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11 Jun 1997: Phosphoinositide-specific phospholipase C: structural basisfor catalysis and regulatory interactionsMatilda Katan and Roger L. Williams. Phosphoinositide-specific phospholipase C (PI-PLC) isozymeshave an important role in cellular responses to a

15 Jan 1998: Structural and Mechanistic Comparison of Prokaryoticand Eukaryotic Phosphoinositide-specificPhospholipases C. Dirk W. Heinz1, Lars-Oliver Essen2 and Roger L. Williams3. 1Institut fuÈ r OrganischeChemie und BiochemieUniversitaÈt

6 May 1999: Article No. jmbi.1999.2720 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 288, 649657. Crystal Structure of the Two N-terminal Domains ofg3p from Filamentous Phage fd at 1.9 AÊ : Evidence forConformational Lability. Philipp

7 Jul 1999: Article No. jmbi.1999.2910 available online at http://www.idealibrary.com on J. Mol. Biol. (1999) 290, 867879. The Structure of a Tunicate C-type Lectin fromPolyandrocarpa misakiensis Complexed withD-Galactose. Se bastien F. Poget1, Glen B. Legge1,

11 Nov 1999: 1999 Macmillan Magazines Ltd. letters to nature. NATURE | VOL 402 | 18 NOVEMBER 1999 | www.nature.com 313. 12. Macleod, K. F. et al. p53-dependent and independent expression of p21 during cell growth,. differentiation, and DNA damage. Genes Dev. 9,

6 Jun 2000: "# $. %! & ' () & ,! & ,! " # $ % # & # ' # & & & & # '! - - - -. ,! / 0012+ 3! )! , , 4! , / 005 002+ 3! /62! 3! 78& & &78& & /9) 00%2+ 3! &! & ' /! 82 - /! 8%2+ 8 &! : ,)! )! 78! &! & 3! )! & 4 ; & 9 /2 ,)! & 6 )! )! & /9) 00%2+ ) )! < /= 00>2+.

1 Dec 2000: Cell, Vol. 103, 931–943, December 8, 2000, Copyright 2000 by Cell Press. Crystal Structure and Functional Analysisof Ras Binding to Its EffectorPhosphoinositide 3-Kinase g. suppression of apoptosis (Franke et al., 1997), reorgani-zation of the

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

15 Feb 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2001. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 90,151 Agricultural. 1,080,736Rates. 13,243 Urban not on building leases. 14,545,748Agency,

20 Apr 2002: Calcium-dependent Membrane Penetration Is a Hallmark of theC2 Domain of Cytosolic Phospholipase A2 Whereas the C2A Domainof Synaptotagmin Binds Membranes Electrostatically. (Received for publication, May 21, 1998). Bazbek Davletov‡, Olga Perisic,

20 Apr 2002: Proc. Natl. Acad. Sci. USAVol. 94, pp. 9637–9642, September 1997Biophysics. The 2.0-Å resolution crystal structure of a trimeric antibodyfragment with noncognate VH–VL domain pairs shows arearrangement of VH CDR3XUE Y. PEI, PHILIPP HOLLIGER,

20 Apr 2002: Crystal Structure of a Calcium-Phospholipid Binding Domainfrom Cytosolic Phospholipase A2. (Received for publication, September 24, 1997). Olga Perisic‡, Sun Fong, Denise E. Lynch‡, Mark Bycroft, and Roger L. Williams‡. From the ‡Medical

20 Apr 2002: Review. Mammalian phosphoinositide-speci¢c phospholipase C. Roger L. Williams Medical Research Council Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK. Received 1 April 1999 ; received in revised form 17 June 1999 ; accepted 31

20 Apr 2002: A Ternary Metal Binding Site in the C2 Domain of Phosphoinositide-SpecificPhospholipase C-δ1†,‡. Lars-Oliver Essen,,| Olga Perisic, Denise E. Lynch, Matilda Katan, and Roger L. Williams,. Centre for Protein Engineering, MRC Centre, Hills Road,

20 Apr 2002: Mapping the Phospholipid-binding Surface and TranslocationDeterminants of the C2 Domain from Cytosolic Phospholipase A2. (Received for publication, November 9, 1998, and in revised form, January 14, 1999). Olga Perisic‡, Hugh F. Paterson, Georgina

20 Apr 2002: Catalytic Domain of Phosphoinositide-specificPhospholipase C (PLC)MUTATIONAL ANALYSIS OF RESIDUES WITHIN THE ACTIVE SITE AND HYDROPHOBIC RIDGE OF PLCd1. (Received for publication, November 20, 1997, and in revised form, February 18, 1998). Moira V.

20 Apr 2002: Molecular Cell, Vol. 8, 829–839, October, 2001, Copyright 2001 by Cell Press. The Crystal Structure of the PX Domain from p40phoxBound to Phosphatidylinositol 3-Phosphate. Vam7 (Cheever et al., 2001), SNX3 (Xu et al., 2001b),and p40 phox

20 Apr 2002: Molecular Cell, Vol. 6, 909–919, October, 2000, Copyright 2000 by Cell Press. Structural Determinants of Phosphoinositide3-Kinase Inhibition by Wortmannin, LY294002,Quercetin, Myricetin, and Staurosporine. for proteins such as protein kinase B

20 Apr 2002: Phosphoinositide-Specific Phospholipase Cδ1 Activity toward Micellar Substrates,Inositol 1,2-Cyclic Phosphate, and Other Water-Soluble Substrates: A Sequential. Mechanism and Allosteric Activation†. Yiqin Wu,‡ Olga Perisic, Roger L. Williams,

20 Apr 2002: Structural Mapping of the Catalytic Mechanism for a MammalianPhosphoinositide-Specific Phospholipase C†,‡. Lars-Oliver Essen,,| Olga Perisic, Matilda Katan, Yiqin Wu, Mary F. Roberts, and Roger L. Williams,. Centre for Protein Engineering, MRC

20 Apr 2002: Tyrosine Residues in Phospholipase C2 Essential for the EnzymeFunction in B-cell Signaling. Received for publication, August 8, 2001, and in revised form, October 9, 2001Published, JBC Papers in Press, October 17, 2001, DOI 10.1074/jbc.M107577200.

12 Oct 2002: Dimitrios Karathanassis1,Robert V.Stahelin2, Jero nimo Bravo1,3,Olga Perisic1, Christine M.Pacold1,Wonhwa Cho2 and Roger L.Williams1,4. 1MRC Laboratory of Molecular Biology, Hills Road,Cambridge CB2 2QH, UK and 2Department of Chemistry,University

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

26 Nov 2002: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2002. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 97,585 Agricultural. 1,035,782Rates. 6,124 Urban not on building leases. 15,677,702Agency,

2 Dec 2002: For more information about thecompany please go towww.nymt.org.uk. If you are interestedvolunteering for the NYMT in a vacation,at our offices in Shaftesbury Avenue,London please download an

5 Sep 2003: Molecular Cell, Vol. 12, 39–50, July, 2003, Copyright 2003 by Cell Press. PB1 Domain-Mediated Heterodimerizationin NADPH Oxidase and Signaling Complexesof Atypical Protein Kinase C with Par6 and p62. al, 2003). The molecular organization of

27 Oct 2003: Molecular Cell, Vol. 12, 863–874, October, 2003, Copyright 2003 by Cell Press. Structural Basis for Arl1-Dependent Targeting ofHomodimeric GRIP Domains to the Golgi Apparatus. elle (Donaldson and Jackson, 2000). For example, Arf1recruits COP I

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,

28 Nov 2003: T R I N I T Y C O L L E G E. ACCOUNTS FOR THE YEAR ENDED 30 JUNE 2003. 2. £ £ £College Estates: College Estates:. Miscellaneous rents, rent charges, etc. 2,309 Agricultural. 991,870Rates. 46,612 Urban not on building leases. 16,591,811Agency,