Search

14 Aug 2023: http://haseloff.plantsci.cam.ac.uk (note: these pages are suitable for direct printing) Jim Haseloff, University of Cambridge.

14 Aug 2023: Biology will never be the same. The remarkable scientific success of biology in describing, explaining, and manipulating natural systems is so well recognized as to be a cliche—but the engineering application of that scientific knowledge is just

14 Aug 2023: Genomics, Epigenetics & Synthetic Biology. Part II Plant Sciences Module L1. Synthetic Biology: Prof. Jim Haseloff. Supplementary material:. Click here to find relevant papers as downloadable PDFs. Click here to find sample essay questions. Click

14 Aug 2023: Microscopy of GFP-expressing plant tissues. The major advantage of GFP is that it is intrinsically fluorescent, and the protein is be directly visible in living tissues where it is being expressed. There are many benefits to working with live samples

14 Aug 2023: Cambridge team for the iGEM2012 Synthetic Biology competition. Cambridge iGEM2012 team project. iGEM teams have characterised an array of biosensor components, but outputs are often inconsistent and, despite common assembly standards, it remains

14 Aug 2023: Macrophotography in the field. The documentation of liverworts in the field, growth room or laboratory can be a challenge. The small size of the plants means that plant features may need to be captured at sub-millimetre, almost cellular scales.

14 Aug 2023: The student team. Each year we recruit 6-12 undergraduate students to participate in the iGEM competition. The students work as an interdisciplinary team to construct an engineered biological system from DNA components, including design and

14 Aug 2023: Synthetic Biology Explained: Bridge8. Synthetic Biology: Overview - Victor de Lorenzo. Early Synthetic Biology talk: Tom Knight. E.O. Wilson: Synthetic Biology Will Radically Change the World. Jim Haseloff, University of Cambridge.

14 Aug 2023: Cambridge iGEM2011 Bactiridescence project. Inventive constructions using BioBricks. Bioluminescence and the science of Christmas. Glowing trees could light up city streets. How 'bioluminescent' trees that glow like fireflies could one day replace

14 Aug 2023: Plant and microbial microscopy and visualisation. The last twenty years have seen a revolution in the application of optical techniques to the study of biological systems. This largely due to the development of highly specific fluorescent labelling

14 Aug 2023: Plant Synthetic Biology. University of Cambridge, Plant Sciences Part II. Discuss the relative benefits and difficulties of genetically reprogramming metabolism in algae versus plants. Describe recent advances in the assembly of synthetic DNAs. What

14 Aug 2023: Plant Visions 1904-2004. An exhibition of images to celebrate the centenary of the opening of the Plant Sciences laboratories in 1904. Curated by Beverley Glover (website) and Jim Haseloff. Click here to view the exhibit. Download a copy of the

14 Aug 2023: 3D visualisation. Individual cells can be segmented using confocal datasets and rendered in three dimensions. Whole tissues can be reconstructed from the component cells - as shown here for a root meristem within an Arabidopsis embryo. Outer cells

14 Aug 2023: Abstract: Malaria is a global health problem that threatens 300-500 million people and kills more than one million people annually.

14 Aug 2023: Crystals, microbes and plants. Fernán Federici & Jim Haseloff. “What are the roots that clutch, what branches grow. Out of this stony rubbish?”. TS Eliot, The Waste Land. Part of a pioneering new exhibition, ‘April is the Cruellest Month.’

14 Aug 2023: Synthetic Genomics. A series of papers has been published in Science (10th March 2017), which provide a picture of current progress to resynthesise the entire genome of Saccharomyces cerevisiae - the SC2.0 project (). Four of these papers have been

14 Aug 2023: Vanguard Alta Pro 2+ 263AT with GH-100 pistol grip ball & socket head. For high resolution and/or time-lapse work with small plants like liverworts, a camera support is very useful…even essential. The camera support of course needs to be stable,

14 Aug 2023: Mk I Handheld Macroscope (Spring 2017). Original setup for high resolution handheld macrophotography. 1. Panasonic Lumix GX80 camera with 16 megapixel 4/3" sensor, image stabilisation, 4K video, focus bracketing and image stacking. 2. Neewer 10mm

14 Aug 2023: Weatherproof cameras for field documentation. Comparison of Olympus TG-4 and TG-5 cameras for handheld collection of extended focus macrographs. The TG-4 is an extremely robust point-and-shoot camera that can be equipped with an LED illuminator (LG-1

14 Aug 2023: The wild type Aequorea victoria green fluorescent protein mRNA is mis-spliced in Arabidopsis thaliana. GFP sequences were amplified from DNA or mRNA isolated from transgenic Arabidopsis thaliana C24 plantlets. Radiolabelled products were then mapped