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24 Aug 2022: In mammals, TEs and endogenous retroviruses have playedan important role in the evolution of the immune system, giving rise to enhancers regu-lating the expression of genes in response to interferon, ... Chuong, N. C. Elde, C. Feschotte, Regulatory

28 Feb 2023: Overexpression of wild-type transthyre-tin in the APP23 mouse model of AD reduced cognitive and motor impairments, whereas silencing of the endogenous transthyretin gene promoted neuropathology76. ... Inspired by this mechanism, endogenous internal-izing

28 Feb 2023: The endogenous proteins that are sequestered by the aggregates share distinct physicochemical properties: They are relatively large in size and significantly enriched in predicted unstructured regions, features that are strongly linked

2 Mar 2023: We tested human endogenous fat-soluble(red) and water-soluble (blue) vitamin metabolites in a ThT-basedscreen to identify vitamin metabolites that either accelerate or delaythe aggregation of Aβ42. ... Togetherwith the C. elegans experiments, these data

20 Mar 2023: Endogenous GRAF1a was found on lipid droplets in oleic-acid-fed primary glial cells.

13 Sep 2022: The Biogenesis of Multipass Membrane Proteins. Luka Smalinskait _e and Ramanujan S. Hegde. MRC Laboratory of Molecular Biology, Cambridge CB2 0QH, United Kingdom. Correspondence: rhegde@mrc-lmb.cam.ac.uk. Multipass membrane proteins contain two or

18 May 2022: Replisomes facing exogenous and endogenous stress, or replisome components that have become mutated, have also been identified as a characteristic of cancerous cells.

5 May 2022: Enzyme-catalyzed proximity labeling (PL) has emerged as a powerful and generalizable method to map the locations and interactions of endogenous proteins in the context of living cells, applicable to even

15 Sep 2022: Evolutionary History of Endogenous Human Herpesvirus 6 Reects Human Migration out of Africa (2021) Molecular Biology and Evolution, 38 (1), pp.

15 Sep 2022: Evolutionary History of Endogenous Human Herpesvirus 6 Reects Human Migration out of Africa (2021) Molecular Biology and Evolution, 38 (1), pp.