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Protein and Nucleic Acid Chemistry - MRC Laboratory of Molecular…
https://www2.mrc-lmb.cam.ac.uk/research/protein-and-nucleic-acid-chemistry/
20 May 2024:
Alan Fersht - Tumour suppressor p53 structure and drug discovery.
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spongistatin 1
https://www-jmg.ch.cam.ac.uk/data/molecules/polyketides/spongistatin.html6 May 2024: s66;P5;P57;P53;P52;P50;P24;N8;s3;s76;d76;N15;s79;N17;N29;N24;s82;s84;d84;/rC:-.3572,3.7125,0;-.3572,2.8875,0;1.0717,2. -
Scheres lab
https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html3 May 2024: Valle (2011) "Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA". -
Publications: Biology
www.tcm.phy.cam.ac.uk/~bds10/dir/publications_bio.html25 Apr 2024: Simons. doi:10.1016/j.stem.2010.05.017. Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia. -
Cancer and its microenvironment! From mechanisms to translation…
https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf30 Apr 2024: Ras) and tumour suppression proteins (e.g. p53, p16/p19ARF or p21) (for review see Hynds et al., 2022; Wang et al., 2022).
20 May 2024:
Alan Fersht - Tumour suppressor p53 structure and drug discovery.
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