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17 May 2024: Many different manipulations have been examined, with varied outcomes depending on the intensity, timing and duration of the insult. ... Together these data suggest a complex response of the placenta to reduced oxygen availability, which links to changes

17 May 2024: Stain; H & E. Fig. 112 in 'The Human Placenta'. View – Download. ... Stain; H & E. Fig. 132 in 'The Human Placenta'. View – Download.

16 May 2024: My work involves using genetic models of the System A transporter genes to examine the following:. ... Study the role of system A activity in fetal tissues. Establish cell signalling pathways involved in system A activity.

17 May 2024: Search site. Centre for Trophoblast Research. naomi_png.png. 2024 University of Cambridge.

17 May 2024: This was an exciting result for us,” said Myriam Hemberger, a group leader at the Babraham Institute. ... Main image description:. The egg’s epigenetic ‘blueprint’ is important for placenta development in pregnancy.

16 May 2024: Search site. Centre for Trophoblast Research. Professor Anne Ferguson-Smith. Professor Anne Ferguson-Smith. Arthur Balfour Professor of Genetics. Wellcome Trust Senior Investigator. Group Leader: Ferguson-Smith Group. Pro-Vice-Chancellor for Research

16 May 2024: Search site. Centre for Trophoblast Research. Review on oxygen and development of the human placenta just published in Reproduction. ... has just been published in Reproduction. You can read the full article here.

16 May 2024: Fetal hypoxia can be diagnosed when a scan during pregnancy shows the baby is not growing properly. ... This is the first time that MitoQ has been tested during sheep pregnancy.

17 May 2024: Graham was Director of the CTR for the last 14 years, leading the focus of excellence to promote scientific study of the placenta and maternal-fetal interactions during pregnancy. ... Kathy Niakan. Kathy was one of the first Next Generation Fellows in

17 May 2024: The placenta also stores glucose in the form of glycogen, the function of which remains unknown. ... that emerge and to better understand the relationship between placental glycogen and fetal growth.

16 May 2024: CTR SAB Member 2016-2023. Co-Director T32 Training Program in Perinatal Medicine and Biology.

17 May 2024: Submitted by Noelia Corral Ferre on Mon, 30/11/2020 - 16:11. We’re used to the idea that as adults we have some control over our destiny: what we eat ... But the risks of heart disease and diabetes can be programmed much earlier – even before we are

17 May 2024: Search site. Centre for Trophoblast Research. Dr Amanda Sferruzzi-Perri awarded the Andrée Gruslin Award from IFPA: the Andrée Gruslin Award is named in honour of Dr. ... Amanda will receive the award at the IFPA meeting in Manchester later this year.

16 May 2024: Search site. Centre for Trophoblast Research. CTR member Francesca Gaccioli's Pregnancy Outcome Prediction (POP) paper has been published in Placenta. ... In this paper, we outline some of the challenges and opportunities in this area.

16 May 2024: Search site. Centre for Trophoblast Research. CTR member Margherita Turco awarded ERC starting grant. ... Submitted by Administrator on Fri, 06/09/2019 - 13:19. Many congratulations to CTR member Margherita Turco who was recently awarded an ERC starting

17 May 2024: Search site. Centre for Trophoblast Research. Tamsin Smyth. Tamsin Smyth. Events and Communications Administrator. 2024 University of Cambridge.

17 May 2024: A subset of the SGA cases displayed signs of FGR. Cases of preterm delivery were also included. ... In conclusion, FGR and pre‐eclampsia are associated with T‐cell infiltration of the placenta and placental pathological abnormalities.

16 May 2024: The effects of B. breve UCC2003 on feto-placental growth are mediated, in part, by changes in the maternal and placental metabolome (i.e. ... This study provides knowledge towards a novel and safe therapeutic strategy for treating pregnancy disorders via

17 May 2024: Search site. Centre for Trophoblast Research. burton_png.png. 2024 University of Cambridge.

16 May 2024: Search site. Centre for Trophoblast Research. Major scientific milestones. Listed in these pages are contributions from the CTR that have had a major impact on our understanding of trophoblast and placental ... biology. A full list of papers published by

16 May 2024: Search site. Centre for Trophoblast Research. Non-canonical mitochondrial unfolded protein response impairs placental oxidative phosphorylation in early-onset pre-eclampsia": new article published by CTR team in PNAS. ... Submitted by Administrator on Fri

17 May 2024: Hemberger . Abstract. Normal function of the placenta depends on the earliest developmental stages when trophoblast cells differentiate and invade into the endometrium to establish the definitive maternal-fetal interface. ... Previously, we identified

17 May 2024: Search site. Centre for Trophoblast Research. Deletion of the Imprinted Phlda2 Gene Increases Placental Passive Permeability in the Mouse. ... Using stereology, we show that the morphology of the labyrinthine zone in Phlda2. /.

16 May 2024: Search site. Centre for Trophoblast Research. Congratulations to CTR Next Generation Research Fellow Dr Simon Tunster who secured an Early Career Grant from the Society for Endocrinology! ... Simon is a CTR Next Generation Research Fellow and his current

16 May 2024: There will also be opportunities and support to learn other molecular biology techniques necessary to further refine the hypotheses generated. ... Glucose and oxygen in the early intrauterine environment and their role in developmental abnormalities.

16 May 2024: Search site. Centre for Trophoblast Research. Dr Kathy Niakan announced as next Director of the CTR. ... Reproduction. We look forward most warmly to her rejoining the CTR, and contributing to our research strengths in trophoblast and placental biology.

16 May 2024: Search site. Centre for Trophoblast Research. Professor Myriam Hemberger receives march of Dimes prize. Submitted by Administrator on Fri, 10/05/2019 - 11:58. Congratulations to Myriam Hemberger for her march of Dimes prize. Full details here:. 2024

16 May 2024: Search site. Centre for Trophoblast Research. Mapping cells of the reproductive tract across the lifespan will help fill critical gaps in our knowledge about health. ... Roser Vento-Tormo. Roser is mapping the female reproductive system to better

17 May 2024: Submitted by Noelia Corral Ferre on Mon, 30/03/2020 - 10:03. Yassen Abbas, CTR Research Associate, publishes the research article "Generation of a three-dimensional collagen scaffold-based model of ... Click here to read the full research article. 2024

16 May 2024: Currently we are working on:. Placenta infection - we use single-cell transcriptomics to describe the placental primary defence mechanisms against three pathogens that are known to cause fetal and maternal complications ... cells differentiate, invade

16 May 2024: CTR SAB Member 2016-2023. Co-Director T32 Training Program in Perinatal Medicine and Biology. ... CTR SAB Member 2016-2023. Head of the Department of Developmental Pathology.

17 May 2024: A subset of the SGA cases displayed signs of FGR. Cases of preterm delivery were also included. ... In conclusion, FGR and pre‐eclampsia are associated with T‐cell infiltration of the placenta and placental pathological abnormalities.

17 May 2024: Submitted by Administrator on Thu, 21/06/2018 - 11:29. Romina Plitman received the prestigious award for her PhD work funded by the CTR. ... Romina was a CTR funded PhD student until March 2018 when she was awarded her PhD.

16 May 2024: Understanding the molecular mechanisms that control human yolk sac progenitor (hypoblast) cell development. ... Project description. We seek to understand the molecular mechanisms that regulate early human development.

17 May 2024: Search site. Centre for Trophoblast Research. The impact of DNA methylation on gene regulation in placental development. ... DNA methylation is dramatically reprogrammed during early development in both the embryonic and extra-embryonic lineages.

17 May 2024: Search site. Centre for Trophoblast Research. New study explores the links between prenatal sex steroid hormones, maternal health and autism. ... Together, these findings support the theory that autistic traits in the children are associated with

16 May 2024: If your degree is not from the UK, please check International Qualifications to find the equivalent in your country. ... We are looking for strong candidates that will contribute to the science in the CTR and have potential as researchers.

16 May 2024: However, the mechanisms by which these intergenerational responses to stress occur remain largely unknown. ... two cysteine synthase genes, cysl-1 and cysl-2, and the acyltransferase rhy-1.

17 May 2024: However, the molecular mechanisms regulating adiponectin secretion from maternal adipose tissues in pregnancy are poorly understood. ... The role of insulin, inflammation and ER stress in mediating adiponectin ubiquitination and degradation was examined

16 May 2024: A subset of the SGA cases displayed signs of FGR. Cases of preterm delivery were also included. ... In conclusion, FGR and pre‐eclampsia are associated with T‐cell infiltration of the placenta and placental pathological abnormalities.

16 May 2024: Search site. Centre for Trophoblast Research. Illustrating uterine pulsability index, vascular resistance and material arterial blood pressures. 2024 University of Cambridge.

17 May 2024: Search site. Centre for Trophoblast Research. Igf2 deletion alters mouse placenta endocrine capacity in a sexually-dimorphic manner, just published in Journal of Endocrinology. Submitted by Noelia Corral Ferre on Mon, 11/05/2020 - 09:24. Igf2

16 May 2024: sections. The larger Boyd sections have been scanned and images are posted on a separate page (Image Collections). ... at reviewing the theories of Sir Peter Medawar relating to the immunology of maternal-fetal interactions.

17 May 2024: Search site. Centre for Trophoblast Research. ctr_logo-twotone-white.png. 2024 University of Cambridge.

16 May 2024: Objective. To test the hypothesis that slowing of fetal growth or elevated maternal serum levels of markers of placental hypoxia in late gestation will be associated with earlier term labor. ... Data were analyzed using logistic regression and Cox

16 May 2024: recruitment of the apical proteins, whereas the level of RhoA controls lateral mobility of the apical proteins. ... Overall, this work indicates a direct role of zygotic genome activation in regulating the timing of cell polarization.

16 May 2024: Search site. Centre for Trophoblast Research. External weblinks. 2024 University of Cambridge.

17 May 2024: Search site. Centre for Trophoblast Research. Kings Fellow - Professor Ashley Moffett and Dr Francesco Colucci have jointly received and Invesigator Award from the Wellcome Trust. ... Submitted by Administrator on Tue, 13/09/2016 - 13:40. Kings Fellow -

17 May 2024: Search site. Centre for Trophoblast Research. CTR manager in Channel 4 documentary on stillbirth- placental malfunction is often an important factor in such outcomes. ... Submitted by Administrator on Fri, 19/10/2018 - 13:01. CTR manager Professor Gordon

16 May 2024: Search site. Centre for Trophoblast Research. a3de6a45-5086-bd65-e01d-1d5e1d9645d4.png. 2024 University of Cambridge.