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https://www.citiid.cam.ac.uk/feed/
https://www.citiid.cam.ac.uk/feed/18 Jan 2024: May 2022 17:17:35 0000 Featured news News https://www.citiid.cam.ac.uk/?p=9026 Executive summary The Modis Group has found an endogenous retrovirus in hookworm with an -
PhD & postdoc Seminars | Wellcome-MRC Cambridge Stem Cell…
https://www.stemcells.cam.ac.uk/events/phd-postdoc-seminars23 Feb 2024: Stephen Loughran, postdoc, Green lab. "JAK2 phosphorylates the RNA binding protein HNRNPA1 to repress endogenous retrovirus expression and protect haematopoiesis". -
Publications | Coleman Laboratory
https://colemanlab.brc.cam.ac.uk/publications23 Feb 2024: 2020) Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors. ... 2010) Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons. -
Churchill College Alumnus awarded Humboldt Prize for World-leading…
https://www.chu.cam.ac.uk/news/news-and-events/churchill-college-alumnus-awarded-humboldt-prize-for-world-leading-evolutionary-genetics-research/26 Mar 2024: I was wondering how to examine this and noticed something odd: several hundred copies of a fairly new (to our genome) endogenous retrovirus (ERV) were all active in early human embryos Results that match 1 of 2 words
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vsvg_pseudtyped_retrovirus_101209_0clip_image002.png | Ron Lab
https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage002png23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image002.png. 2024 University of Cambridge. -
Yorgo Modis
https://www.citiid.cam.ac.uk/yorgo-modis/23 Feb 2024: Key Research Questions. How do cells distinguish pathogenic viral nucleic acids from non-pathogenic endogenous nucleic acids? ... Pathogenic viral and non-pathogenic endogenous nucleic acids are often difficult to distinguish. -
Home - Professor Morrell's Group
https://www.med.cam.ac.uk/morrell/23 Feb 2024: Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary -
Dr Li's Group
https://www.med.cam.ac.uk/li/23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Prof Anthony Davenport | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/adavenport23 Feb 2024: In first in human, proof of principle studies, MM07 was a more efficacious dilator in human forearm and hand vein via the G-protein mediated pathway than the endogenous peptides. ... and Maguire, J,J. (2017) [Pyr. 1. ]Apelin-13. (1-12). is a biologically -
BHF Oxbridge CRM Introduction | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/research/oxbridgecrm23 Feb 2024: To harness the capacity of endogenous stem cell and progenitor cells for repair and regeneration. -
John Sinclair
https://www.citiid.cam.ac.uk/john-sinclair/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Site Search. Site Search. John Sinclair. Cambridge Institute of Therapeutic Immunology & Infectious -
Nicole C Kaneider
https://www.citiid.cam.ac.uk/nicole-kaneider/22 Feb 2024: However, GPR35’s endogenous, relevant ligands and the receptor’s function remain enigmatic. We recently discovered that GPR35 regulates the cell’s ion homeostasis, its metabolic and proliferative activity by interacting -
Publications - Professor Bennett's Group
https://www.med.cam.ac.uk/bennett/publications/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Professor Bennett's Group. Publications. Links. 2024 University of Cambridge. -
Irene Cimino - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/irene-cimino/23 Feb 2024: Activation of the Hypothalamic-Pituitary-Adrenal axis by exogenous and endogenous GDF15. PNAS July 6, 2021, 118 (27) e2106868118;. -
Dr Fotios Sampaziotis | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/pi/sampaziotis23 Feb 2024: endogenous regeneration as a therapeutic strategy to repair duct damage. ... We are trying to understand why this mechanism fails in disease and identify therapeutics modifying the cells’ microenvironment to promote endogenous regeneration. -
Loraine Tung - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/loraine-tung/23 Feb 2024: 2021) Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. -
DiscoverX European GPCR Symposium 2016 - 12 April - School of…
https://www.medschl.cam.ac.uk/gpcr-symposium-12-april/23 Feb 2024: Dr Elizabeth M Rosethorne, Snr Research Fellow, University of Nottingham. Identification of Endogenous and Surrogate Ligands for Orphan GPCRs – Through Computational Drug Design Methods. -
Debra Rimmington - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/debra-rimmington/23 Feb 2024: Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proc Natl Acad Sci U S A. -
Poster Abstracts | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/poster-abstracts23 Feb 2024: Background: The apelin receptor, a class A GPCR, binds two endogenous peptide ligands, apelin and ELA, to induce potent vasodilatation and increase cardiac output. ... Considering these limitations, we are developing a novel method for stimulating -
vsvg_pseudtyped_retrovirus_101209_0clip_image004.png | Ron Lab
https://ron.cimr.cam.ac.uk/file/vsvgpseudtypedretrovirus1012090clipimage004png23 Feb 2024: Search site. Ron Lab. vsvg_pseudtyped_retrovirus_101209_0clip_image004.png. 2024 University of Cambridge. -
Dr Wei Li | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/wli23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Research
https://www.med.cam.ac.uk/li/research/23 Feb 2024: We also show that loss of endogenous BMP9 leads to lung vascular leak in vivo, and have developed BMP9 variants that maintain endothelial protective function but lack the bone-forming activity. -
Dr Janet Maguire | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/jmaguire23 Feb 2024: Pyr. 1. ]apelin-13. (1-12). is a biologically active ACE2 metabolite of the endogenous cardiovascular peptide [Pyr. ... Elabela/Toddler is an endogenous agonist of the apelin APJ receptor in the adult cardiovascular system, and exogenous administration -
Robyn Macrae | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/robyn-macrae23 Feb 2024: Title: The apelin signalling system is composed of the G-protein coupled apelin receptor and its two endogenous peptide ligands, apelin and Elabela/Toddler (ELA). ... Structure and pharmacology of the apelin receptor with a recommendation that -
Dr Andrew Sage | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/asage23 Feb 2024: Recently, our lab defined the direct overall contribution of endogenous antibodies to atherosclerosis in a fully immunocompetent model. -
Professor Robert Glen | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/rglen23 Feb 2024: FAst MEtabolizer (FAME): A rapid and accurate predictor of sites of metabolism in multiple species by endogenous enzymes. -
Professor Guy Brown | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/gbrown23 Feb 2024: Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease. -
Professor Colin Taylor | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/ctaylor23 Feb 2024: Endogenous signalling pathways and caged-IP. 3. evoke Ca. 2+. puffs at the same abundant immobile intracellular sites. -
https://www.medschl.cam.ac.uk/tag/hormones/feed/
https://www.medschl.cam.ac.uk/tag/hormones/feed/23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute -
Dr William McEwan | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/william23 Feb 2024: Person keywords:. neutralisation. adenovirus. retrovirus. virus. intracellular immunity. antibody. Contact us. -
Cambridge Clinical Multiple Sclerosis Research
https://www-neurosciences.medschl.cam.ac.uk/cambridge-clinical-ms-research/23 Feb 2024: Investigating natural remyelination in people with MS. Doing clinical trials to identify drugs which promote endogenous remyelination in people with MS. -
Publications - Professor Morrell's Group
https://www.med.cam.ac.uk/morrell/publications/23 Feb 2024: Elabela/Toddler is an Endogenous Agonist of the Apelin APJ receptor in the adult cardiovascular system, and exogenous administration of the peptide compensates for the downregulation of its expression in pulmonary -
Dr Joseph Cheriyan | Cambridge Cardiovascular
https://www.cardiovascular.cam.ac.uk/directory/jcheriyan23 Feb 2024: Pyr1]Apelin-13(1-12) Is a Biologically Active ACE2 Metabolite of the Endogenous Cardiovascular Peptide [Pyr1]Apelin-13. -
https://www.medschl.cam.ac.uk/tag/endocrinology/feed/
https://www.medschl.cam.ac.uk/tag/endocrinology/feed/23 Feb 2024: dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell from the Institute -
The power of hormones on the world’s trading floors - School of…
https://www.medschl.cam.ac.uk/power-hormones-worlds-trading-floors/23 Feb 2024: By using personalised dosing schedules, we have been able to closely replicate the changes in endogenous cortisol levels observed in traders during periods of increased market volatility,” says Dr Mark Gurnell -
Professor Paul Lehner | Wellcome-MRC Cambridge Stem Cell Institute
https://www.stemcells.cam.ac.uk/people/affiliates/lehner23 Feb 2024: Remarkably HUSH also silences endogenous mobile retrotransposons like LINE-1 elements, which make up 17% of our genome. -
Methods Passmore Lab
https://www2.mrc-lmb.cam.ac.uk/groups/passmore/Methods.html5 Jan 2024: tag endogenous genes in human cells. -
Publications - Clinical Gerontology
https://www.phpc.cam.ac.uk/gerontology/publications/23 Feb 2024: Endogenous sex hormones and endometrial cancer risk in women in the European Prospective Investigation into Cancer and Nutrition ( EPIC ). Endocr Relat Cancer. 2008 Jun;15(2):485-497. Rohrmann S, Linseisen ... Endogenous androgens and risk of epithelial -
Professor Jon Yewdell | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/yewdell23 Feb 2024: 2012). MHC class I antigen processing distinguishes endogenous antigens based on their translation from cellular vs. ... 2012). Endogenous viral antigen processing generates peptide-specific MHC class I cell-surface clusters. -
Joshua Bernstock | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/bernstock23 Feb 2024: Endogenous NPCs subsequently migrate toward the ischemic lesion where they promote tissue remodeling and neural repair. ... restorative responses initially executed by the endogenous NPC population. We claim that understanding these immunomodulatory -
Dr Nicholas Matheson | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/njm25%40cam.ac.uk23 Feb 2024: host-pathogen interaction. proteomics. retrovirus. immunobiology. SILAC. metabolism. Contact us. Cambridge Immunology Network Coordinator. -
Professor Jonathan Luke Heeney | Cambridge Immunology Network
https://www.immunology.cam.ac.uk/Networkdirectory/heeney23 Feb 2024: virology. innate immunity. retrovirus. Immunosenescence. Calcivirus RNA viruses. Immune-ageing. Contact us. -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/7/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/7/feed23 Feb 2024: Structure and pharmacology of the apelin receptor with a recommendation that Elabela/Toddler is a second endogenous peptide ligand. -
https://www.cardiovascular.cam.ac.uk/taxonomy/term/30/feed
https://www.cardiovascular.cam.ac.uk/taxonomy/term/30/feed23 Feb 2024: of metabolism in multiple species by endogenous enzymes.</a> Kirchmair J, Williamson MJ, Afzal AM, Tyzack JD, Choy AP, Howlett A, Rydberg P, <b>Glen RC</b>.<span class="jrnl" -
Anthony Coll - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/research/principal-investigators/anthony-coll/23 Feb 2024: Activation of the hypothalamic-pituitary-adrenal axis by exogenous and endogenous GDF15. Proc Natl Acad Sci U S A. -
Dr Anthony Davenport - EMIT
https://emit.medschl.cam.ac.uk/people/investigators/dr-anthony-davenport/23 Feb 2024: The peptide apelin is the endogenous ligand for a novel G-protein coupled receptor with an emerging key role in cardiovascular disease. ... and Maguire, J,J. (2017) [Pyr. 1. ]Apelin-13. (1-12). is a biologically Active ACE2 Metabolite of the Endogenous -
On detection of ER stress | Ron Lab
https://ron.cimr.cam.ac.uk/detection-er-stress23 Feb 2024: 2003 February; 23(4): 1292–1303) in which they report on the successful application of the SCBT anti-GADD34 H-193 serum to stain endogenous GADD34 in NIH 3T3 cells. ... We were unable to detect the endogenous XBP-1 with the SC-8015 monoclonal antiserum) -
Publications - Institute of Metabolic Science-Metabolic Research…
https://www.mrl.ims.cam.ac.uk/research/publications/23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Site Search. Site Search. Publications. Institute of Metabolic Science-Metabolic Research Laboratories. -
Joe Herbert - John van Geest Centre for Brain Repair
https://www.brc.cam.ac.uk/principal-investigators/joe-herbert/23 Feb 2024: Eur. J. Neursci. 27, 2493-500. Coates JM, Herbert J (2008) Endogenous steroids and financial risk taking on a London trading floor. -
Blue Sky Collaboration - MRC Laboratory of Molecular Biology
https://www2.mrc-lmb.cam.ac.uk/research/blue-sky-collaboration/10 Jan 2024: A Method for the Acute and Rapid Degradation of Endogenous Proteins.
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