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21 - 30 of 66 search results for p53

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  2. Research News Archives - Page 12 of 29 - School of Clinical Medicine

    https://www.medschl.cam.ac.uk/category/schoolnews/research-news/page/12/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  3. Dr Maria Christophorou | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/christophorou
    23 Feb 2024: She did her PhD with Gerard Evan at UCSF, where she was able to dissect the relative contributions of different p53 activating signals towards tumour suppression using mouse models of conditional ... p53 perturbation.

  4. https://www.med.cam.ac.uk/rana/wp-json/wp/v2/pages/26

    https://www.med.cam.ac.uk/rana/wp-json/wp/v2/pages/26
    23 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-01-12T14:44:42","modified_gmt":"2015-01-12T14:44:42","slug":"publications","status"

  5. Professor Alan Warren | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/warren
    23 Feb 2024: consequence of p53 stabilization in response to ribosomal stress.

  6. https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/26

    https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/26
    23 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-02-06T11:14:05","modified_gmt":"2015-02-06T11:14:05","slug":"publications","status"

  7. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/brian-huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  8. Professor Margaret Ashcroft | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft
    23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

  9. Dr Pentao Liu | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk
    23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some

  10. CBSB - Tissue bank and blood collection in Cambridge

    https://www.haem.cam.ac.uk/cambridge-blood-and-stem-cell-biobank/
    23 Feb 2024: Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.

  11. Catherine Perry - Department of Public Health and Primary Care

    https://www.phpc.cam.ac.uk/people/ceu-group/ceu-research-staff/catherine-perry/
    23 Feb 2024: P53 Epidemiological evidence to support a tax on Sugar Sweetened Drinks as a measure to address childhood obesity.

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