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21 - 30 of 53 search results for p53

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  2. Greta Skrupskelyte | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/great-skrupskelyte
    23 Feb 2024: 2018) Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.

  3. Dr Ingo Ringshausen - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/dr-ingo-ringshausen/
    23 Feb 2024: Swigart, and G.I. Evan. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Finch, L.B. Swigart, and G.I. Evan. Thepathological response to DNA damage does not contribute to p53-mediated tumour suppression.

  4. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/brian-huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  5. Publications - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/publications/
    23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.

  6. Professor Margaret Ashcroft | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft
    23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

  7. Dr Pentao Liu | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk
    23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some

  8. CBSB - Tissue bank and blood collection in Cambridge

    https://www.haem.cam.ac.uk/cambridge-blood-and-stem-cell-biobank/
    23 Feb 2024: Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.

  9. Catherine Perry - Department of Public Health and Primary Care

    https://www.phpc.cam.ac.uk/people/ceu-group/ceu-research-staff/catherine-perry/
    23 Feb 2024: P53 Epidemiological evidence to support a tax on Sugar Sweetened Drinks as a measure to address childhood obesity.

  10. Dr Rémi B. Fiancette | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/fiancette
    23 Feb 2024: and Denizot Y., 2012, Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. ... Magnone V., Cogné M. and Denizot Y., 2011, A p53 defect sensitizes

  11. https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6

    https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6
    23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

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