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EMBL (2). InterPro (1). 0.0. TP53I13. Tumor protein p53 inducible protein 13. ... None. GO (7). 0.5. Tp53i13. Tumor protein p53-inducible protein 13. None.

23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

26 Jul 2024: His work is now focussed on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53 – the so-called “Guardian of the Genome” – in order to design novel

27 Jul 2024: Department of Physiology, Development and Neuroscience - Academics https://www.pdn.cam.ac.uk/directory/faculty en Sumru Bayin https://www.pdn.cam.ac.uk/staff/bayin <div class="field field-name-field-sd-consultancy field-type-list-boolean

27 Jul 2024: Cancer studies. Including cell cycle and cancer, use of mouse models, genome-wide sequencing and genome-wide disease association, leukaemia, p53, cancer therapeutics, recombinant antibody generation, commercial drug design and development,

27 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). ... 0.5. PERPB. P53 apoptosis effector related to PMP22 B. None. GO (3).

23 Feb 2024: Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Cancer Cell, 2006. 10(6): p. 501-14 PMID:17157790. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI The pathological response to DNA damage does not

Record: P53/43/257. Aerial photograph of east coast of Greenland. Record: P53/43/258. ... Record: P53/43/260. Aerial photograph of east coast of Greenland. Record: P53/43/261.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Kaser Group. Publications. Reviews & Editorials. 2024 University of Cambridge.

InterPro (2). 1.8. hapstr1. HUWE1-associated protein modifying stress responses (Telomere. attrition and p53 response 1 protein). ... Telomere attrition and p53 response 1 protein). None. GO (7). EMBL (2).

InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.

0.6. PDRG1. p53 and DNA damage-regulated protein 1. None. GO (7). ... InterPro (1). 0.0. Pdrg1. p53 and DNA damage-regulated protein 1. None.

Record: P53/43/494. Aerial photograph of east coast of Greenland. Record: P53/43/495. ... Record: P53/43/545. Aerial photograph of tent pitched on flat snow field.

{"id":11414,"date":"2018-01-04T09:33:03","date_gmt":"2018-01-04T09:33:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=11414"},"modified":"2020-11-19T16:55:54","modified_gmt":"2020-11-19T16:55:54","slug":"uncovering-alcohol-derived-metabolite

Record: P53/43/135. Aerial photograph of east coast of Greenland. Record: P53/43/136. ... Record: P53/43/138. Aerial photograph of east coast of Greenland. Record: P53/43/139.

InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.

InterPro (1). 0.0. 100306543. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. 100824728. p53 and DNA damage-regulated protein 1. None.

InterPro (1). 0.0. PDRG1. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. At3g15351. p53 and DNA damage-regulated protein 1. None.

InterPro (2). 0.0. Pdrg1. p53 and DNA damage-regulated protein 1. None. ... InterPro (2). 0.0. PDRG1. p53 and DNA damage-regulated protein 1. None.

InterPro (2). 0.0. At3g15351. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None.

regulation of signal transduction by p53 class mediator.

228. Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction, A. ... 221. Functionalized double strain-promoted stapled peptides for inhibiting p53-MDM2 interaction, K.

23 Feb 2024: RNA exosome mutations in pontocerebellar hypoplasia alter ribosome biogenesis and p53 levels.

23 Feb 2024: For example, we recently showed that hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation

26 Jul 2024: Mann was originally thought to have been wounded on 29 December 1914 and was recorded as a prisoner of war on 25 March 1915 (Jesus College Society Annual Report, 1916, p53).

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21 Jul 2023: Tumour suppressor p53 structure and drug discovery. LMB Division - Protein and Nucleic Acid Chemistry.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

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n. Professor Sir Alan Fersht, FRS, from the PNAC Division of LMB, has been awarded an Advanced ERC Grant of u20ac1.5m for his project u201cTumour suppressor p53: structure, stability and ... 70% of human cancers have p53 directly inactivated by mutation.

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23 Feb 2024: She did her PhD with Gerard Evan at UCSF, where she was able to dissect the relative contributions of different p53 activating signals towards tumour suppression using mouse models of conditional ... p53 perturbation.

My later work in human pluripotent stem cell (hPSC) genomics provided open-access resources for rational cell line selection, revealed recurrent mutations in p53 that profoundly impacted the fields of stem ... Human pluripotent stem cells recurrently

InterPro (2). 0.0. P53 apoptosis effector related to PMP22. None. GO (3). ... EMBL (3). InterPro (1). 0.0. PERP. P53 apoptosis effector related to PMP22.

20 May 2024: Alan Fersht - Tumour suppressor p53 structure and drug discovery.

23 Feb 2024: For example, hPSCs recurrently acquire cancer-associated mutations in the tumour suppressor TP53 (p53) that promote growth in culture and would increase the risk of cancer formation from transplanted cells (Merkle ... Human pluripotent stem cells

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

27 Jul 2024: p53 in the response to environmental stressors.

InterPro (2). 1.8. hapstr1. HUWE1-associated protein modifying stress responses (Telomere. attrition and p53 response 1 protein). ... Telomere attrition and p53 response 1 protein). None. GO (7). EMBL (2).

23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Merkel, O., Morrigl, R.,Turner, S.D. and Kenner, L. (2017) When the

27 Jul 2024: Department of Pharmacology - Academic Staff https://www.phar.cam.ac.uk/directory/academicstaff An A-Z directory of all Department members can be found here. The Department provides contact details for all members of the Department. Please follow the

regulation of signal transduction by p53 class mediator.

InterPro (5). 0.5. ZMAT3. Zinc finger matrin-type protein 3 (Zinc. finger protein WIG-1) (p53-activated gene 608 protein). ... protein) (Zinc finger protein WIG-1) (p53-activated gene 608 protein). None. GO (13).