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  2. AOC Minutes 230623

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_230623_redacted.pdf
    23 Jan 2024: asked what people’s thoughts were about group training for schedule 1 training, specifically CO2. ... will distribute what we are telling people at the beginning of the courses regarding having cameras on.
  3. Application Form for NACWO Course | University Biomedical Services…

    https://www.ubs.admin.cam.ac.uk/application-form-nacwo-course
    3 May 2023: A confirmatory email will be sent when a place on the course has been reserved.
  4. Organoids: Advances and Applications | University Biomedical Services …

    https://www.ubs.admin.cam.ac.uk/events/organoids-advances-and-applications
    7 Feb 2024: 9–11 September 2024 Wellcome Genome Campus, UK and online Highlighting improved functionality and large-scale approaches Summary Organoids have revolutionised biology and the development of organoid model systems continues to open up opportunities
  5. 2024 | University Biomedical Services (UBS)

    https://www.ubs.admin.cam.ac.uk/home-office-licensing/non-technical-summaries/2024
    30 Apr 2024: Search site. University Biomedical Services (UBS). 2024. Non-Technical Summaries 2024. generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf (175.18 KB).
  6. AOC Minutes 17th March 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_170323_redacted.pdf
    17 Jan 2024: A survey was sent out through the Animal Welfare Management Discussion Group and the Home Office Liaison, Training and Information Forum Group regarding people’s thoughts on how the Home Office ... Feedback was given on the Colony Management Group
  7. Train the Trainer Course (University of Cambridge) | University…

    https://www.ubs.admin.cam.ac.uk/events/train-trainer-course-university-cambridge-0
    17 Apr 2024: Online and in person options are available. This course is suitable for those that are new to training or will soon be training others in practical tasks.
  8. AOC Minutes 21st April 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_210423_redacted.pdf
    17 Jan 2024: A few people are unable to wear powered respirators so will need face fit testing for disposable respirators. ... will train people to use disposable respirators. 9. Training and Competencies Reminder that IAT live sessions will start again next week.
  9. AOC Minutes 23rd February 2024

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_230224_redacted.pdf
    25 Apr 2024: The PAT test is ongoing. 8. Training and Competencies It has been noticed that some people are still performing Schedule 1 that have not completed module 6.3. ... People must complete 6.3 if they don’t have a PIL. NACWOs should check when uploading
  10. AOC Minutes 19th May 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_190523_redacted.pdf
    17 Jan 2024: 11 people are currently waiting for schedule 1 training. have two new NACWO’s added to the PEL,. ... has started chasing people who are not completing the boxes. The reminders have gone to individual researchers and to NACWO’s to remind their
  11. Train the Trainer Course (University of Cambridge) | University…

    https://www.ubs.admin.cam.ac.uk/events/train-trainer-course-university-cambridge-1
    17 Apr 2024: Online and in person options are available. This course is suitable for those that are new to training or will soon be training others in practical tasks.
  12. AOC Minutes 20th January 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_200123_redacted.pdf
    17 Jan 2024: The diet that has been given to adults has. Training Centre is there to support people with any training needs or questions.
  13. NACWO Refresher Course | University Biomedical Services (UBS)

    https://www.ubs.admin.cam.ac.uk/training-centre/nacwo-refresher-course
    14 Jun 2023: This course is self-paced, with a three month completion deadline. It carries 24 IAT CPD points and the cost is £205.80 for internal candidates and £210 for external candidates. The estimated time for completion – including the assessments –
  14. Nominated Assessor Course (University of Cambridge) | University…

    https://www.ubs.admin.cam.ac.uk/events/nominated-assessor-course-university-cambridge-0
    17 Apr 2024: Nominated Assessor Course Online and in person options are available. This course is suitable for those that will be assessing others and introduces the Direct Observation of Practical Skills (DOPS) system.
  15. Nominated Assessor Course (University of Cambridge) | University…

    https://www.ubs.admin.cam.ac.uk/events/nominated-assessor-course-university-cambridge-1
    17 Apr 2024: Nominated Assessor Course Online and in person options are available. This course is suitable for those that will be assessing others and introduces the Direct Observation of Practical Skills (DOPS) system.
  16. 2023 | University Biomedical Services (UBS)

    https://www.ubs.admin.cam.ac.uk/home-office-licensing/non-technical-summaries/2023
    30 Apr 2024: Search site. University Biomedical Services (UBS). 2023. Non-Technical Summaries 2023. axon_degeneration_and_repair_non-technical_summary_redacted.pdf (140.91 KB).
  17. AOC Minutes 17th February 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/aoc_minutes_170223_redacted.pdf
    17 Jan 2024: A reminder to keep an eye on AssessNET to sign off accidents and incidents if you manage people.
  18. AWERB Standing Committee Meeting Minutes 25th October 2023

    https://www.ubs.admin.cam.ac.uk/system/files/public/awerb_standing_minutes_251023_redacted.pdf
    28 Nov 2023: people within the group are able to make decisions if the Licence Holder is not available.
  19. Axon degeneration and repair (non-technical summary)

    https://www.ubs.admin.cam.ac.uk/system/files/public/axon_degeneration_and_repair_non-technical_summary_redacted.pdf
    30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... Individual people in families known to be at risk will also be able to determine their
  20. Exploring Bioelectronic Approaches to Nervous System Restoration in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/exploring_bioelectronic_approaches_to_nervous_system_restoration_in_large_animals_non-technical_sum_redacted.pdf
    30 Apr 2024: We're working on a project that studies diseases that affect the entire nervous system, just like they would in people. ... This will help us get reliable data that can be used to develop and improve treatments for nerve diseases in people.
  21. AWERB Non-Regulated Procedure Committee Redacted Minutes | University …

    https://www.ubs.admin.cam.ac.uk/animal-welfare-ethical-review-body/awerb-redacted-minutes/awerb-non-regulated-procedure-committee
    16 Apr 2024: Search site. University Biomedical Services (UBS). AWERB Non-Regulated Procedure Committee Redacted Minutes. 2024 AWERB Non-Regulated Procedure Committee Redacted Minutes. awerb_non-reg_committee_minutes_040124_redacted.pdf (59.83 KB).
  22. Understanding Infection Pathogenesis to Guide Therapies…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_infection_pathogenesis_to_guide_therapies_non-technical_summary_redacted.pdf
    30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly.
  23. Neurobehavioural Mechanisms Underlying Mood, Anxiety and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf
    30 Apr 2024: The World Health Organisation estimates that worldwide, 301 million people live with anxiety, 280 million people live with depression, and 326 million people experience post-traumatic stress disorder. ... benefit people living with mental health
  24. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: It affects about 1 in 400 people in the UK. Crohn's disease affects about 1 in 700 people in the UK. ... In the shorter-term this will involve making new discoveries on the types and behaviour of common gut bacteria found in people and how these interact
  25. Cartilage repair and replacement

    https://www.ubs.admin.cam.ac.uk/system/files/public/cartilage_repair_and_replacement_non-technical_summary_redacted.pdf
    29 Apr 2024: As a result, while it is not possible at this stage to provide a meaningful estimate of the total number of people this technology would benefit it is clear that the
  26. Interaction between the immune system and tumours (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf
    30 Apr 2024: Why is it important to undertake this work? It is now predicted that 1 in 2 people will develop cancer in their lifetime and despite advances with new treatments they do ... We subscribe to the NC3Rs email updates and also receive regular updates from
  27. Proteotoxicity in development and ageing (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/proteotoxicity_in_development_and_ageing_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:21pm, 25 Apr 2024 Page 3 of 10. Dementias are the biggest health challenge of our generation; one in three people born today will develop the disease. ... With one million people in the UK predicted to have dementia by 2025 and the current
  28. Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf
    30 Apr 2024: benefit people living with mental health disorders through the development of new treatments. ... In the longer term, understanding the risk factors that predict whether individuals are more vulnerable to developing mental health disorders may allow
  29. The development of in vivo expressed biologics as a platform for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf
    30 Apr 2024: Cancer, cardiovascular disease, diabetes and chronic respiratory diseases killed approximately 33.2 million people worldwide in 2019, a 28% increase compared to 2000. ... In the medium term this will allow us to choose the best designs or methods to take
  30. Discovery and development of treatments for immunological diseases

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf
    29 Apr 2024: Why is it important to undertake this work? Despite decades of research, millions of people live with serious immune mediated disease such as colitis, arthritis, systemic lupus erythematosus (SLE) and atopic ... dermatitis. For example rheumatoid
  31. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: Each client is developing drugs which will hopefully contribute to helping people with various diseases with an unmet clinical need. ... For example, we have a large program of work studying haemophilia, a rare (1 in 30,000 people) but life-changing
  32. Implantation of seeded scaffolds for tissue!organ development…

    https://www.ubs.admin.cam.ac.uk/system/files/public/implantation_of_seeded_scaffolds_for_tissueorgan_development_non-technical_summary_redacted.pdf
    30 Apr 2024: There are currently 6,079 people waiting for a transplant in the UK and many more who are not on the waiting list would benefit from having a diseased or damaged
  33. Tissue response following synovial joint injury and potential for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/tissue_response_following_synovial_joint_injury_and_potential_for_therapies_to_restore_joint_structu_redacted.pdf
    30 Apr 2024: The most common form of arthritis, osteoarthritis (OA) is believed to affect an estimated 8 million people in the UK, and worldwide this figure rises to 343 million. ... OA is associated with age but younger people are also affected, often impacting on
  34. Epigenetic inheritence and the control of developmental and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf
    30 Apr 2024: For example, Angelman syndrome, an imprinting disorder leading to severe intellectual disability affects 1 in 12,000-1 in 20,000 people worldwide, and Prader-Willi syndrome, another imprinting disorder linked ... to intellectual disability, compulsive
  35. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: With increased population lifespan, the incidence of people experiencing these devastating disorders will continue to rise. ... Our work has the potential to impact millions of people worldwide both at the social and economic levels.
  36. Mouse developmental genetics to study neurodevelopment and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Currently, there are 1.4 million people that are living with acquired brain injuries and 40,000 deaths only from stroke annually in the UK, and an estimated 69 million people
  37. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: Where possible in our design we blind people to genotype/treatment groups with different people doing infections or analysis. ... We will discuss any advances with the relevant people at our establishment and implement them accordingly.
  38. Investigating the niche of mucosal parasitic nematodes and their…

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf
    30 Apr 2024: Whipworms infect 500 million people worldwide, particularly affecting children 5-15 years of age. ... Hookworms infect 450 million people around the globe, and can cause iron deficiency anaemia, especially in high-risk populations (children and women of
  39. Determining mechanisms of tumour development and relapse following…

    https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf
    29 Apr 2024: Furthermore, to determine whether inhibition of the activities of these proteins will be effective in the treatment of people with cancer. ... Downloaded: 9:12pm, 25 Apr 2024 Page 6 of 11. Some mice can experience weight loss due to the effects of the
  40. Neuronal circuit mechanisms underlying cognitive memory judgements…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neuronal_circuit_mechanisms_underlying_cognitive_memory_judgements_non-technical_summary_redacted.pdf
    30 Apr 2024: In the UK, the number of people with dementia is estimated to exceed one million in 2025 (National Health Service - Dementia guide). ... memory in disorders such as dementia and dyslexia which significant number of people are suffering from.
  41. Provision of an outsourced drug development platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_development_platform_for_the_treatment_of_bleeding_disorders_non-te_redacted.pdf
    30 Apr 2024: Finding treatments for all aspects of patient care therefore is crucial to improve outcomes for people affected. ... All clients that we work with are developing test agents which will hopefully contribute to helping people with various bleeding disorders
  42. Vaccine development and fundamental reseach on viruses of medical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf
    29 Apr 2024: treat people after they have contracted a disease. ... Future pandemics are inevitable as the global population expands - our vaccines aim to reduce the risk of such pandemics happening again, by protecting people through vaccination, against viruses of
  43. Understanding the cell biology behind cardiovascular diseases…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_cell_biology_behind_cardiovascular_diseases_non-technical_summary_redacted.pdf
    30 Apr 2024: However, although many more people now survive, e.g., heart attacks and stroke, the debilitating consequences on quality of life and high risk of a secondary event leads to a huge
  44. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf
    30 Apr 2024: They can cause significant burden to the patient, their families, and society as a whole; 14% of the social care budget in England is spent on people living with neurological conditions, ... Conditions involving neurodegeneration (when brain cells are
  45. Platelets as a therapeutic tool

    https://www.ubs.admin.cam.ac.uk/system/files/public/platelets_as_a_therapeutic_tool_non-technical_summary_redacted.pdf
    30 Apr 2024: It also allows several people to work in parallel in different tissues such as bone marrow and blood that need to be handled fresh, thereby maximising the data obtained from single
  46. Environmental and placental contributions to pregnancy and life-long…

    https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf
    29 Apr 2024: This will be useful in identifying people at risk of ill health from poor conditions during pregnancy and early life. ... For example, our results will help people who work in health care to provide more specialised lifestyle advice and improve pregnancy
  47. Provision of an outsourced drug discovery platform for metabolic and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_metabolic_and_cardiovascular_diseases_non-te_redacted.pdf
    30 Apr 2024: The clients that we work with are developing test agents (potential new drugs) which will hopefully contribute to helping people with various metabolic and cardiovascular diseases where current treatments are not ... The average age of people with NASH
  48. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: The Asthma and Lung UK estimates that approximately 12.7 million people in the UK have a history of longstanding respiratory illness including lung cancer and pulmonary fibrosis (scarring of the ... This will allow people to learn about novel aspects of
  49. Ischaemia Reperfusion Injury and Organ Transplantation (non-technical …

    https://www.ubs.admin.cam.ac.uk/system/files/public/ischaemia_reperfusion_injury_and_organ_transplantation_non-technical_summary_redacted.pdf
    30 Apr 2024: In January 2020, there were 6183 people in the UK currently waiting for an organ transplant.
  50. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: Huntington’s disease is a rare genetic neurodegenerative disorder affecting approximately 2.71 people per 100,000 worldwide.
  51. Concordat on Openness on Animal Research in the UKAnnual ...

    https://www.ubs.admin.cam.ac.uk/sites/www.ubs.admin.cam.ac.uk/files/concordat-on-openness-annual-report-2023.pdf
    15 Nov 2023: Concordat signatories are encouraged to develop policies and processes to support the provision of information to the media, and to ensure that key people in their organisations understand why this is ... Openness means providing information that allows

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