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doi:10.1016/j.cell.2006.01.047
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/16615893.pdf18 Apr 2006: levels, is that overexpression of exogenous Tsg101 se-. questers endogenous Tsg101 binding partners (Vps28. ... Tal, a Tsg101-spe-. cific E3 ubiquitin ligase, regulates receptor endocytosis and retrovirus. -
Biallelic Variants in ASNA1, Encoding a Cytosolic Targeting Factor of …
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/CircGen_2019.pdf1 Dec 2019: Circ Genom Precis Med. 2019;12:e002507. DOI: 10.1161/CIRCGEN.119.002507 September 2019 397. BACKGROUND: Pediatric cardiomyopathies are a clinically and genetically heterogeneous group of heart muscle disorders associated with high morbidity and -
Membrane fusion is the process whereby two separate lipid ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/MartensMcMahon2008.pdf16 May 2008: derived from a retrovirus. Syncytins function in cell–cell fusion during trophoblast formation. Immunoglobulin (Ig)-like Results that match 1 of 2 words
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Molecular Biology of the CellVol. 18, 3681–3691, September 2007 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/48_Rutkowski_DT_MBC_2007.pdf15 Aug 2007: ER stress did not alterthe electrophoretic migration or protease protection ofp58IPK (Figure 3A), suggesting that there is no substantialrelocalization of endogenous p58IPK during ER stress. ... These results demon-strate a specific interaction between ER -
Estere Seinkmane – November 2018 1 5. Metabolism throughout ...
https://www.murrayedwards.cam.ac.uk/sites/default/files/files/Activity%205_%20Metabolism%20throughout%20the%20day.pdf5 Feb 2019: and Scheer, F. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. ... The circadian clock is an endogenous biological mechanism that drives roughly 24h cycles in various physiological -
TTC5 mediates autoregulation of tubulin via mRNA degradation
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2019.pdf19 Nov 2019: Cite as: Z. Lin et al., Science 10.1126/science.aaz4352 (2019). REPORTS. First release: 14 November 2019 www.sciencemag.org (Page numbers not final at time of first release) 1. Alpha and beta tubulins form obligate heterodimers (hereaf-ter -
Estere Seinkmane – November 2018 1 5. Metabolism throughout ...
https://www.murrayedwards.cam.ac.uk/sites/default/files/files/Activity%205_%20Metabolism%20throughout%20the%20day_Solutions.pdf5 Feb 2019: and Scheer, F. Endogenous circadian system and circadian misalignment impact glucose tolerance via separate mechanisms in humans. ... The circadian clock is an endogenous biological mechanism that drives roughly 24h cycles in various physiological -
Acetylation of MEK2 and I{kappa}B kinase (IKK) activation loop…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/YopJ.pdf28 Nov 2006: 1d). Under our experimental conditions, endogenous levelsof MKK3 protein could not be detected by using the anti-MKK3antibody. ... This effect of expressed YopJ on endogenous MEK1/2was seen as early as 6 h after transfection of cells (data notshown). -
cm6307.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/TAXOL.C&B.pdf18 Feb 1999: Such molecules mightmimic an endogenous cellular factor, presumably a lesspotent one, that helps to stabilise microtubules in normalcytoplasm; the natural reagent might be a small molecule orpart of a microtubule-associated -
Interaction of tau protein with the dynactincomplex Enrico…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/EMBOJ2007-Magnani-Fan.pdf15 Oct 2007: A) Endogenous p150 co-immunopre-cipitates with tau in differentiated SH-SY5Y cells. Immunoprecipitation was performed with anti-tau antibody BR133 and immunoblots withp150 antibody. ... transgenic mice (data not shown) has been hampered by a. likely -
A Conserved Archaeal Pathway for TailAnchored Membrane Protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/70_Sherrill_J_Traffic_2011.pdf11 Nov 2011: We also examined whether archaeal TRC40 could func-tionally replace the endogenous mammalian TRC40 atphysiological concentrations. ... absence of endogenous mam-malian TRC40 using a phenyl- and Diethylaminoethyl (DEAE)-Sepharose-depleted RRL (PD-RRL) -
Are there policy alternatives to Ireland’sausterity? Stephen Kinsella …
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Kinsella/SK191113S.pdf19 Nov 2013: I Steady state solution, simulation, policy experiments. I Generally post-Keynesian features, effective demand,endogenous money, markup based pricing, proceduralrationality, etc. -
2013 – 2014 No.38 Wolfson ReviewTHE The Wolfson Review ...
https://www.wolfson.cam.ac.uk/sites/default/files/2018-10/wolfson-review-web-2014.pdf29 Aug 2017: 2013 – 2014 No.38. Wolfson ReviewTHE. The Wolfson Review. 2013 – 2014 N. o.38. Calendar of 50th Anniversary events. The 50th Anniversary events calendar will be updated regularly at www.WolfsonEvents.com. Friday 19 December 2014: ‘Wolfson -
JCB: Article The Rockefeller University Press $30.00J. Cell…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/63_Rane_NS_JCB_2010.pdf16 Feb 2010: 2007). To maximize the severity of any phenotype, PrP+/ mice were used because endogenous PrP was observed in earlier studies to exacerbate CtmPrP-mediated neurodegeneration (Stewart et al., 2005). -
The EMBO Journal Vol.17 No.18 pp.5273–5285, 1998 Crystal structure ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Owen_McMahon1998.pdf9 Sep 1998: We believe this effectis due to sequestration of endogenous dynamin away fromclathrin-coated pits. -
Molecular Biology of the CellVol. 19, 5093–5103, December 2008 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/LynchMBC5093.pdf24 Jan 2009: It remains tobe determined whether endogenous Syt-1 regulates dense-core vesicle fusion pore expansion and if so, whether Syt-1utilizes membrane binding and curvature induction, or in-teractions with SNAREs, ... Syt Effector Interactions Regulate Fusion -
Sensory Neurons Arouse C. elegans Locomotion via Both Glutamate and…
https://www2.mrc-lmb.cam.ac.uk/groups/wschafer/2015-4.pdf30 Jun 2015: Under these conditions, we only observed endogenous acetylcholine EPSCs. To recordGABAergic postsynaptic currents, the holding potential was 0 mV, at which we only observemIPSCs. ... Supporting InformationS1 Fig. Stimulus-evoked EPSCs and endogenous -
The ER membrane protein complex is a transmembrane domain insertase
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017c.pdf27 Jan 2018: This system contains endogenous mRNAs (primarily encoding the 14 kD globins and a prominent 70 kD protein) that contribute to background, but has the advantage of retaining native cytosolic conditions, most ... aureus is used to digest endogenous mRNA. -
Molecular Biology of the CellVol. 21, 3054 –3069, September ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/RVS161_MBC2010.pdf21 Feb 2011: Previous characterization ofBAR domain proteins has generally involved overproduc-tion, raising the need for in vivo studies characterizing theconsequences of BAR domain mutations in genes expressedat their endogenous level. ... these alterations affect -
«AltRefNo»
https://archives.chu.cam.ac.uk/wp-content/uploads/sites/2/2021/12/MSTN-catalogue.pdf15 Mar 2017: C. Milstein NCUACS 146/3/06. Catalogue of the papers and correspondence of. César Milstein, CH, FRS (1927-2002). By Heather Bird and Timothy E. Powell. C. Milstein. NCUACS catalogue no.146/3/06 Title: Catalogue of the papers and correspondence of -
Mechanisms of Epigenetics Recap: chromatin structure Each somatic…
https://myheplus.com/uploads/ULzvPvRXfqgav559or4oTqHCLU04lnRAhSNwMiCF.pdf10 Sep 2020: 3. Chromatin conformation plays a role in silencing endogenous viruses incorporated in. -
7400749.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/41_Ashok_A_EMBORep_2006.pdf19 Jun 2006: J Cell Biol 129: 1509–1522. Morita E, Sundquist WI (2004) Retrovirus budding. ... Keywords: prions; retrovirus budding; exosome; endosomal transport;lysosome; multivesicular bodySubmitted 24 May 2006; accepted 31 May 2006. -
Cellular/Molecular Endophilin Drives the Fast Mode of Vesicle…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Llobet%20J%20Neurosci2011.pdf23 Sep 2011: 5C), indicating that the competitive interactionwith endogenous endophilin occurred at the membrane. -
MTP V _forges davanzati_
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Forges/GFD210513.pdf26 Apr 2013: Graziani constructed a basic schema of the working of a monetary economy (see below – section 2), based on the idea that money supply is endogenous and demand-driven. ... These theoretical elements enter the basic schema of the MTP, with particular -
Comments on "The Root Cause of Economic Growthunder…
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Joffe/GI011111.pdf1 Nov 2011: A new micro-fundation of endogenous growth:. Market not a necessary featureCompeting heterogeneous rms is the key. ... Symmetric rms (equilibrium): Endogenous Growth Theory (e.g.Aghion and Howitt, 1992, Grossman and Helpman, 1991, Romer1990). -
Activity 3: Frontiers in light microscopy In the final ...
https://myheplus.com/uploads/VfVhgttiaURBRDsPOB57GC3cN97F8Q96G6OpEFQ8.pdf19 Nov 2020: they work together in an endogenous environment have been obscure.Super-resolution microscopy and single-particle tracking have enabled scientists tobridge that gap. -
An intramembrane chaperone complex facilitates membrane protein…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/wp-content/uploads/sites/8/2020/09/Nature_2020.pdf17 Aug 2020: Endogenous haemoglobin (around 60 kDa) from the translation extract was visualized by Coomassie staining of the same gel. -
sv-lncs
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Werner/RW301012.pdf31 Jul 2012: Towards a New Research Programme on ‘Banking and the Economy’ –. Implications of the Quantity Theory of Credit for the Prevention and Resolution of Banking and Debt Crises. Abstract. The financial crisis has triggered a new consensus among -
d402_16g 822..826
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/15_Hegde_RS_Nature_1999.pdf9 Dec 1999: Trans-genic (Tg) mice expressing each of these mutant PrPs in the FVB/Pmp0/0 background (null for the endogenous PrP gene) weregenerated and characterized (see Table 1 and Fig. -
1 Debt cycles, instability and fiscal rules: A Godley-Minsky ...
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Dafermos/YD200514.pdf1 May 2014: increase in periods of tranquillity as a result of endogenous forces that reduce the. ... private indebtedness. A principal outcome of the analysis was that the endogenous changes in the target. -
Bb9e55.qxd
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Vallis_McMahon1999.pdf21 Mar 2003: Mol Biol Cell 1998, 9:195a. 22. Tuma PL, Stachniak MC, Collins CA: Activation of dynamin GTPaseby acidic phospholipids and endogenous rat brain vesicles. ... such adynaminPH construct into COS cells will be even betterat sequestering endogenous dynamin -
OWN-RATES SRAFFA & KEYNES CH17-3(1)(4)
https://www.robinson.cam.ac.uk/postkeynesian/downloads/Grieve/RG250214.pdf11 Feb 2014: 1. 04/09/04/02 An issue with own-rates: Keynes borrows from Sraffa , Sraffa criticises Keynes,. and present-day commentators get hold of the wrong end of the stick. Roy H Grieve1. Abstract. Scholars who in recent years have studied the Sraffa papers -
elifesciences.org van den Ent et al. eLife 2014;3:e02634. DOI: ...
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/mrebdouble2014.pdf6 Jun 2014: elifesciences.org. van den Ent et al. eLife 2014;3:e02634. DOI: 10.7554/eLife.02634 1 of 22. Bacterial actin MreB forms antiparallel double filamentsFusinita van den Ent1†, Thierry Izoré1†, Tanmay AM Bharat1, Christopher M Johnson2, Jan Löwe1. -
nrm2162.indd
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/17450176.pdf14 Jun 2007: Many plasma-membrane proteins are in a constant flux throughout the internal trafficking pathways of the cell. Some receptors, such as that for transferrin, are continuously internalized into recycling endosomes and returned to the cell surface. -
Activity Answers Activity 1 Task The sequence below is ...
https://myheplus.com/uploads/EgWfnNLym8IUEZJiALoxAmUrHO9bP8PP0DGdF0GZ.pdf10 Sep 2020: 3. True. Endogenous retroviruses comprise 5-8% of the human genome, and they need to be repressed to prevent production of viral RNA and proteins. ... https://en.wikipedia.org/wiki/Bivalent_chromatin. The Atlantic on endogenous retroviruses. -
doi:10.1016/j.molcel.2004.08.030
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Haering%20Mol%20Cell%202004.pdf20 Sep 2004: Cells separatedsister chromatids with identical kinetics to those thatof the GAL1-10 promoter in cells with an endogenous. ... Nevertheless, noncleavableScc1-HA3 from the endogenous SCC1 promoter. The. sole copy of Cdc20 in all three strains was -
Mechanisms of Dense Core Vesicle Recapture following “Kiss andRun” ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Insulin_Tsuboi_JBC2004/Insulin_TsuboiJBC2004.pdf6 Dec 2004: K535A), or amphiphysin-1, all likely tobind to key interacting partners of endogenous dynamin, mightchange the diameter of the fusion pore and thus change thekinetics of tPA or NPY release. -
Clare review MR FILES for web
https://www.clare.cam.ac.uk/sites/default/files/2023-02/Clare-review-MR-FILES-for-web_20190125110840_0.pdf25 Jan 2019: C L A R E C O L L E G EU N I V E R S I T Y O F C A M B R I D G E. 2017 - 2018 | Issue 1. ContentsEditor’sNote. 02. Dear reader,. Edition 36 of Clare News featured. Jonah Surkes, who had just completed. his term as President of the Cambridge. -
53091 361..366
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/McMahonE.pdf3 Dec 2004: endogenous AP2 (middle, AP6 antibody) and transferrin uptake (right). A strong. -
pnas201206839 17424..17429
https://www2.mrc-lmb.cam.ac.uk/groups/rlw/download/publications/23045692.pdf21 Nov 2012: Depletion of endogenous MITD1with two independent small interfering RNAs (siRNAs) resultedin phenotypes consistent with cytokinesis failure, as indicated bya six- to eightfold increase of multinucleated cells compared withcontrol siRNA-transfected -
, 130081, published 7 August 20133 2013 Open Biol. ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/Papers/Open%20Biol.-2013-TakedaCombined.pdf25 Sep 2013: c) D.Mel-2 cells immunostained to reveal endogenous Syndapin (red), Tubulin ( green) and counterstained with DAPI toreveal DNA (blue). ... cleavagefurrow and their effect on cytokinesis upon overexpression inthe presence of endogenous Syndapin. -
The price of free education: Extracting the school quality ...
https://www.christs.cam.ac.uk/sites/default/files/2018-09/Economics-dissertation.pdf25 Sep 2018: 2) No endogenous changes in group composition. Endogenous changes in group composition in difference-in-difference analyses using a repeated cross-section can often bias results. ... This means there isno change in group composition at all, endogenous or -
This document captures the working notes from the workshop ...
https://www.cdbb.cam.ac.uk/files/scoping_workshop_complex_integrated_systems_april_2018_190627.pdf27 Jun 2019: Cambridge. - Operationalisation of CIS. - Context/population endogenous. dynamics needed. - Theoretical developments e.g. ... dynamics, co-evolution, failure of CIS. itself. - ITRC/Mistral/DAFNI- Methods to understand endogenous. -
REPORT◥ PROTEIN HOMEOSTASIS Mechanistic basis for a moleculartriage…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/Science_2017.pdf19 Jan 2017: endogenous proteins with recombinant variantsrevealed the functional roles for all of the factorsand interactions. ... C) Immunoblots (IB) for triage components of control or BAG6 complex-depleted RRL replenished with recombinant BAG6 sub-complexes used -
IntroductionThe endosomal system functions as an internal…
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/SNX2Cullen2005.pdf17 Jan 2006: 5A,B). Furthermore,there was a clear enrichment of endogenous SNX2 on SNX1. ... Cells were then fixed and stained againstendogenous SNX1, endogenous SNX2 and endogenous mVps26. -
Cryo‐EM structure of the full‐length Lon protease from Thermus…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/Lon%20Coscia%202021%20FEBS.pdf14 Nov 2021: the ATP-dependent Lon protease- lessons from. endogenous protein and synthetic peptide substrates. -
Deubiquitinases Sharpen Substrate Discrimination during Membrane…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/82_Zhang_ZR_Cell_2013.pdf5 Aug 2013: Second, the system is typicallyorthogonal to endogenous pathways and utilizes a single definedligase. ... Furthermore, the absolute dependence on phospho-Vpu illustrates that endogenous ligases in this system do notperceive mCD4 as a misfolded protein -
A positively charged channel within the Smc1/Smc3 hinge required for…
https://www2.mrc-lmb.cam.ac.uk/groups/JYL/PDF/embosmcjingekurze2010.pdf1 Dec 2010: together with endogenous Smc3. Western blotting revealed. that immunoprecipitates of Smc3-HA3 or Smc3AAA-HA3. ... As expected, similar amounts of Smc1-myc9 and endogenous. Smc1 associate with Smc3-HA3. -
Molecular Biology of the CellVol. 8, 2003–2015, October 1997 ...
https://www2.mrc-lmb.cam.ac.uk/groups/hmm/publica/WiggeKohler_McMahon1997.pdf10 Oct 1997: We interpret these results tomean that either Amph1 or Amph2 overexpressionalone leads to sequestration of endogenous dynamininto inactive complexes, but when the two proteins areexpressed together, forming a heterodimer, endocyto-sis -
Protein targeting and degradation are coupled for elimination of…
https://www2.mrc-lmb.cam.ac.uk/groups/hegde/download/73_Hessa_T_Nature_2011.pdf14 Jul 2011: endogenous ubiqui-tin was more than 90% competed out, resulting in few or no untagged ubiquiti-nated products. ... The absence of endogenous charged tRNAs and haemoglobinincreased photocrosslinker incorporation and photolysis, respectively.
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