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381 - 430 of 1,348 search results for p53

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  2. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/16
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  3. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/17
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  4. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/18
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  5. Katy Brown, PhD | Bioinformatics Training

    https://bioinfotraining.bio.cam.ac.uk/staff/katy-brown-phd
    27 Jul 2024: Contributors: Ingrida Olendraite; Katherine Brown; Andrew E. Firth. A novel map of human p53 response elements uncovers evidence of selection pressures and variants similar to Li-Fraumeni Syndrome mutations. ... Germline and Somatic Genetic Variants in

  6. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/19
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  7. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  8. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  9. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  10. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  11. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  12. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  13. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  14. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  15. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  16. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  17. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/30
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  18. Publications | Centre for Experimental Biophysical Chemistry

    https://www.ch.cam.ac.uk/biophyschem/publications?page=5
    26 Jul 2024: Nature neuroscience. (2022). 25,. 1582. (doi: 10.1038/s41593-022-01206-2). Characterization of full-length p53 aggregates and their kinetics of formation.

  19. Lucia Pinon P Giraldez | MRC Toxicology Unit

    https://www.mrc-tox.cam.ac.uk/staff/lucia-pinon-p-giraldez
    27 Jul 2024: Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane. ... Genomic instability in mutant p53 cancer cells upon entotic engulfment.

  20. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/31
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  21. Dr Mark Bycroft | Department of Pharmacology

    https://www.phar.cam.ac.uk/dr-mark-bycroft-0
    27 Jul 2024: I also study transcription factors that play a key role in cancer such as p53 and MYC.

  22. Publications | Wales Group

    https://www.ch.cam.ac.uk/group/wales/publications?page=14
    26 Jul 2024: J Chem Phys. (2009). 130,. 194508. (doi: 10.1063/1.3131690). Computer Simulations of Peptides from the p53 DNA Binding Domain.

  23. index.html

    https://www2.mrc-lmb.cam.ac.uk/groups/fersht/
    26 Jan 2021: Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... Tumour Suppressor p53. Structural Biology and Drug Discovery. Alan Fersht. MRC Laboratory of Molecular Biology.

  24. Publications | Clarke Group

    https://www.ch.cam.ac.uk/group/sclarke/publications?page=2
    26 Jul 2024: 1474. (doi: 10.1016/j.bpj.2020.09.007). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

  25. Publications | Centre for Atmospheric Science

    https://www.ch.cam.ac.uk/group/atm/publications?page=14
    26 Jul 2024: Weather. (2020). 75,. 353. (doi: 10.1002/wea.3795). A p53-Dependent Checkpoint Induced upon DNA Damage Alters Cell Fate during hiPSC Differentiation.

  26. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/109
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  27. SRI activities showcased at Science Hackday PDX | Engineering Biology …

    https://www.engbio.cam.ac.uk/news/sri-activities-showcased-pdx
    27 Jul 2024: Projects included an orca sound ocean simulator, numerous artistic projects such as a DNA helix light and programmed light installation displaying the p53 sequence, sensors, drones and more.

  28. Dr Vaithish Velazhahan | Gonville & Caius

    https://www.cai.cam.ac.uk/people/dr-vaithish-velazhahan
    26 Jul 2024: and Schrick, K., 2020. Dietary flavonoid fisetin binds human SUMO1 and blocks sumoylation of p53.

  29. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/110
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  30. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

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  31. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/98
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  32. Publications - Professor Bennett's Group

    https://www.med.cam.ac.uk/bennett/publications/
    23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Professor Bennett's Group. Publications. Links. 2024 University of Cambridge.

  33. Scheres lab

    https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html
    23 Jul 2024: Valle (2011) "Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA".

  34. Featured Articles Archives - Page 14 of 32 - School of Clinical…

    https://www.medschl.cam.ac.uk/category/feature/page/14/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  35. Spring Group - Research

    https://www-spring.ch.cam.ac.uk/research/peptides.shtml
    In the Spring group, our research has focused on the development of novel two-component peptide stapling methodologies and their application to biologically relevant targets (including MDM2/p53, CK2, BH3-proteins, ... TNKS). A few representative examples

  36. Graduate Poster Display | Pembroke

    https://www.pem.cam.ac.uk/college/news/graduate-poster-display
    26 Jul 2024: Chiba Ene (PhD Medical Sciences) - Histone demethylase Jumonji D3 (JMJD3) as a Tumor Suppressor by Regulating p53 Activity through Lysine Demethylation.

  37. School News Archives - Page 12 of 29 - School of Clinical Medicine

    https://www.medschl.cam.ac.uk/category/schoolnews/page/12/
    23 Feb 2024: Approximately half of lung adenocarcinomas, the most common type of lung cancer, harbor mutations in a gene called TP53(p53), a key player in the body’s in-built defence mechanism

  38. Dr Mattia Frontini | Cambridge Cardiovascular

    https://www.cardiovascular.cam.ac.uk/directory/mfrontini
    23 Feb 2024: Interaction between the Cockayne syndrome B and p53 proteins: implications for aging. ... CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination.

  39. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/99
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  40. Freeze Frame » tents

    https://www.freezeframe.ac.uk/tag/tents/page/19?x=x&slideshow=1
    full information on this image ». P53/43/545 (1931). Camp at foot of glacier.

  41. Freeze Frame » sledges

    https://www.freezeframe.ac.uk/tag/sledges/page/53?x=x&slideshow=1
    full information on this image ». P53/43/545 (1931). Camp at foot of glacier.

  42. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/pi/huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  43. Publications - Dr Rana's Group

    https://www.med.cam.ac.uk/rana/publications/
    23 Feb 2024: Quick Links. For staff. For alumni. For business. Colleges & departments. Libraries & facilities. Museums & collections. Email & phone search. Search site. Publications. Dr Rana's Group. Publications. 2024 University of Cambridge.

  44. Publications | Knowles Lab

    https://www-knowles.ch.cam.ac.uk/publications
    26 Jul 2024: Journal: Scientific Reports 12 (1). ------------------------------. Characterization of full-length p53 aggregates and their kinetics of formation.

  45. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/89
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  46. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/13
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  47. Genome-editing tool could increase cancer risk in cells, say…

    https://www.cam.ac.uk/research/news/genome-editing-tool-could-increase-cancer-risk-in-cells-say-researchers
    Thumbnail for Genome-editing tool could increase cancer risk in cells, say researchers | University of Cambridge 11 Jun 2018: Absence of p53 in cells makes them more likely to become tumorous as damage can no longer be corrected. ... The team found that by decreasing activity of p53 in a cell, they could more efficiently edit healthy cells.
    By: @cambridge_uni

  48. Research - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/research/
    23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

  49. Freeze Frame » sled_dogs

    https://www.freezeframe.ac.uk/tag/sled_dogs/page/73?x=x&slideshow=1
    full information on this image ». P53/43/545 (1931). Camp at foot of glacier.

  50. Freeze Frame » Photos: British Arctic Air Route Expedition 1930-31

    https://www.freezeframe.ac.uk/category/photos-british-arctic-air-route-expedition-1930-31/page/108
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  51. https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117

    https://www2.mrc-lmb.cam.ac.uk/wp-json/wp/v2/pages/117
    n. Cancer is a disease of mutation, and the most commonly mutated protein by far is the tumour suppressor p53. ... We discovered that about 30% of oncogenic mutants of p53 are just temperatures sensitive and can, in theory, be rescued by small molecules.

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