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Topics | University of Cambridge
https://www.cam.ac.uk/topics12 May 2024: Search. Search. Topics. Topics.. The demand continues for materials that are stronger, cheaper, lighter, more conductive – simply better. Cambridge researchers have long worked with African colleagues on issues that matter not just to the -
Cambridge-Africa Activity Map :: Cambridge-Africa
https://www.cambridge-africa.cam.ac.uk/initiatives/project-map/Functional studies of a potential blood stage malaria vaccine candidate. Dr Julian C. ... Contribution of strain diversity to rotavirus vaccine effectiveness in Ghana: Investigating human rotavirus reservoirs and strain diversity in farm animals. -
THRiVE Fellows and Alumni Publications :: Cambridge-Africa
https://www.cambridge-africa.cam.ac.uk/initiatives/training-programmes/thrive/cambridge-africa-fellows-publications-3/Cambridge-Africa. » Initiatives » Previous Initiatives » THRiVE Cambridge (2009 to 2022) » THRiVE Fellows and Alumni Publications. THRiVE Fellows and Alumni Publications. THRiVE. 2021. Faust CL, Brunker K, Ajambo D, Ryan M, Moses A, Rowel C, -
Professor Willem Ouwehand | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wouwehand23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS) -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/51/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/51/feed23 Feb 2024: Cambridge Cardiovascular - Wellcome Sanger Institute https://www.cardiovascular.cam.ac.uk/institutions/dir-sanger en Jack Palmer https://www.cardiovascular.cam.ac.uk/staff/jack-palmer <div class="field field-name-body field-type-text-with-summary -
DOI: 10.1126/science.1254704, 1558 (2014);345 Science Georgina M.…
https://www.cfse.cam.ac.uk/system/files/documents/background_jan_2015_paper_2_mace.pdfThe three best-characterized. monogenic autoimmune dis-. orders are autoimmune poly-. endocrinopathy syndrome. ... autoimmunity (8). The field of primary immunodeficiencies. has also diversified considerably in terms. -
School of Clinical Medicine Cambridge Institute for Medical Research…
https://www.cimr.cam.ac.uk/files/cimr_anniversary_research_report_2018_web.pdf23 Jun 2021: We also use genetic approaches, including studies on primary immunodeficiencies and genetic screens including the immunophenotyping (3i) consortium (http://www.immunophenotype.org/). ... galactocerebrosidase and iduronate sulphatase implicated in the -
Ravindra Gupta
https://www.citiid.cam.ac.uk/ravindra-gupta/23 Feb 2024: The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity. ... Simian Immunodeficiency Virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by -
https://www.citiid.cam.ac.uk/wp-json/wp/v2/pages/7145
https://www.citiid.cam.ac.uk/wp-json/wp/v2/pages/7145The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity./pnpRavi Gupta is a co-opted member ... strongAge-related immune response heterogeneity to SARS-CoV-2 -
Prof Pietro Liò | Department of Computer Science and Technology
https://www.cst.cam.ac.uk/people/pl21912 May 2024: Wei, X., Pu, C., He, Z. and Lio, P., 2021. Deep Reinforcement Learning-based Vaccine Distribution Strategies Proceedings - 2021 2nd International Conference on Electronics, Communications and Information Technology, CECIT 2021,. -
Professor Willem H Ouwehand - Department of Haematology
https://www.haem.cam.ac.uk/staff/senior-staff/professor-willem-h-ouwehand/23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95. -
Julia Kenyon
https://www.homerton.cam.ac.uk/people/julia-kenyonShe leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus. ... Viruses 3(11) 2192-2213. Kenyon JC, Lever AML (2011) XMRV, Prostate Cancer and Chronic Fatigue Syndrome. -
© 2006 Microsoft Corporation. All rights reserved. TOW AR ...
https://www.ifm.eng.cam.ac.uk/uploads/Research/CTM/Roadmapping/computational_science.pdf13 Mar 2012: 2006 Microsoft Corporation. All rights reserved. TOW. AR. DS. 20. 20. SC. IEN. CE. Rosalind Franklin (1920-1958). James Watson, Francis Crick andMaurice Wilkins shared the 1962 NobelPrize in Physiology or Medicine for thediscovery of the -
Dr Edward Banham-Hall | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/banham-hall23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS. -
Dr Helen Baxendale | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/baxendale23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating -
Professor Gillian M Griffiths FMedSci, FRS | Cambridge Immunology…
https://www.immunology.cam.ac.uk/Networkdirectory/gg305%40cam.ac.uk23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome. -
Professor Jonathan Luke Heeney | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/heeney23 Feb 2024: Search site. Cambridge Immunology Network. Professor Jonathan Luke Heeney. Vaccine induced immunity. ... Immune correlates of natural and vaccine induced immunity. Viral evasion of host responses. -
Dr Rachael Bashford-Rogers | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/rachaelbf23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution -
Dr Rainer Döffinger | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/rainer.doffinger%40cam.ac.uk23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38. ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. -
Dr Sara Lear | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/sara.lear%40nhs.net23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe -
https://www.immunology.cam.ac.uk/taxonomy/term/11/feed
https://www.immunology.cam.ac.uk/taxonomy/term/11/feed23 Feb 2024: Cambridge Immunology Network - Immunogenetics https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/immunogenetics The complex effects of genotype on phenotype in immunology Every immunologist makes use of genetics at some level but the -
https://www.immunology.cam.ac.uk/taxonomy/term/17/feed
https://www.immunology.cam.ac.uk/taxonomy/term/17/feed23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require -
https://www.immunology.cam.ac.uk/taxonomy/term/25/feed
https://www.immunology.cam.ac.uk/taxonomy/term/25/feed23 Feb 2024: Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. ... Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity. -
https://www.immunology.cam.ac.uk/taxonomy/term/40/feed
https://www.immunology.cam.ac.uk/taxonomy/term/40/feed23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... blank">Simian Immunodeficiency Virus envelope glycoprotein -
https://www.immunology.cam.ac.uk/taxonomy/term/43/feed
https://www.immunology.cam.ac.uk/taxonomy/term/43/feed23 Feb 2024: JA, Lehner PJ (2014) TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. ... and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study.<span>Lancet</span>. -
https://www.immunology.cam.ac.uk/taxonomy/term/64/feed
https://www.immunology.cam.ac.uk/taxonomy/term/64/feed23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests: </div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire -
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed
https://www.immunology.cam.ac.uk/taxonomy/term/921/feed23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency. -
CID Annual Symposium 2022 Programme: Flash Talks | Cambridge…
https://www.infectiousdisease.cam.ac.uk/cid-annual-symposium-2022-programme-flash-talks12 May 2024: Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis. Noémie Lefrancq, Department of Genetics. ... These novel insights into Bp dynamics and its interactions with vaccine-induced immunity are highly relevant to vaccination -
RETROVIRUSES: KEEPING THE ENEMY CLOSER | Cambridge Infectious Diseases
https://www.infectiousdisease.cam.ac.uk/competitions/winners/retroviruses-keeping-the-enemy-closer12 May 2024: The much feared human immunodeficiency virus (HIV), a retrovirus responsible for acquired immunodeficiency syndrome (AIDS), is one of the most debilitating and ultimately fatal infectious diseases known to man. ... Using a genetically modified retrovirus -
Dr Effrossyni Gkrania - Klotsas MD, MPH, FRCP, PhD | Cambridge…
https://www.infectiousdisease.cam.ac.uk/directory/eg318%40cam.ac.uk12 May 2024: Cushing's. syndrome and adrenal axis suppression in a patient treated with ritonavir and. ... Surveillance Network. Vaccine preventable diseases in returned international. travelers: results from the GeoSentinel Surveillance Network. -
Professor Klaus Okkenhaug | Cambridge Infectious Diseases
https://www.infectiousdisease.cam.ac.uk/directory/ko256%40cam.ac.uk12 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
HIV | Cambridge Infectious Diseases
https://www.infectiousdisease.cam.ac.uk/research/active-research-projects/hiv12 May 2024: Cytomegalovirus (CMV) is responsible for the most common viral opportunistic infection in persons with acquired immunodeficiency virus syndrome (AIDS). ... University of Cambridge research paves way for effective HIV vaccine (Oct 2017, Heeney). -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/100/feed12 May 2024: CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. ... 2009). Multiple redundant stress resistance mechanisms are induced i<i>n Salmonella enterica </i>serovar Typhimurium<i> </i>in response to modulation -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/181/feed12 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/187/feed12 May 2024: Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. 2019. Cell Metabolism. ... Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing. -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/188/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/188/feed12 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/205/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/205/feed12 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory ... strong>This work has revealed key traits -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/46/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/46/feed12 May 2024: Cambridge Infectious Diseases - Addenbrooke's Hospital https://www.infectiousdisease.cam.ac.uk/departments/addenbrookes-hospital en Dr John Clark https://www.infectiousdisease.cam.ac.uk/staff/dr-john-clark <div class="field field-name-body field-type -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed12 May 2024: br />5 European Vaccine Initiative (EVI), Heidelberg, Germany. <br />6 Babraham Bioinformatics Facility, Babraham Institute, Cambridge, UK. ... In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/77/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/77/feed12 May 2024: Cushing's</p> <p>syndrome and adrenal axis suppression in a patient treated with ritonavir and</p> <p>corticosteroid eye drops. ... span>. Vaccine preventable diseases in returned international</p> <p>travelers: results from the GeoSentinel Surveillance -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/89/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/89/feed12 May 2024: Cushing's</p> <p>syndrome and adrenal axis suppression in a patient treated with ritonavir and</p> <p>corticosteroid eye drops. ... span>. Vaccine preventable diseases in returned international</p> <p>travelers: results from the GeoSentinel Surveillance -
Cyber Catastrophe
https://www.jbs.cam.ac.uk/wp-content/uploads/2020/08/141120-riskbriefing-ebolaandpandemicrisk-slides.pdf9 Jul 2023: 2002 Severe Acute Respiratory Syndrome. SARS. 1981-today Acquired Immunodeficiency Syndrome. HIV/AIDS. ... Vaccine Arrives! 11/20/2014 46. Getting Back to Business. 47. Headline Death Toll. -
Cambridge Centre for Risk StudiesCambridge Risk Framework Human…
https://www.jbs.cam.ac.uk/wp-content/uploads/2020/08/crs-sao-paolo-virus-pandemic.pdf9 Jul 2023: Racing to produce a vaccine. Until a vaccine is available, there is nothing to prevent the spread. ... Vaccine production methods are also time-consuming. Conventional techniques require the incubation of a vaccine dose . -
2021 年 3 月,第三期 Third Issue, March 2021 CHINA ...
https://www.jbs.cam.ac.uk/wp-content/uploads/2021/04/china-report-2020-issue-3.pdf9 Jul 2023: 2021 年 3 月,第三期. Third Issue, March 2021. CHINA REPORT. 中国报告 Originated and Selected by China Advisory Council. 中国顾问理事会撰选. -
HIV and AIDS — Corpus Christi JCR
https://www.jcr.corpus.cam.ac.uk/hiv-and-aidsWhat is it? HIV stands for Human Immunodeficiency Virus. When a person is HIV positive, infectious viruses can be found in their blood, semen, vaginal fluids, and breast milk. ... AIDS stands for Acquired Immunodeficiency Syndrome. Because of their weak -
Okkenhaug | Magdalene College
https://www.magd.cam.ac.uk/user/okkenhaugIn recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that the inhibition of PI3Kδ paradoxically -
Scientists discover genetic disease which causes recurrent…
https://www.med.cam.ac.uk/blog/scientists-discover-genetic-disease-which-causes-recurrent-respiratory-infections/23 Feb 2024: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is -
DecipherBILU - Dr Nejentsev's Group
https://www.med.cam.ac.uk/nejentsev/decipherbilu/23 Feb 2024: Project number: 657633. Project acronym: DecipherBILU. Project title: Understanding functional mechanisms leading to the BILU syndrome. ... Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders often caused by monogenic mutations that -
Research - Dr Nejentsev's Group
https://www.med.cam.ac.uk/nejentsev/research/23 Feb 2024: Genetic analyses of patients with Primary Immunodeficiencies. Primary Immunodeficiencies (PIDs) comprise a heterogeneous group of genetic disorders that affect functioning of the immune system and manifest as severe and/or recurrent ... Recently, we -
https://www.med.cam.ac.uk/nejentsev/wp-json/oembed/1.0/embed?url=https…
https://www.med.cam.ac.uk/nejentsev/wp-json/oembed/1.0/embed?url=https%3A%2F%2Fwww.med.cam.ac.uk%2Fnejentsev%2Fdecipherbilu%2F&format=xmlmessage:"ready",secret:r},"")}}}}(window,document); </script> MARIE SKLODOWSKA-CURIE ACTIONS Project number: 657633 Project acronym: DecipherBILU Project title: Understanding functional mechanisms leading to the BILU syndrome Primary
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