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17 May 2024: Many different manipulations have been examined, with varied outcomes depending on the intensity, timing and duration of the insult. ... Together these data suggest a complex response of the placenta to reduced oxygen availability, which links to changes

17 May 2024: Director of Germline and Epigenomics Research. Member of the Physiology, Development and Neuroscience Department.

16 May 2024: Search site. Centre for Trophoblast Research. Congratulations to Dr Sferruzzi-Perri who has been awarded a New Investigator Research Grant from the MRC for work on biomarkers of materno-fetal health ... of materno-fetal health and the role of placental

17 May 2024: Wiley on Wed, 01/06/2022 - 18:54. Staff news:. The CTR community are delighted to announce these staff achievements:. ... Irving, formerly a CTR Next Generation Fellow, is a Group Leader & MRC Career Development Fellow in the Department of Obstetrics &

16 May 2024: Programme. 2:00pm – 3:15 pm - Flash talks. The obstetric dilemma – Dr Emma Pomeroy. ... of Physiology). 4:45pm Talk. Policy Making and CSaP’s links to the SRI in reproduction.

17 May 2024: Search site. Centre for Trophoblast Research. Dr Irving Aye. • Metabolic regulation of epigenetics during trophoblast differentiation and its impact on early placental development. • Impact of fetal sex on placental function in normal and

16 May 2024: Search site. Centre for Trophoblast Research. CTR visitor Katrien De Clercq awarded the highly competitive Elsevier Placenta New Investigator Award at IFPA. ... Many congratulations! Submitted by Administrator on Fri, 04/10/2019 - 14:24. CTR visitor

17 May 2024: Most content will be pre-recorded lectures and practical sessions given by investigators at the forefront of the placental biology field. ... There will be daily, live and interactive sessions with the speakers on Zoom, and opportunities to give flash

16 May 2024: This was an exciting result for us,” said Myriam Hemberger, a group leader at the Babraham Institute. ... Main image description:. The egg’s epigenetic ‘blueprint’ is important for placenta development in pregnancy.

17 May 2024: Giussani, MA, PhD, ScD, who has been awarded a Fellowship ad eundem from The Royal College of Obstetrics & Gynaecology (RCOG). ... Professor Dino A. Giussani, MA, PhD, ScD was recently awarded a Fellowship ad eundem from The Royal College of Obstetrics &

17 May 2024: The researchers used Vitamin C because it is a well-established and used anti-oxidant. ... Chronic fetal hypoxia impairs oxygen delivery at critical periods of development of the baby’s central nervous system.

17 May 2024: Search site. Centre for Trophoblast Research. watson_png.png. 2024 University of Cambridge.

16 May 2024: Search site. Centre for Trophoblast Research. The CD94/NKG2A inhibitory receptor educates uterine NK cells to optimize pregnancy outcomes in humans and mice. ... The conserved CD94/NKG2A inhibitory receptor is expressed by nearly all human and 50% of

16 May 2024: Search site. Centre for Trophoblast Research. Double-label immunohistochemistry to assess labyrinth structure of the mouse placenta with stereology. ... parameters in the labyrinth zone such as maternal blood spaces,fetal capillaries, surface area for

16 May 2024: We then study the recovery process: 1) within the target tissue [2,3]; 2) between adjacent tissues; 3) between organs within the body. ... We will study how this bidirectional communication happens, and what kind of signalling ‘computation’ takes

16 May 2024: The board then decided to award her with the 2020 Hans Sigrist Prize.”. ... An interview with Dr. Sferruzzi-Perri will also soon be published on the website.

16 May 2024: Providing bioinformatics support and teaching for the groups within the CTR. ... Russell Hamilton. Before joining the CTR I worked at Cambridge Epigenetix (CEGX) as a bioinformatician working on the development of epigenetics tools to enable single base

17 May 2024: Search site. Centre for Trophoblast Research. Dr Naomi McGovern. Dr Naomi McGovern. Sir Henry Dale Fellow, Department of Pathology. 2024 University of Cambridge.

16 May 2024: A special supplement of the American Journal of Obstetrics and Gynecology dedicated to the placenta has just been published..

16 May 2024: Search site. Centre for Trophoblast Research. Owen Vaughan. Research summary. I continue my research at the University of Cambridge. ... These observations are related to changes in epigenetic marks, gene and protein expression, and structure in fetal

16 May 2024: Search site. Centre for Trophoblast Research. Publications. Publications. 2024 University of Cambridge.

17 May 2024: Abstract: Aneuploidy, the presence of an abnormal number of chromosomes, is a major cause of early pregnancy loss in humans. ... Our results present the first detailed analysis of post-implantation development of aneuploid human embryos.

17 May 2024: Search site. Centre for Trophoblast Research. Sung Sam Gong. Currently Dr Gong is working as a Senior Research Associate in Bioinformatics at the Obstetrics & Gynaecology Department on a project funded by ... The overarching aim is to identify biomarkers

17 May 2024: Graduate Student, CTR-Sir Robert Edwards Churchill College PhD studentship 2023. Supervisors: Kathy Niakan, Thorsten Boroviak.

17 May 2024: Search site. Centre for Trophoblast Research. Dr Jennifer Nichols. Principal Investigator, Stem Cell Institute, Gleeson Building. Contact Details. Affiliations. Classifications:. 2024 University of Cambridge.

17 May 2024: Search site. Centre for Trophoblast Research. kathy-cropped.jpg. Alt Text:. 2023 Annual Meeting. Title Text:. 2023 Annual Meeting. 2024 University of Cambridge.

17 May 2024: Search site. Centre for Trophoblast Research. burton_png.png. 2024 University of Cambridge.

16 May 2024: She takes over the role from Professor Chris Abell, who died suddenly in October. ... She has the skills and the experience that such a wide-ranging portfolio call for.

17 May 2024: Together with the groups of Prof. Guillaume Charras from University College London, Prof. ... Timo Betz from the University of Münster, were placed on soft and stiff substrates.

16 May 2024: III and V of the lightest males were decreased compared to their heaviest counterparts. ... Thus, in normal mouse pregnancy, placental structure, function and mitochondrial phenotype are differentially responsive to growth of the female and the male fetus

16 May 2024: non-coding RNAs to the identity and developmental potential of the trophoblast stem cell compartment. ... and Hemberger M. (2020). TET1 and 5-hydroxymethylation preserve the stem cell state of mouse trophoblast.

16 May 2024: Search site. Centre for Trophoblast Research. how_should_i_store_my_data_2022-11-17.pdf. 2024 University of Cambridge.

17 May 2024: Changes include a switch from histotrophic to hemotrophic nutrition, and a threefold rise in the intraplacental oxygen concentration. ... Transcripts higher in the first trimester were associated with synthesis and ER processing of peptide hormones, and

16 May 2024: OUTCOMES. Deep trophoblast invasion into the maternal decidua is a particular feature of human pregnancy. ... This means that the ‘trophoblast’ cell lines currently in use should rapidly become obsolete.

17 May 2024: Support our research. Please visit our menu for more information about how you can support research at the Centre for Trophoblast Research through embryo donation or by making a financial contribution.

16 May 2024: As trophoblasts migrate into the uterus, they encounter distinct maternal microenvironments and metabolic cues that guide their differentiation and function. ... tools. These findings will enable the reconstruction of metabolic-driven mechanisms

16 May 2024: Search site. Centre for Trophoblast Research. The RNA landscape of the human placenta in health and disease. ... We identify multiple circular RNAs and validate 6 of these by Sanger sequencing across the back-splice junction.

16 May 2024: reside. Hofbauer cells (HBC) are fetal-derived macrophages found within the placental villous tree. ... However, their exact characteristics and functions are quite obscure despite being the only placental immune cell.

16 May 2024: The role for bivalent chromatin in placenta remains contentious (Rugg-Gunn et al. ... The programming of epigenetic modifications is essential for gene regulation and lineage specification during development.

17 May 2024: Search site. Centre for Trophoblast Research. CTR Annual Meeting 2022. the Cambridge Academy of Therapeutic Sciences (CATS) and the Centre for Trophoblast Research (CTR) held a workshop on 18–19 July ... 2022, focused on the question: how can we

16 May 2024: Search site. Centre for Trophoblast Research. Giulia Avellino. Giulia Avellino. Graduate Student, CTR PhD Studentship 2020.

17 May 2024: There are also opportunities to participate and present in interdisciplinary seminars hosted by Cambridge Reproduction Strategic Research Initiative of which the CTR is a founding member. ... Students will gain training in our Placental Biology Course

17 May 2024: Understanding the molecular mechanisms that control human yolk sac progenitor (hypoblast) cell development. ... Project description. We seek to understand the molecular mechanisms that regulate early human development.

16 May 2024: CTR Annual Meeting 2021. Placental-endometrial dialogue and pregnancy. Celebrating the achievements of CTR Director. ... We are really excited to announce the programme for the upcoming CTR annual meeting.

16 May 2024: His group aims to elucidate the functional roles that TEs play in the contexts of development, health and disease. ... Key publications:. Publications whilst at the CTR. Booth MJ, Ost TWB, Beraldi D, Bell NM, Branco MR, Reik W, Balasubramanian S (2013)

16 May 2024: Search site. Centre for Trophoblast Research. Natasha Cavell. Natasha Cavell. Graduate Student, Newnham College - CTR PhD Studentship 2023.

17 May 2024: Search site. Centre for Trophoblast Research. Nisha Padmanabhan. Nisha is currently a Research Fellow at the Duke-NUS Medical School in Singapore in Professor Patrick Tan's laboratory.She can be ... Former CTR Graduate Student. Affiliations.

16 May 2024: In view of these changes, the early placenta has been described as ‘hypoxic’. ... The transition is associated with a three-fold rise in the intraplacental O.

17 May 2024: Stain; H & E. Fig. 112 in 'The Human Placenta'. View – Download. ... Stain; H & E. Fig. 132 in 'The Human Placenta'. View – Download.

17 May 2024: th. November 2023. When a reference is submitted, both the referee and the applicant will receive a confirmation at the emails listed below. ... Referee email. Referee phone number. Please include a country code for a phone number in the form 00 1234