Search

n. Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... We discovered that about 30% of oncogenic mutants of p53 are just temperatures sensitive and can, in theory, be rescued by small molecules.

EMBL (2). InterPro (1). 0.0. TP53I13. Tumor protein p53 inducible protein 13. ... None. GO (7). 0.5. Tp53i13. Tumor protein p53-inducible protein 13. None.

23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

1) (KCP-1) (P53-induced protein PIGPC1) (Transmembrane protein THW). None. GO (18). ... 0.5. PERPB. P53 apoptosis effector related to PMP22 B. None. GO (3).

23 Feb 2024: Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Cancer Cell, 2006. 10(6): p. 501-14 PMID:17157790. Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI The pathological response to DNA damage does not

Record: P53/43/257. Aerial photograph of east coast of Greenland. Record: P53/43/258. ... Record: P53/43/260. Aerial photograph of east coast of Greenland. Record: P53/43/261.

2023). Molecular function: positive regulation of DNA damage response, signal transduction by p53 class mediator.

23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Kaser Group. Publications. Reviews & Editorials. 2024 University of Cambridge.

InterPro (2). 1.8. hapstr1. HUWE1-associated protein modifying stress responses (Telomere. attrition and p53 response 1 protein). ... Telomere attrition and p53 response 1 protein). None. GO (7). EMBL (2).

InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.

0.6. PDRG1. p53 and DNA damage-regulated protein 1. None. GO (7). ... InterPro (1). 0.0. Pdrg1. p53 and DNA damage-regulated protein 1. None.

25 Jul 2024: His work is now focussed on how mutation affects proteins in the cell cycle, particularly the tumour suppressor p53 – the so-called “Guardian of the Genome” – in order to design novel

26 Jul 2024: Department of Physiology, Development and Neuroscience - Academics https://www.pdn.cam.ac.uk/directory/faculty en Sumru Bayin https://www.pdn.cam.ac.uk/staff/bayin <div class="field field-name-field-sd-consultancy field-type-list-boolean

26 Jul 2024: Cancer studies. Including cell cycle and cancer, use of mouse models, genome-wide sequencing and genome-wide disease association, leukaemia, p53, cancer therapeutics, recombinant antibody generation, commercial drug design and development,

Record: P53/43/494. Aerial photograph of east coast of Greenland. Record: P53/43/495. ... Record: P53/43/545. Aerial photograph of tent pitched on flat snow field.

26 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.

{"id":11414,"date":"2018-01-04T09:33:03","date_gmt":"2018-01-04T09:33:03","guid":{"rendered":"http://www2.mrc-lmb.cam.ac.uk/?p=11414"},"modified":"2020-11-19T16:55:54","modified_gmt":"2020-11-19T16:55:54","slug":"uncovering-alcohol-derived-metabolite

Record: P53/43/135. Aerial photograph of east coast of Greenland. Record: P53/43/136. ... Record: P53/43/138. Aerial photograph of east coast of Greenland. Record: P53/43/139.

InterPro (1). 0.0. Os06g0535333. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. Os07g0485600. p53 and DNA damage-regulated protein 1. None.

InterPro (1). 0.0. 100306543. p53 and DNA damage-regulated protein 1. None. ... InterPro (1). 0.0. 100824728. p53 and DNA damage-regulated protein 1. None.