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30 Apr 2024: In the short term, the scientific community will gain new information on the pathways and genes that we will investigate. ... Numbers are being adjusted in Dec 2022 following the obtention of new research funding.

30 Apr 2024: Our findings should guide these attempts and clarify the mechanisms of action these new therapies employ. ... When animals are exposed to new diets or environments they receive training sessions.

30 Apr 2024: relevant disease animal models to give us an extra layer of confidence in developing these new medications. ... In all new studies undertaken, the level of insult will be assessed before conducting further studies.

30 Apr 2024: Finally, full training will be provided to new technicians who are unfamiliar with these procedures. ... This will ensure that we maintain compliance should any new updates be posted.

30 Apr 2024: The treatments that are validated in the project may include new intellectual property. ... Altogether, these will generate a blueprint for clinical studies, which will bring successful new treatments to patients.

30 Apr 2024: Our plan is to publish research papers with new information on which human diseases involve programmed axon death and which specific people are most at risk. ... As we have shown, when a new 3Rs method becomes available (e.g., hiPSC-derived neurons), we

30 Apr 2024: Any new drug development can take up to 10-12 years before it can be used on human patients. ... We have developed a new method where we can screen antibody secreting B-cells directly for antigen binding.

30 Apr 2024: To the wider pharmaceutical industry and patients this could lead into the development of new anti-cancer therapies. ... Pilot studies are used to establish the correct dose of reagents/cells, timelines, and to generate baseline data for new experiments.

30 Apr 2024: To enable us to decide what doses of new treatments we need to use in our respiratory and immunology disease models. ... There are multiple stages of non-animal screening of new molecules that are in place before testing in rodent.

30 Apr 2024: This means that others do not need to generate new mutants or samples, minimising animal numbers. ... For any new procedures we will review published protocols from experienced collaborators before conducting any experiments.