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Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/5/InterPro (1). 0.0. PDRG1. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. At3g15351. p53 and DNA damage-regulated protein 1. None. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/6/InterPro (2). 0.0. Pdrg1. p53 and DNA damage-regulated protein 1. None. ... InterPro (2). 0.0. PDRG1. p53 and DNA damage-regulated protein 1. None. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP03540/7/InterPro (2). 0.0. At3g15351. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/regulation of signal transduction by p53 class mediator. -
Spring Group - Publications
https://www-spring.ch.cam.ac.uk/publications/publications.shtml228. Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction, A. ... 221. Functionalized double strain-promoted stapled peptides for inhibiting p53-MDM2 interaction, K. -
Publications
https://www-neurosciences.medschl.cam.ac.uk/horvathlab/publications/23 Feb 2024: RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels. -
Dr Florian Merkle | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/merkle23 Feb 2024: For example, we recently showed that hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation -
Robert Lamplough Mann, Lieutenant, 7th Dragoon Guards | Jesus College …
https://www.jesus.cam.ac.uk/robert-lamplough-mann-lieutenant-7th-dragoon-guards26 Jul 2024: Mann was originally thought to have been wounded on 29 December 1914 and was recorded as a prisoner of war on 25 March 1915 (Jesus College Society Annual Report, 1916, p53).
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Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31
https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/9You are logged on as '':username. password. -
Emeritus - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/group-leaders/emeritus/21 Jul 2023: Tumour suppressor p53 structure and drug discovery. LMB Division - Protein and Nucleic Acid Chemistry.
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Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/0/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31
https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/10You are logged on as '':username. password. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3320
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/3320n. Professor Sir Alan Fersht, FRS, from the PNAC Division of LMB, has been awarded an Advanced ERC Grant of u20ac1.5m for his project u201cTumour suppressor p53: structure, stability and ... 70% of human cancers have p53 directly inactivated by mutation. -
Dr Maria Christophorou | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/christophorou23 Feb 2024: She did her PhD with Gerard Evan at UCSF, where she was able to dissect the relative contributions of different p53 activating signals towards tumour suppression using mouse models of conditional ... p53 perturbation. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/0/InterPro (2). 0.0. P53 apoptosis effector related to PMP22. None. GO (3). ... EMBL (3). InterPro (1). 0.0. PERP. P53 apoptosis effector related to PMP22. -
Member: Florian Merkle - Cambridge Neuroscience
https://neuroscience.cam.ac.uk/member/florianmerkle/My later work in human pluripotent stem cell (hPSC) genomics provided open-access resources for rational cell line selection, revealed recurrent mutations in p53 that profoundly impacted the fields of stem ... Human pluripotent stem cells recurrently -
Protein and Nucleic Acid Chemistry - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/research/protein-and-nucleic-acid-chemistry/20 May 2024: Alan Fersht - Tumour suppressor p53 structure and drug discovery.
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Florian T. Merkle - Institute of Metabolic Science-Metabolic Research …
https://www.mrl.ims.cam.ac.uk/research/principal-investigators/florian-t-merkle/23 Feb 2024: For example, hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation from transplanted cells (Merkle ... Human pluripotent stem cells -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/1/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/3/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/4/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/5/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/6/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09493/7/2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09300/0/InterPro (2). 1.8. hapstr1. HUWE1-associated protein modifying stress responses (Telomere. attrition and p53 response 1 protein). ... Telomere attrition and p53 response 1 protein). None. GO (7). EMBL (2). -
Dr Suzanne Dawn Turner | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/sdturner23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Merkel, O., Morrigl, R.,Turner, S.D. and Kenner, L. (2017) When the -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09958/InterPro (5). 0.5. ZMAT3. Zinc finger matrin-type protein 3 (Zinc. finger protein WIG-1) (p53-activated gene 608 protein). ... protein) (Zinc finger protein WIG-1) (p53-activated gene 608 protein). None. GO (13). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/0/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP01517/negative regulation of DNA damage response, signal transduction by p53 class mediator. -
Professor Alan Warren | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/warren23 Feb 2024: consequence of p53 stabilization in response to ribosomal stress. -
https://www.med.cam.ac.uk/rana/wp-json/wp/v2/pages/26
https://www.med.cam.ac.uk/rana/wp-json/wp/v2/pages/2623 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-01-12T14:44:42","modified_gmt":"2015-01-12T14:44:42","slug":"publications","status" -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/1/None. GO (21). InterPro (2). 2.9. fk24g11. P53 apoptosis effector related to. ... PMP-22 (P53 apoptosis effector-related to pmp22). None. GO (6). EMBL (1). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/3/InterPro (1). 0.0. P53 apoptosis effector related to PMP22. None. GO (6). ... GO (12). InterPro (2). 0.0. PERP. P53 apoptosis effector related to PMP22. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/4/EMBL (2). InterPro (2). 0.0. P53 apoptosis effector related to PMP-22. ... InterPro (2). 0.0. P53 apoptosis effector related to PMP22. None. GO (3). -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/5/GO (3). InterPro (2). 0.0. P53 apoptosis effector related to PMP-22. ... GO (4). InterPro (1). 0.0. PERP. P53 apoptosis effector related to PMP22. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/6/1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). ... EMBL (12). InterPro (2). 0.0. PERP. P53 apoptosis effector related to PMP22. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP07752/7/0.0. P53 apoptosis effector related to PMP22. None. GO (3). EMBL (2). ... InterPro (1). 0.0. P53 apoptosis effector related to PMP22. None. GO (6). -
Publications - Professor Marciniak's Group
https://www.med.cam.ac.uk/marciniak/publications/23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress. -
CDD-MRC Conference on “Genes vs Environment in Cancer” | MRC…
https://www.mrc-tox.cam.ac.uk/news/cdd-mrc-conference-genes-vs-environment-cancer26 Jul 2024: p53 in the response to environmental stressors. -
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/11070
https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/posts/11070can bind to and deactivate an enzyme that controls the stability of the p53 tumour suppressor protein. ... This deactivation allows p53 to be turned on, putting the brakes on cancer growth. -
Greta Skrupskelyte | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/directory/great-skrupskelyte23 Feb 2024: 2018) Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/1/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/3/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/4/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/5/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/6/regulation of signal transduction by p53 class mediator. -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP04148/7/regulation of signal transduction by p53 class mediator. -
https://www.phar.cam.ac.uk/taxonomy/term/5/feed
https://www.phar.cam.ac.uk/taxonomy/term/5/feed26 Jul 2024: Department of Pharmacology - Academic Staff https://www.phar.cam.ac.uk/directory/academicstaff An A-Z directory of all Department members can be found here. The Department provides contact details for all members of the Department. Please follow the -
Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/directory/brian-huntly23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead -
Unknome v3
https://unknome.mrc-lmb.cam.ac.uk/cluster_details/UKP09300/1/2.4. HAPSTR1. HUWE1-associated protein modifying stress responses 1. (Telomere attrition and p53 response 1 protein). ... InterPro (2). 0.0. hapstr1. HUWE1-associated protein modifying stress responses (Telomere. attrition and p53 response 1 protein).
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