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Ortho-quinone prodrug strategy (self-immolative linkers)
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=231878 May 2024: Ortho-quinone prodrug strategy (self-immolativelinkers). BACKGROUND. The para-quinones doxorubicin (Adriamycin),geldanamycin, mitoxantrone and mitomycin C have lowerredox-cycling rates than ortho-quinones and aresuccessfully used in the clinic. -
MutREAD – Mutational Signature Detection by Restriction…
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=232238 May 2024: MutREAD – Mutational Signature Detection byRestriction Enzyme-Associated DNA Sequencing. BACKGROUND. The successful application of mutational signatures in clinical settingsrequires availability of a cost-effective, scalable detection method that -
LGR5 monoclonal antibody for cancer immunotherapy
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=235728 May 2024: LGR5 monoclonal antibody for cancerimmunotherapy. BACKGROUND. In 2020, there were 1.9 million new cases of colorectal cancer, which is the 3rdmost common cancer worldwide. Liver cancer and Leukaemia are the 6th and 13th. most common cancer types, -
Mouse Models of Essential Thrombocythemia (ET) and Myelofibrosis (MF) …
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=238888 May 2024: Mouse Models of Essential Thrombocythemia(ET) and Myelofibrosis (MF) – Available forPreclinical Studies? Background. Researchers at the University of Cambridge have generated fully characterised,conditional knock-in mouse models for essential -
PredictImmune
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=246048 May 2024: PredictImmune. PredictImmune. HELPING PATIENTS DIAGNOSED WITHCHRONIC IMMUNE-MEDIATED DISORDERS TOLIVE NORMAL AND HEALTHY LIVES. Website. Overview. PredictImmune developes prognostic assays that predict disease progression forpatients with -
Matta
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=250158 May 2024: Matta. Matta. BUILDING AI TO MANUFACTURE THEIMPOSSIBLE. Website. Overview. At Matta we are building the AI operating system for additive manufacturing. Ourtechnology is based on state-of-the-art research by engineers and scientists atCambridge. We -
Biophonics
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=250188 May 2024: Biophonics. Biophonics. ENABLING WIDESPREAD EARLY DETECTIONOF VALVULAR HEART DISEASE WITH AUNIQUE MEDICAL DEVICE. Website. Overview. Nearly 2 million people in the UK suffer from significant valvular heart disease, yetmore than half remain -
OutSee
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=250248 May 2024: OutSee. OutSee. DISCOVERING NOVEL DRUG TARGETS USINGAN INNOVATIVE AI GENOMICS TECHNOLOGYTHAT UNCOVERS DISEASE-MODULATINGBIOLOGICAL MECHANISMS. Website. Overview. OutSee is being launched to take advantage of the opportunity to exploit large-scale -
Sparxell
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=250278 May 2024: Sparxell. Sparxell. THE NEXT GENERATION OF COLOURS ANDEFFECTS. Website. The Challenge. Glitters can take many sizes and shapes (from the sequins used in fashion to thefine powder used in the paint of 1 in 4 cars sold in Europe or found in -
Bamboo cricket bat
https://www.enterprise.cam.ac.uk/content-to-pdf/?postid=262368 May 2024: Bamboo cricket bat. BACKGROUND. This innovative bat combines its high-performance properties with the sustainablecredentials which derive from fast growing and widespread bamboo. DEVELOPED BY RESEARCHERS FROM CAMBRIDGE'S CENTRE FOR NATURAL MATERIAL
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