Search

11 May 2024: Search. Search. Topics. Topics.. The demand continues for materials that are stronger, cheaper, lighter, more conductive – simply better. Cambridge researchers have long worked with African colleagues on issues that matter not just to the

Functional studies of a potential blood stage malaria vaccine candidate. Dr Julian C. ... Contribution of strain diversity to rotavirus vaccine effectiveness in Ghana: Investigating human rotavirus reservoirs and strain diversity in farm animals.

Cambridge-Africa. » Initiatives » Previous Initiatives » THRiVE Cambridge (2009 to 2022) » THRiVE Fellows and Alumni Publications. THRiVE Fellows and Alumni Publications. THRiVE. 2021. Faust CL, Brunker K, Ajambo D, Ryan M, Moses A, Rowel C,

23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS)

23 Feb 2024: Cambridge Cardiovascular - Wellcome Sanger Institute https://www.cardiovascular.cam.ac.uk/institutions/dir-sanger en Jack Palmer https://www.cardiovascular.cam.ac.uk/staff/jack-palmer <div class="field field-name-body field-type-text-with-summary

The three best-characterized. monogenic autoimmune dis-. orders are autoimmune poly-. endocrinopathy syndrome. ... autoimmunity (8). The field of primary immunodeficiencies. has also diversified considerably in terms.

23 Jun 2021: We also use genetic approaches, including studies on primary immunodeficiencies and genetic screens including the immunophenotyping (3i) consortium (http://www.immunophenotype.org/). ... galactocerebrosidase and iduronate sulphatase implicated in the

23 Feb 2024: The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity. ... Simian Immunodeficiency Virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by

The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity./pnpRavi Gupta is a co-opted member ... strongAge-related immune response heterogeneity to SARS-CoV-2

11 May 2024: and Almajhdi, FN., 2023. Immunoinformatics design of multivalent epitope vaccine against monkeypox virus and its variants using membrane-bound, enveloped, and extracellular proteins as targets. ... and GO-DS21 Consortium, , 2022. Diabetes and Obesity in

23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95.

She leads and collaborates in research on HIV, FIV (feline immunodeficiency virus), dengue virus and influenza virus. ... Viruses 3(11) 2192-2213. Kenyon JC, Lever AML (2011) XMRV, Prostate Cancer and Chronic Fatigue Syndrome.

13 Mar 2012: 2006 Microsoft Corporation. All rights reserved. TOW. AR. DS. 20. 20. SC. IEN. CE. Rosalind Franklin (1920-1958). James Watson, Francis Crick andMaurice Wilkins shared the 1962 NobelPrize in Physiology or Medicine for thediscovery of the

23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS.

23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating

23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.

23 Feb 2024: Search site. Cambridge Immunology Network. Professor Jonathan Luke Heeney. Vaccine induced immunity. ... Immune correlates of natural and vaccine induced immunity. Viral evasion of host responses.

23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38. ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe

23 Feb 2024: Cambridge Immunology Network - Immunogenetics https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/immunogenetics The complex effects of genotype on phenotype in immunology Every immunologist makes use of genetics at some level but the

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require

23 Feb 2024: Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. ... Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... blank">Simian Immunodeficiency Virus envelope glycoprotein

23 Feb 2024: JA, Lehner PJ (2014) TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. ... and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study.<span>Lancet</span>.

23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests:&nbsp;</div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

11 May 2024: Global spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis. Noémie Lefrancq, Department of Genetics. ... These novel insights into Bp dynamics and its interactions with vaccine-induced immunity are highly relevant to vaccination

11 May 2024: The much feared human immunodeficiency virus (HIV), a retrovirus responsible for acquired immunodeficiency syndrome (AIDS), is one of the most debilitating and ultimately fatal infectious diseases known to man. ... Using a genetically modified retrovirus

11 May 2024: Cushing's. syndrome and adrenal axis suppression in a patient treated with ritonavir and. ... Surveillance Network. Vaccine preventable diseases in returned international. travelers: results from the GeoSentinel Surveillance Network.

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory

11 May 2024: Cytomegalovirus (CMV) is responsible for the most common viral opportunistic infection in persons with acquired immunodeficiency virus syndrome (AIDS). ... University of Cambridge research paves way for effective HIV vaccine (Oct 2017, Heeney).

11 May 2024: CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages. ... 2009). Multiple redundant stress resistance mechanisms are induced i<i>n Salmonella enterica </i>serovar Typhimurium<i> </i>in response to modulation

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory

11 May 2024: Epstein-Barr Virus Induced One-Carbon Metabolism Drives B-Cell Transformation. 2019. Cell Metabolism. ... Temporal proteomic analysis of BK polyomavirus infection reveals virus-induced G2 arrest and highly effective evasion of innate immune sensing.

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory

11 May 2024: In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that deletion of PI3Kδ in regulatory ... strong>This work has revealed key traits

11 May 2024: Cambridge Infectious Diseases - Addenbrooke's Hospital https://www.infectiousdisease.cam.ac.uk/departments/addenbrookes-hospital en Dr John Clark https://www.infectiousdisease.cam.ac.uk/staff/dr-john-clark <div class="field field-name-body field-type

11 May 2024: br />5 European Vaccine Initiative (EVI), Heidelberg, Germany. <br />6 Babraham Bioinformatics Facility, Babraham Institute, Cambridge, UK. ... In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by

11 May 2024: Cushing's</p> <p>syndrome and adrenal axis suppression in a patient treated with ritonavir and</p> <p>corticosteroid eye drops. ... span>. Vaccine preventable diseases in returned international</p> <p>travelers: results from the GeoSentinel Surveillance

11 May 2024: Cushing's</p> <p>syndrome and adrenal axis suppression in a patient treated with ritonavir and</p> <p>corticosteroid eye drops. ... span>. Vaccine preventable diseases in returned international</p> <p>travelers: results from the GeoSentinel Surveillance

9 Jul 2023: 2002 Severe Acute Respiratory Syndrome. SARS. 1981-today Acquired Immunodeficiency Syndrome. HIV/AIDS. ... Vaccine Arrives! 11/20/2014 46. Getting Back to Business. 47. Headline Death Toll.

9 Jul 2023: Racing to produce a vaccine. Until a vaccine is available, there is nothing to prevent the spread. ... Vaccine production methods are also time-consuming. Conventional techniques require the incubation of a vaccine dose .

9 Jul 2023: 2021 年 3 月，第三期. Third Issue, March 2021. CHINA REPORT. 中国报告 Originated and Selected by China Advisory Council. 中国顾问理事会撰选.

What is it? HIV stands for Human Immunodeficiency Virus. When a person is HIV positive, infectious viruses can be found in their blood, semen, vaginal fluids, and breast milk. ... AIDS stands for Acquired Immunodeficiency Syndrome. Because of their weak

In recent years, he has contributed to the description of a new primary immunodeficiency syndrome caused by activated PI3Kδ mutations (APDS) and his group demonstrated that the inhibition of PI3Kδ paradoxically

23 Feb 2024: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is

23 Feb 2024: Project number: 657633. Project acronym: DecipherBILU. Project title: Understanding functional mechanisms leading to the BILU syndrome. ... Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders often caused by monogenic mutations that

23 Feb 2024: Genetic analyses of patients with Primary Immunodeficiencies. Primary Immunodeficiencies (PIDs) comprise a heterogeneous group of genetic disorders that affect functioning of the immune system and manifest as severe and/or recurrent ... Recently, we

message:"ready",secret:r},"")}}}}(window,document); </script> MARIE SKLODOWSKA-CURIE ACTIONS Project number: 657633 Project acronym: DecipherBILU Project title: Understanding functional mechanisms leading to the BILU syndrome Primary