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23 Feb 2024: necrosis factor-alpha therapy for severe enteropathy in patients with common variable immunodeficiency (CVID). ... The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to

23 Feb 2024: Project number: 657633. Project acronym: DecipherBILU. Project title: Understanding functional mechanisms leading to the BILU syndrome. ... Primary immunodeficiencies (PIDs) are a heterogeneous group of disorders often caused by monogenic mutations that

23 Feb 2024: Search site. Cambridge Immunology Network. Professor Jonathan Luke Heeney. Vaccine induced immunity. ... Immune correlates of natural and vaccine induced immunity. Viral evasion of host responses.

23 Feb 2024: {"id":266,"date":"2017-06-21T15:24:14","date_gmt":"2017-06-21T14:24:14","guid":{"rendered":"http://www.med.cam.ac.uk/nejentsev/?page_id=266"},"modified":"2017-06-21T15:33:36","modified_gmt":"2017-06-21T14:33:36","slug":"decipherbilu","status":"publis

23 Feb 2024: Genetic analyses of patients with Primary Immunodeficiencies. Primary Immunodeficiencies (PIDs) comprise a heterogeneous group of genetic disorders that affect functioning of the immune system and manifest as severe and/or recurrent ... Recently, we

23 Feb 2024: model of the human immunodeficiency, Activated PI3Kinase δ syndrome (APDS).

23 Feb 2024: model of the human immunodeficiency, Activated PI3Kinase δ syndrome (APDS).

23 Feb 2024: Search site. Cambridge Immunology Network. Dr Helen Baxendale. B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Vaccine 2010; 28: 6915-22. Baxendale HE, Keating

23 Feb 2024: model of the human immunodeficiency, Activated PI3Kinase δ syndrome (APDS).

23 Feb 2024: Vaccine 2010; 28: 6915-22.</p> <p>Baxendale HE, Keating SM, Johnson M, Southern J, Miller E, Goldblatt D. ... class="field-label">Research interests:&nbsp;</div><div class="field-items"><div class="field-item even"><p>B cell lineage and repertoire

23 Feb 2024: {"id":6,"date":"2011-03-01T11:55:15","date_gmt":"2011-03-01T11:55:15","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=6"},"modified":"2015-02-24T14:33:58","modified_gmt":"2015-02-24T14:33:58","slug":"research","status":"publ

23 Feb 2024: The team is also characterising the virology of key spike protein mutations in new variants and their impact on natural and vaccine induced immunity. ... Simian Immunodeficiency Virus envelope glycoprotein counteracts tetherin/BST-2/CD317 by

23 Feb 2024: Primary Immune Disorders (PID) This study focuses on genetic causes of severe immune disorders, also known as Primary ImmunoDeficiencies with the largest category being CVID, but it may also include the ... Steroid Resistant Nephrotic Syndrome (SRNS)

23 Feb 2024: Defects in the ability to mount effective B cell or T cell responses have been implicated in infectious susceptibility, impaired surveillance of cancer and immunodeficiencies, whereas a breakdown of immunological tolerance ... Transmission and evolution

23 Feb 2024: The department has an interest in innate immunity, B cell lineage and repertoire development; natural and vaccine induced immunity to streptococcus pneumonia in health and chronic disease. ... Anti-tumour necrosis factor-alpha therapy for severe

23 Feb 2024: Large genome-wide association study identifies three novel risk variants for restless legs syndrome. ... Whole-genome sequencing of a sporadic primary immunodeficiency cohort. Nature. 2020 Jul;583(7814):90-95.

23 Feb 2024: We called this newly identified disease Activated PI3K- δ Syndrome (APDS) after the enzyme in the immune system that is affected by the genetic mutation.”. ... Although the prevalence of the disease is not yet known, the scientists believe that it is

23 Feb 2024: During his research he took a leading role in the discovery of a novel cause of Primary Immunodeficiency called Activated PI3kinase Delta Syndrome, or APDS.

23 Feb 2024: Site Search. Study of rare monogenic immunodeficiency reveals population of B cells that exacerbate Streptococcal pneumoniae infection. ... School of Clinical Medicine. Featured Articles. Study of rare monogenic immunodeficiency reveals population of B

23 Feb 2024: Mutations in AP3D1 associated with immunodeficiency and seizures define a new type of Hermansky-Pudlak syndrome.

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38.</p> <p>Bigley V, Haniffa M, Doulatov S, Wang XN, Dickinson R, McGovern ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

23 Feb 2024: IRF8 mutations and human dendritic-cell immunodeficiency. N Engl J Med. 2011 Jul 14;365(2):127-38. ... The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency.

16 Feb 2024: An investigation of RF networks and RF mean levels/p pApril Le: Neurophysiological biomarkers of dementia in Down Syndrome/p pSharon Neufeld: Does mental health treatment promote family functioning to mitigate ... of change/p pLucie Aman: Markers of risk

23 Feb 2024: the process by which new variants likely arise, and also reporting the first data on Pfizer BioNTech vaccine-induced antibody responses against the B.1.1.7 ‘Kent UK’ variant. ... His research investigates the basis for pathological immune activation

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require

23 Feb 2024: JA, Lehner PJ (2014) TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. ... and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic study.<span>Lancet</span>.

16 Jan 2024: 2. Addition of addendum 14.0 to include a new NIHRBR-RD project, Paediatric bone marrow failure syndrome (SMD).

23 Feb 2024: Cambridge Cardiovascular - Wellcome Sanger Institute https://www.cardiovascular.cam.ac.uk/institutions/dir-sanger en Jack Palmer https://www.cardiovascular.cam.ac.uk/staff/jack-palmer <div class="field field-name-body field-type-text-with-summary

23 Feb 2024: Cambridge Immunology Network - Immunogenetics https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/immunogenetics The complex effects of genotype on phenotype in immunology Every immunologist makes use of genetics at some level but the

23 Feb 2024: www.ncbi.nlm.nih.gov/pubmed/29084722" rel="noopener noreferrer external" target="_blank">DNA damage induced by topoisomerase inhibitors activates SAMHD1 and blocks HIV-1 infection of ... blank">Simian Immunodeficiency Virus envelope glycoprotein

23 Feb 2024: Hapfelmeier, R.G. Jones, C. Hess. Memory CD8+ T Cells Require Increased Concentrations of Acetate Induced by Stress for Optimal Function. ... Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity.