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  2. Early human development and the germline (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/early_human_development_and_the_germline_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:16pm, 25 Apr 2024 Page 3 of 6. journals to benefit advances in the field. ... Downloaded: 9:16pm, 25 Apr 2024 Page 4 of 6. What will happen to animals at the end of this project?
  3. Models of mitochondrial diseases, pathogenesis and therapy

    https://www.ubs.admin.cam.ac.uk/system/files/public/models_of_mitochondrial_diseases_pathogenesis_and_therapy_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:15pm, 25 Apr 2024 Page 3 of 8. Who or what will benefit from these outputs, and how? ... Downloaded: 9:15pm, 25 Apr 2024 Page 7 of 8. Mice will be used to model human mitochondrial diseases.
  4. Generation and screening of companion animal therapeutics.…

    https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:48pm, 25 Apr 2024 Page 3 of 17. immunoglobulin heavy and light chain genes. ... Downloaded: 9:48pm, 25 Apr 2024 Page 14 of 17. to use in breeding.
  5. Cancer and its microenvironment! From mechanisms to translation…

    https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:18pm, 25 Apr 2024 Page 3 of 16. 1. The tumour microenvironment (TME). ... Downloaded: 9:18pm, 25 Apr 2024 Page 12 of 16. If necessary, we will consult statisticians based in our Institution.
  6. Control of equine herpesviruses in the horse

    https://www.ubs.admin.cam.ac.uk/system/files/public/control_of_equine_herpesviruses_in_the_horse._non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:01pm, 25 Apr 2024 Page 4 of 11. Unfortunately, the use of ponies for our research is essential. ... Downloaded: 9:01pm, 25 Apr 2024 Page 7 of 11. replicate to reduce the chances having a non-responding blood donor.
  7. Mechanisms underpinning neuronal excitability in health and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_underpinning_neuronal_excitability_in_health_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:26pm, 25 Apr 2024 Page 8 of 14. Why do you need to use animals to achieve the aim of your project? ... Downloaded: 9:26pm, 25 Apr 2024 Page 10 of 14. Overall numbers have been estimated based upon two key factors:. •
  8. Interaction between the immune system and tumours (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interaction_between_the_immune_system_and_tumours_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:43pm, 25 Apr 2024 Page 2 of 8. Description of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing. ... Downloaded: 9:43pm, 25 Apr 2024 Page 8 of 8. can take weeks or months not
  9. Early life origins of heart disease in mammals (non-technical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/early_life_origins_of_heart_disease_in_mammals_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:25pm, 25 Apr 2024 Page 3 of 12. in different vessels (e.g. ... Downloaded: 9:25pm, 25 Apr 2024 Page 5 of 12. subsequent molecular studies).
  10. Mouse developmental genetics to study neurodevelopment and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mouse_developmental_genetics_to_study_neurodevelopment_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:31pm, 25 Apr 2024 Page 3 of 10. regeneration in the human brain. ... Downloaded: 9:31pm, 25 Apr 2024 Page 7 of 10. normal development and disease.
  11. Breeding and maintenance of rodents for drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 8:46pm, 25 Apr 2024 Page 3 of 9. drugs further along the drug discovery pipeline. ... Downloaded: 8:46pm, 25 Apr 2024 Page 9 of 9. recorded if there are any signs of ill health.
  12. The diversity of glia in health, development and disease…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_diversity_of_glia_in_health_development_and_disease_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:38pm, 25 Apr 2024 Page 2 of 11. Contains severe procedures. ... Downloaded: 9:38pm, 25 Apr 2024 Page 9 of 11. is on understanding adult mechanisms.
  13. Neural, physiological and behavioural mechanisms underlying cognition …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neural_physiological_and_behavioural_mechanisms_underlying_cognition_and_emotion_non-technical_sum_redacted.pdf
    30 Apr 2024: Downloaded: 9:22pm, 25 Apr 2024 Page 9 of 15. Why were they not suitable? ... Downloaded: 9:22pm, 25 Apr 2024 Page 11 of 15. running the main study.
  14. Neurobehavioural Mechanisms Underlying Mood, Anxiety and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_anxiety_and_stress-related_mental_health_disorders_non_redacted.pdf
    30 Apr 2024: Downloaded: 9:42pm, 25 Apr 2024 Page 2 of 10. Reason for retrospective assessment. ... Downloaded: 9:42pm, 25 Apr 2024 Page 8 of 10. funding at similar levels.
  15. Epigenetic inheritence and the control of developmental and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf
    30 Apr 2024: Downloaded: 8:59pm, 25 Apr 2024 Page 3 of 10. Who or what will benefit from these outputs, and how? ... Downloaded: 8:59pm, 25 Apr 2024 Page 4 of 10. Mice and zebrafish are used to investigate aspects of our studies.
  16. INTER ALIOS. T h e J o i n ...

    https://chapel.chu.cam.ac.uk/wp-content/uploads/sites/6/2024/04/Easter-Term-Card-2023-24.pdf
    25 Apr 2024: Scholarship with Murray Edwards or Churchill, please contact:. Director of Music – Dr Ewan Campbell, eahc2@cam.ac.uk.
  17. Discovery and development of treatments for immunological diseases

    https://www.ubs.admin.cam.ac.uk/system/files/public/discovery_and_development_of_treatments_for_immunological_diseases_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:04pm, 25 Apr 2024 Page 2 of 8. Objectives and benefitsDescription of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing. ... Downloaded: 9:04pm, 25 Apr 2024 Page 4 of 8. compared to
  18. Pharmacological evaluation of imaging agents and development of…

    https://www.ubs.admin.cam.ac.uk/system/files/public/pharmacological_evaluation_of_imaging_agents_and_development_of_imaging_applications_and_methods_no_redacted.pdf
    30 Apr 2024: Downloaded: 9:45pm, 25 Apr 2024 Page 3 of 11. 2. Biological evaluation. ... Downloaded: 9:45pm, 25 Apr 2024 Page 7 of 11. Non-recovery: 75%.
  19. Vaccine development and fundamental reseach on viruses of medical…

    https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:20pm, 25 Apr 2024 Page 2 of 12. Animal types Life stages. ... Downloaded: 9:20pm, 25 Apr 2024 Page 5 of 12. observed for a period of up to 14 days.
  20. Environmental and placental contributions to pregnancy and life-long…

    https://www.ubs.admin.cam.ac.uk/system/files/public/environmental_and_placental_contributions_to_pregnancy_and_life-long_health_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:14pm, 25 Apr 2024 Page 4 of 14. later life health problems based on this study. ... Downloaded: 9:14pm, 25 Apr 2024 Page 10 of 14. analyses (e.g.
  21. Neurobehavioural Mechanisms Underlying Mood, Impulsive and Compulsive …

    https://www.ubs.admin.cam.ac.uk/system/files/public/neurobehavioural_mechanisms_underlying_mood_impulsive_and_compulsive_mental_health_disorders_non-t_redacted.pdf
    30 Apr 2024: Downloaded: 9:20pm, 25 Apr 2024 Page 4 of 8. measurements (e.g. ... Downloaded: 9:20pm, 25 Apr 2024 Page 5 of 8. Early life stress produces extended (i.e.
  22. Developing new mulivalent recombinant vaccines platforms against…

    https://www.ubs.admin.cam.ac.uk/system/files/public/developing_new_multivalent_recombinant_vaccines_platforms_against_infectious_diseases._non-technic_redacted.pdf
    29 Apr 2024: Downloaded: 9:06pm, 25 Apr 2024 Page 5 of 8. Mice:. Mild=96%. ... Downloaded: 9:06pm, 25 Apr 2024 Page 8 of 8. that allows more accurate dosing and reproducibility of results.
  23. Exploring Bioelectronic Approaches to Nervous System Restoration in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/exploring_bioelectronic_approaches_to_nervous_system_restoration_in_large_animals_non-technical_sum_redacted.pdf
    30 Apr 2024: Downloaded: 9:30pm, 25 Apr 2024 Page 2 of 10. The Secretary of State has determined that a retrospective assessment of this licence is notrequired. ... Downloaded: 9:30pm, 25 Apr 2024 Page 6 of 10. Because of these reasons, we need to use animals for our
  24. Determining mechanisms of tumour development and relapse following…

    https://www.ubs.admin.cam.ac.uk/system/files/public/determining_mechanisms_of_tumour_development_and_relapse_following_treatment_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:12pm, 25 Apr 2024 Page 7 of 11. Which non-animal alternatives did you consider for use in this project? ... Downloaded: 9:12pm, 25 Apr 2024 Page 11 of 11. randomly assigned to treatment groups and attempts will be made to blind studies.
  25. Mechanisms controlling cell division and cell identity during…

    https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_controlling_cell_division_and_cell_identity_during_development_reprogramming_and_disease_redacted.pdf
    30 Apr 2024: Downloaded: 9:22pm, 25 Apr 2024 Page 3 of 7. effectively reprogram cells into specific types. ... Downloaded: 9:22pm, 25 Apr 2024 Page 5 of 7. study cell fate most easily and efficiently.
  26. Jesus College

    https://www.jesus.cam.ac.uk/sites/default/files/vacancy_download/application_form_-_new_0_3.pdf
    1 May 2024: Please account for any. period which you were not employed. If you need more space, please attach additional pages/notes.
  27. Jesus College

    https://www.jesus.cam.ac.uk/sites/default/files/vacancy_download/application_form_-_new_0_2.pdf
    1 May 2024: Please account for any. period which you were not employed. If you need more space, please attach additional pages/notes.
  28. Jesus College

    https://www.jesus.cam.ac.uk/sites/default/files/vacancy_download/application_form_-_new_0_1.pdf
    1 May 2024: Please account for any. period which you were not employed. If you need more space, please attach additional pages/notes.
  29. Trinity College Typical Rooms Booklet

    https://www.trin.cam.ac.uk/download/typical-accommodation-undergraduates/?wpdmdl=3035&refresh=668a669a05e881720346266
    9 May 2024: The links in the College Plan on this page will take you to information about typical rooms available in each area, as well as the groups of students who are eligible
  30. Trinity College Typical Rooms Booklet

    https://www.trin.cam.ac.uk/download/typical-accommodation-undergraduates/?wpdmdl=3035&refresh=668a57e569f581720342501
    9 May 2024: The links in the College Plan on this page will take you to information about typical rooms available in each area, as well as the groups of students who are eligible
  31. Understanding the roles of autophagy and related pathways in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/understanding_the_roles_of_autophagy_and_related_pathways_in_proteinopathies_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:11pm, 25 Apr 2024 Page 3 of 11. Who or what will benefit from these outputs, and how? ... Downloaded: 9:11pm, 25 Apr 2024 Page 4 of 11. Our choice of species for this licence is mice.
  32. Development of humanised mouse models for study of cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf
    29 Apr 2024: Downloaded: 9:07pm, 25 Apr 2024 Page 2 of 8. Description of the projects objectives, for example the scientific unknowns or clinical orscientific needs it's addressing. ... Downloaded: 9:07pm, 25 Apr 2024 Page 7 of 8. 2) Reconstitution of the animals
  33. Investigating the niche of mucosal parasitic nematodes and their…

    https://www.ubs.admin.cam.ac.uk/system/files/public/investigating_the_niche_of_mucosal_parasitic_nematodes_and_their_interactions_with_their_hosts_non_redacted.pdf
    30 Apr 2024: Downloaded: 9:19pm, 25 Apr 2024 Page 11 of 12. - Carefully consider needle gauge, and keeping volumes and doses to the minimum necessary, for injection of substances. - ... Downloaded: 9:19pm, 25 Apr 2024 Page 12 of 12. RSPCA website: http://science.rspca
  34. Development of Live Bacterial Therapeutics to treat diseases with…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_live_bacterial_therapeutics_to_treat_diseases_with_intestinal_dysbiosis_non-technica_redacted.pdf
    29 Apr 2024: Downloaded: 9:12pm, 25 Apr 2024 Page 5 of 8. What will happen to animals at the end of this project? ... Downloaded: 9:12pm, 25 Apr 2024 Page 7 of 8. Which animal models and methods will you use during this project?
  35. Interventions in pregnancy effects of obesity on maternal and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf
    30 Apr 2024: Downloaded: 8:52pm, 25 Apr 2024 Page 8 of 13. the mouse's tail. ... Downloaded: 8:52pm, 25 Apr 2024 Page 10 of 13. objectives, if any.
  36. The genetic and developmental basis of morphological and behavioural…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_genetic_and_developmental_basis_of_morphological_and_behavioural_variation_in_cichlid_fishes_no_redacted.pdf
    30 Apr 2024: Downloaded: 9:46pm, 25 Apr 2024 Page 6 of 11. dividers will have holes where females can go through. ... Downloaded: 9:46pm, 25 Apr 2024 Page 7 of 11. we do not expect this protocol to induce any suffering, harm or distress.
  37. PK and PKPD studies to support Respiratory and Immunology research

    https://www.ubs.admin.cam.ac.uk/system/files/public/pk_and_pkpd_studies_to_support_respiratory_and_immunology_research_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 9:08pm, 25 Apr 2024 Page 4 of 8. development is very rapid and animals become sexually mature in a matter of weeks. ... Downloaded: 9:08pm, 25 Apr 2024 Page 5 of 8. What are the expected severities and the proportion of animals in each
  38. Development of Molecular Imaging and Theranostic Agents for Cancer…

    https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_molecular_imaging_and_theranostic_agents_for_cancer_and_inflammation_non-technical_s_redacted.pdf
    30 Apr 2024: Downloaded: 9:17pm, 25 Apr 2024 Page 4 of 9. develop new and/or improved agents in this arena. ... Downloaded: 9:17pm, 25 Apr 2024 Page 9 of 9. (AALAS) American Association for Laboratory Animals Science.
  39. CNS Neuron-glia interactions, myelin plasticity, and regeneration, in …

    https://www.ubs.admin.cam.ac.uk/system/files/public/cns_neuron-glia_interactions_myelin_plasticity_and_regeneration_in_health_and_disease_non-techni_redacted.pdf
    30 Apr 2024: Downloaded: 9:37pm, 25 Apr 2024 Page 2 of 15. Contains severe procedures. ... Downloaded: 9:37pm, 25 Apr 2024 Page 7 of 15. and completely from the first procedure.
  40. Genes and environment at the interface of inflammation, immunity and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/genes_and_environment_at_the_interface_of_inflammation_immunity_and_metabolism_non-technical_summa_redacted.pdf
    30 Apr 2024: Downloaded: 9:02pm, 25 Apr 2024 Page 2 of 11. What's the aim of this project? ... Downloaded: 9:02pm, 25 Apr 2024 Page 7 of 11. mouse the most appropriate model system.
  41. Provision of an outsourced drug discovery platform for metabolic and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_metabolic_and_cardiovascular_diseases_non-te_redacted.pdf
    30 Apr 2024: Downloaded: 8:55pm, 25 Apr 2024 Page 6 of 12. relief if needed. ... Downloaded: 8:55pm, 25 Apr 2024 Page 7 of 12. Mouse - Moderate: 62%.
  42. Profiling of test agents in rodents in a drug discovery platform

    https://www.ubs.admin.cam.ac.uk/system/files/public/profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf
    30 Apr 2024: Downloaded: 8:56pm, 25 Apr 2024 Page 7 of 12. For biodistribution studies, animals will be dosed with test agent(s) once or several times. ... Downloaded: 8:56pm, 25 Apr 2024 Page 8 of 12. important as it allows decisions to be made on the doses for all
  43. Remodelling of stem cells and niche cells from development and…

    https://www.ubs.admin.cam.ac.uk/system/files/public/remodelling_of_stem_cells_and_niche_cells_from_development_and_regeneration_to_disease_non-technic_redacted.pdf
    30 Apr 2024: Downloaded: 9:04pm, 25 Apr 2024 Page 8 of 13. the animal in any way. ... Downloaded: 9:04pm, 25 Apr 2024 Page 11 of 13. the animal technicians prior to use.
  44. Provision of an outsourced drug development platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_development_platform_for_the_treatment_of_bleeding_disorders_non-te_redacted.pdf
    30 Apr 2024: Downloaded: 9:29pm, 25 Apr 2024 Page 2 of 12. Reason for retrospective assessment. ... Downloaded: 9:29pm, 25 Apr 2024 Page 11 of 12. if preventative treatments are being tested.
  45. Tissue response following synovial joint injury and potential for…

    https://www.ubs.admin.cam.ac.uk/system/files/public/tissue_response_following_synovial_joint_injury_and_potential_for_therapies_to_restore_joint_structu_redacted.pdf
    30 Apr 2024: Downloaded: 8:57pm, 25 Apr 2024 Page 4 of 8. Typically, what will be done to an animal used in your project? ... Downloaded: 8:57pm, 25 Apr 2024 Page 6 of 8. How have you estimated the numbers of animals you will use?
  46. Multi-tissue mechanics in the development and engineering of the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/multi-tissue_mechanics_in_the_development_and_engineering_of_the_posterior_body_axis_non-technical_redacted.pdf
    30 Apr 2024: Downloaded: 9:40pm, 25 Apr 2024 Page 2 of 9. What's the aim of this project? ... Downloaded: 9:40pm, 25 Apr 2024 Page 6 of 9. dish (in vitro).
  47. Extrinsic regulation of haematopoietic stem and progenitor cells in…

    https://www.ubs.admin.cam.ac.uk/system/files/public/extrinsic_regulation_of_haematopoietic_stem_and_progenitor_cells_in_health_disease_and_as_a_therape_1_redacted.pdf
    30 Apr 2024: Downloaded: 9:40pm, 25 Apr 2024 Page 7 of 13. KilledUsed in other projectsKept alive. ... Downloaded: 9:40pm, 25 Apr 2024 Page 8 of 13. ReductionExplain how the numbers of animals for this project were determined.
  48. The development of novel therapies (including cell and gene based…

    https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_novel_therapies_including_cell_and_gene_based_approaches_for_parkinsons_and_hu_redacted.pdf
    30 Apr 2024: Downloaded: 9:47pm, 25 Apr 2024 Page 7 of 10. Which non-animal alternatives did you consider for use in this project? ... Downloaded: 9:47pm, 25 Apr 2024 Page 8 of 10. To minimise animal usage, we will:.
  49. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_canc_redacted.pdf
    30 Apr 2024: Downloaded: 8:53pm, 25 Apr 2024 Page 11 of 13. Why can’t you use animals that are less sentient? ... Downloaded: 8:53pm, 25 Apr 2024 Page 13 of 13. animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report.
  50. Provision of an outsourced drug discovery platform for the…

    https://www.ubs.admin.cam.ac.uk/system/files/public/provision_of_an_outsourced_drug_discovery_platform_for_the_development_of_therapeutic_drugs_for_neur_redacted.pdf
    30 Apr 2024: Downloaded: 9:00pm, 25 Apr 2024 Page 3 of 10. needs for treatments. ... Downloaded: 9:00pm, 25 Apr 2024 Page 9 of 10. costs (harms) to the animals.
  51. CLARE HALL, CAMBRIDGE 1 CLARE HALL, CAMBRIDGE CB3 9AL ...

    https://www.clarehall.cam.ac.uk/wp-content/uploads/2024/05/CLARE-HALL-ORDINANCES-2023-Final.pdf
    9 May 2024: The Fellowship Committee shall make recommendations to the Governing Body on the following matters: Elections and Re-elections to Research Fellowships Elections to Visiting Fellowships and Guest Scholarships Elections to Affiliated

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