimmunity, irritable bowel syndromes and cancer. ... We have established human models of the aortic disease in MFS using patient-derived human induced pluripotent stem cells (hiPSCs). -
2012 – 2013 No.37 Wolfson ReviewThe The Wolfson Review ...
https://www.wolfson.cam.ac.uk/sites/default/files/2018-10/wolfson-review-web-2013.pdf29 Aug 2017: 2012 – 2013 No.37. Wolfson ReviewThe. The Wolfson Review. 2012 – 2013 N. o.37. Wolfson College Barton RoadCambridge CB3 9BB www.wolfson.cam.ac.uk. Published in 2013 by Wolfson College, Cambridge. Barton Road, Cambridge CB3 9BB. Wolfson College, -
https://www.path.cam.ac.uk/taxonomy/term/41/feed
https://www.path.cam.ac.uk/taxonomy/term/41/feed6 May 2024: She leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus.</p> <p>Her team develops new techniques to allow us to visualise better the -
Research News Archives - Page 8 of 29 - School of Clinical Medicine
https://www.medschl.cam.ac.uk/category/schoolnews/research-news/page/8/23 Feb 2024: model of the human immunodeficiency, Activated PI3Kinase δ syndrome (APDS). -
LectList2001
https://www.reporter.admin.cam.ac.uk/reporter/2001-02/special/01/p172-207.pdf28 Sep 2001: DR S. H. P. MADDRELLThe Living Cell. (Four lectures). PROF. D. J. ELLARMacromolecules in the Cell. (Five lectures). DR J. DAVIESMembranes: Molecular Superstructure. (Five lectures). DR K. JOHNSTONE AND DR K. V. BRINDLEEnergy and Biosynthesis. (Ten -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20951
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/20951nnnn. Human immunodeficiency virus type 1 (HIV-1) can cause persistent infections and result in acquired immunodeficiency syndrome (AIDS). -
Dr Helen Baxendale | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/baxendale23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating -
Professor Willem Ouwehand | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wouwehand23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS) -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/188/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/188/feed6 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/205/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/205/feed6 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory ... strong>This work has revealed key traits -
https://www.path.cam.ac.uk/taxonomy/term/17/feed
https://www.path.cam.ac.uk/taxonomy/term/17/feed6 May 2024: She leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus.</p> <p>Her team develops new techniques to allow us to visualise better the -
Okkenhaug | Magdalene College
https://www.magd.cam.ac.uk/user/okkenhaugIn recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that the inhibition of PI3Kδ paradoxically -
Scientists discover genetic disease which causes recurrent…
https://www.cam.ac.uk/research/news/scientists-discover-genetic-disease-which-causes-recurrent-respiratory-infections18 Oct 2013: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is -
https://www.path.cam.ac.uk/taxonomy/term/231/feed
https://www.path.cam.ac.uk/taxonomy/term/231/feed6 May 2024: The initial detection of a vaccine vector by the innate immune system has long lasting consequences for the development of memory responses. ... We use vaccinia virus, the vaccine that was developed to eradicate smallpox to help understand these -
CID Annual Symposium 2022 Programme: Flash Talks | Cambridge…
https://www.infectiousdisease.cam.ac.uk/cid-annual-symposium-2022-programme-flash-talks6 May 2024: Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis. Noémie Lefrancq, Department of Genetics. ... These novel insights into Bp dynamics and its interactions with vaccine-induced immunity are highly relevant to vaccination -
https://www.immunology.cam.ac.uk/taxonomy/term/64/feed
https://www.immunology.cam.ac.uk/taxonomy/term/64/feed23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests: </div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire -
https://www.path.cam.ac.uk/taxonomy/term/15/feed
https://www.path.cam.ac.uk/taxonomy/term/15/feed6 May 2024: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature 593, 136–141 (2021).</p> <p>• Kemp, S. ... Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 -
https://www.anthroencyclopedia.com/taxonomy/term/82/feed
https://www.anthroencyclopedia.com/taxonomy/term/82/feed6 May 2024: Open Encyclopedia of Anthropology - Environment https://www.anthroencyclopedia.com/entry-tags/environment en Infrastructure https://www.anthroencyclopedia.com/entry/infrastructure <div class="image"><img typeof="foaf:Image" -
https://www.anthroencyclopedia.com/taxonomy/term/221/feed
https://www.anthroencyclopedia.com/taxonomy/term/221/feed6 May 2024: Open Encyclopedia of Anthropology - Science & Technology https://www.anthroencyclopedia.com/entry-tags/science-technology en Race and racism https://www.anthroencyclopedia.com/entry/race-and-racism <div class="image"><img typeof="foaf:Image" -
https://www.anthroencyclopedia.com/taxonomy/term/172/feed
https://www.anthroencyclopedia.com/taxonomy/term/172/feed6 May 2024: Open Encyclopedia of Anthropology - Care https://www.anthroencyclopedia.com/entry-tags/care en Surveillance https://www.anthroencyclopedia.com/entry/surveillance <div class="image"><img typeof="foaf:Image" -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/46/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/46/feed6 May 2024: Timing of initiation of antiretroviral therapy in human immunodeficiency virus (HIV)-associated tuberculous meningitis. -
https://www.med.cam.ac.uk/nejentsev/wp-json/wp/v2/pages/6
https://www.med.cam.ac.uk/nejentsev/wp-json/wp/v2/pages/623 Feb 2024: {"id":6,"date":"2011-03-01T11:55:15","date_gmt":"2011-03-01T11:55:15","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=6"},"modified":"2015-02-24T14:33:58","modified_gmt":"2015-02-24T14:33:58","slug":"research","status":"publ -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/89/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/89/feed6 May 2024: Cushing's</p> <p>syndrome and adrenal axis suppression in a patient treated with ritonavir and</p> <p>corticosteroid eye drops. ... span>. Vaccine preventable diseases in returned international</p> <p>travelers: results from the GeoSentinel Surveillance -
Dr Rachael Bashford-Rogers | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/rachaelbf23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution -
https://www.path.cam.ac.uk/taxonomy/term/9/feed
https://www.path.cam.ac.uk/taxonomy/term/9/feed6 May 2024: Contrasting effects of linezolid on healthy and dysfunctional human neutrophils: reducing C5a-induced injury. ... Monocytes control second-phase neutrophil emigration in established LPS-induced murine lung injury. -
The Academy of Medical Sciences announces election of new Fellows…
https://www.cam.ac.uk/research/news/the-academy-of-medical-sciences-announces-election-of-new-fellows-202112 May 2021: the process by which new variants likely arise, and also reporting the first data on Pfizer BioNTech vaccine-induced antibody responses against the B.1.1.7 ‘Kent UK’ variant. ... His research investigates the basis for pathological immune activation -
https://www.phar.cam.ac.uk/taxonomy/term/5/feed
https://www.phar.cam.ac.uk/taxonomy/term/5/feed6 May 2024: and Biswas, S., 2022. <i>Modular capsid decoration boosts adenovirus vaccine-induced humoral immunity against SARS-CoV-2. ... and Howarth, M., 2019. <i>SnoopLigase peptide-peptide conjugation enables modular vaccine assembly. -
Julia Kenyon
https://www.homerton.cam.ac.uk/people/julia-kenyonShe leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus. ... Viruses 3(11) 2192-2213. Kenyon JC, Lever AML (2011) XMRV, Prostate Cancer and Chronic Fatigue Syndrome. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed6 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
Professor Willem H Ouwehand - Department of Haematology
https://www.haem.cam.ac.uk/staff/senior-staff/professor-willem-h-ouwehand/23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed6 May 2024: Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. 2019. Cell Metabolism. ... Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing. -
Dr Sara Lear | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/sara.lear%40nhs.net23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed6 May 2024: CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. ... 2009). Multiple redundant stress resistance mechanisms are induced i<i>n Salmonella enterica </i>serovar Typhimurium<i> </i>in response to modulation -
Dr Edward Banham-Hall | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/banham-hall23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS. -
Discovery of the genetic basis of a rare immune disease - MRC…
https://www2.mrc-lmb.cam.ac.uk/discovery-of-the-genetic-basis-of-a-rare-immune-disease/22 Oct 2013: The researchers first examined genetic information from individuals who suffer from immunodeficiency and are predisposed to infections. ... The newly identified disease has been called Activated PI3K-δ Syndrome (APDS) after the enzyme that is affected -
https://www.path.cam.ac.uk/taxonomy/term/7/feed
https://www.path.cam.ac.uk/taxonomy/term/7/feed6 May 2024: 29875319.pdf" target="_blank">[PDF]</a></p> <p><a href="http://www.ncbi.nlm.nih.gov/pubmed/29540581" target="_blank"><b>Bach2 Promotes B Cell Receptor-Induced Proliferation of B Lymphocytes ... ncbi.nlm.nih.gov/pubmed/28530713" target="_blank"><b>BACH2 -
Member: Anna Jane Dreyer - Cambridge Neuroscience
https://neuroscience.cam.ac.uk/member/annajanedreyer1/My current project involves investigating the role of socioeconomic inequalities in the dementia syndromes associated with frontotemporal lobar degeneration and Parkinson's disease. ... Moving on From HAND: Why We Need New Criteria for Cognitive -
Professor Gillian M Griffiths FMedSci, FRS | Cambridge Immunology…
https://www.immunology.cam.ac.uk/Networkdirectory/gg305%40cam.ac.uk23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome. -
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. -
Publications - Genetic and functional mechanisms of susceptibility to …
tb.med.cam.ac.uk/publications-2/Durandy A. #. (. #. corresponding authors):Occurrence of B-cell lymphomas in patients with activated phosphoinositide 3-kinase δ syndrome. ... A, Doffinger R, Gilmour KC, Henriquez F, Thrasher AJ, Gaspar HB, Nejentsev S:Immunodeficiency and disseminated -
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/
https://www.psychiatry.cam.ac.uk/blog/tag/research-2/feed/16 Feb 2024: An investigation of RF networks and RF mean levels/p pApril Le: Neurophysiological biomarkers of dementia in Down Syndrome/p pSharon Neufeld: Does mental health treatment promote family functioning to mitigate ... of change/p pLucie Aman: Markers of risk -
tb.med.cam.ac.uk/feed/
tb.med.cam.ac.uk/feed/25 Jun 2015: protecting from infection./p pstrongGenetic analyses of patients with Primary Immunodeficiencies/strong/p pPrimary Immunodeficiencies (PIDs) comprise a heterogeneous group of genetic disorders that affect functioning of the immune system and -
Scientists discover genetic disease which causes recurrent…
https://www.med.cam.ac.uk/blog/scientists-discover-genetic-disease-which-causes-recurrent-respiratory-infections/23 Feb 2024: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is
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