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Okkenhaug | Magdalene College
https://www.magd.cam.ac.uk/user/okkenhaugIn recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that the inhibition of PI3Kδ paradoxically -
Publications - Genetic and functional mechanisms of susceptibility to …
tb.med.cam.ac.uk/publications-2/Durandy A. #. (. #. corresponding authors):Occurrence of B-cell lymphomas in patients with activated phosphoinositide 3-kinase δ syndrome. ... A, Doffinger R, Gilmour KC, Henriquez F, Thrasher AJ, Gaspar HB, Nejentsev S:Immunodeficiency and disseminated -
Professor Willem Ouwehand | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wouwehand23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS) -
Unexpected matrix protein rearrangements seen in structures from…
https://www2.mrc-lmb.cam.ac.uk/unexpected-matrix-protein-rearrangements-seen-in-structures-from-intact-hiv-1-virus/6 Aug 2021: Human immunodeficiency virus type 1 (HIV-1) can cause persistent infections and result in acquired immunodeficiency syndrome (AIDS). ... Despite many years of intensive study, there is currently no vaccine against HIV-1 and it continues to be a major -
DOI: 10.1126/science.1254704, 1558 (2014);345 Science Georgina M.…
https://www.cfse.cam.ac.uk/system/files/documents/background_jan_2015_paper_2_mace.pdfThe three best-characterized. monogenic autoimmune dis-. orders are autoimmune poly-. endocrinopathy syndrome. ... autoimmunity (8). The field of primary immunodeficiencies. has also diversified considerably in terms. -
Synthetic biology: applications come of age
https://haseloff.plantsci.cam.ac.uk/resources/Part2SynBio_refs/Collins2010_nrg2775.pdf14 Aug 2023: Activation of the second gate input is the key to unlocking translation; specifically, translation can be induced when a second promoter (for example, P. ... coli-infected mice, potentiated killing of antibiotic-resistant bacteria and, importantly, -
Lect List 2008 215309
https://www.reporter.admin.cam.ac.uk/reporter/2008-09/special/01/pdfs/nat_sci_2.pdf18 Sep 2008: CHATTERJEECushing’s syndrome. (Case study) F. 23 Jan. PROF. V. P. COLLINSMitochondrial encephalomyopathies. ... RASSLLung cancer. W. 26 Nov. DR R. RINTOULLambert-Eaton syndrome. (Case study) W. -
https://www.path.cam.ac.uk/taxonomy/term/15/feed
https://www.path.cam.ac.uk/taxonomy/term/15/feed10 May 2024: Sensitivity of SARS-CoV-2 B.1.1.7 to mRNA vaccine-elicited antibodies. Nature 593, 136–141 (2021).</p> <p>• Kemp, S. ... Diffuse White Matter Signal Abnormalities on Magnetic Resonance Imaging Are Associated With Human Immunodeficiency Virus Type 1 -
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed
https://www.infectiousdisease.cam.ac.uk/taxonomy/term/50/feed10 May 2024: br />5 European Vaccine Initiative (EVI), Heidelberg, Germany. <br />6 Babraham Bioinformatics Facility, Babraham Institute, Cambridge, UK. ... In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by -
The Academy of Medical Sciences announces election of new Fellows…
https://www-neurosciences.medschl.cam.ac.uk/blog/the-academy-of-medical-sciences-announces-election-of-new-fellows-2021/23 Feb 2024: the process by which new variants likely arise, and also reporting the first data on Pfizer BioNTech vaccine-induced antibody responses against the B.1.1.7 ‘Kent UK’ variant. ... His research investigates the basis for pathological immune activation
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