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Generation and screening of companion animal therapeutics.…
https://www.ubs.admin.cam.ac.uk/system/files/public/generation_and_screening_of_companion_animal_therapeutics._non-technical_summary_redacted.pdf30 Apr 2024: rodent models to test how well they remain detectable and/or functional over a defined period of time. ... The information gathered here will inform us which drug is best suited to take forward to test in the target animal species. -
Epigenetic inheritence and the control of developmental and…
https://www.ubs.admin.cam.ac.uk/system/files/public/epigenetic_inheritance_and_the_control_of_developmental_and_physiological_processes_non-technical_s_redacted.pdf30 Apr 2024: Typically, a mouse will experience each of these above procedures. Some animals will undergo 1, 2 or sometimes 3 behavioural tests typically to test motor skills, anxiety and spatial navigation. ... 3. Methods (test substances, quarantine and monitoring, -
Models of mitochondrial diseases, pathogenesis and therapy
https://www.ubs.admin.cam.ac.uk/system/files/public/models_of_mitochondrial_diseases_pathogenesis_and_therapy_non-technical_summary_redacted.pdf30 Apr 2024: The knowledge gained will be used to develop and test of novel therapeutic interventions. ... Live animals are required to test in vivo therapies. Wherever possible, animals will be killed prior to tissue harvest. -
Gut hormone modulation of metabolism (non-technical summary)_Redacted
https://www.ubs.admin.cam.ac.uk/system/files/public/gut_hormone_modulation_of_metabolism_non-technical_summary_redacted.pdf30 Apr 2024: Typically such tests will be performed whilst agents that modify gut hormone release or act on gut hormone receptors are also administered, typically directly into the blood stream or into the ... Metabolic fitness test like these will typically involve -
The development of in vivo expressed biologics as a platform for…
https://www.ubs.admin.cam.ac.uk/system/files/public/the_development_of_in_vivo_expressed_biologics_as_a_platform_for_novel_therapeutic_agents_non-techn_redacted.pdf30 Apr 2024: This work will make extensive use of pilot studies, as most of the test substances will be by definition novel, as they concern novel technologies or modalities (method of treatment). ... Pilot or tolerability studies will be carried out for new models -
Development of humanised mouse models for study of cancer…
https://www.ubs.admin.cam.ac.uk/system/files/public/development_of_humanised_mouse_models_for_study_of_cancer_immunotherapy_non-technical_summary_redacted.pdf29 Apr 2024: What's the aim of this project? The aim of this project is to study how the immune system recognises cancer cells, and test the safety and effectiveness of drugs that ... The proposed project will allow a better understanding of how the immune system -
Seminar 22 May 2024
https://www.clarehall.cam.ac.uk/wp-content/uploads/2024/05/Seminar-22-May-2024.pdf16 May 2024: ordained activities." Every three years Shun held an examination of merit, after three such tests, officers were demoted or advanced. -
Vaccine development and fundamental reseach on viruses of medical…
https://www.ubs.admin.cam.ac.uk/system/files/public/vaccine_development_and_fundamental_research_on_viruses_of_medical_importance_non-technical_summary_redacted.pdf29 Apr 2024: We primarily use adult female mice, hamsters and guinea pigs to test our vaccines. ... There exists no cell-based model or less sentient model to test vaccines. -
1ACP R&T Guidance Academic Career Pathways 2024 (Research &…
https://www.acp.hr.admin.cam.ac.uk/files/acp_rt_guidance_v1.4_-_september_2023.pdf13 Jun 2024: 1ACP R&T Guidance. Academic. Career Pathways 2024. (Research & Teaching). Guidance and Procedure. 2023-2024. V1.4/September 2023. 2 ACP R&T Guidance. Contents. Introduction 4. Overview 5. Key Principles 6. Academic Career Pathways R&T Timetable 7. -
1 CLARE COLLEGE CHAPEL Pew Booklet Easter Term 2024 ...
https://www.clare.cam.ac.uk/sites/default/files/2024-04/FINAL%20Easter%20Term%202024%20Pew%20Booklet.pdf16 Apr 2024: Then you will be able to test and approve what God’s will is – his good, pleasing and perfect will. -
New treatments for renal and liver disease (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/new_treatments_for_renal_and_liver_disease_non-technical_summary_redacted.pdf30 Apr 2024: Renal function can be assessed by tests performed in urine or blood collected from the animals. ... For example we use human kidney organoids to test drug activity in certain projects. -
Breeding and maintenance of rodents for drug discovery platform
https://www.ubs.admin.cam.ac.uk/system/files/public/breeding_and_maintenance_of_rodents_for_drug_discovery_platform_non-technical_summary_redacted.pdf29 Apr 2024: A small subset of mice will undergo a blood test to check how much of a certain marker of interest they have (for example, a protein). ... The best, non-invasive way to monitor disease progression is to test the urine for protein. -
Interventions in pregnancy effects of obesity on maternal and…
https://www.ubs.admin.cam.ac.uk/system/files/public/interventions_in_pregnancy_effects_of_obesity_on_maternal_and_offspring_health_non-technical_summa_redacted.pdf30 Apr 2024: After this she may undergo a glucose tolerance test (as described in point 5) prior to her being humanely killed and her tissues collected and stored for laboratory analyses. ... c) Glucose or insulin tolerance tests which require injection of either -
2024-05-22 Council Minutes Unreserved Business
https://www.sid.cam.ac.uk/sites/default/files/2024-05-22%20Council%20Minutes%20Unreserved%20Business%20%28Approved%29_0.pdf14 Jun 2024: Archaeology) Year 2: Literary Studies (incl. English, Modern & Medieval Languages, Classics; etc) Year 3: Law, Politics & International Relations, Economics, Land Economy &. Management Year 4: Anthropology, Architecture, Divinity, -
Mechanisms of organ development and disease (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/mechanisms_of_organ_development_and_disease_non-technical_summary_redacted.pdf30 Apr 2024: This will allow us to change the signalling within particular cells and test the consequences on the mechanics and development of the whole organ. ... Why were they not suitable? It is not possible to entirely replace animal experiments for this project -
Equality and Diversity Information Report 2022-23 of the University…
https://www.reporter.admin.cam.ac.uk/reporter/2023-24/weekly/6736/EDI-Report-2023.pdf17 Apr 2024: for European Economic Area (EEA) staff. 58.2% of those from other non-UK nationalities were. -
COLLEGE ORDINANCES 2018 COLLEGE ORDINANCES 2018 COLLEGE ORDINANCES…
https://www.sid.cam.ac.uk/sites/default/files/ORDINANCES%202018_v14%20with%20hyperlinks.pdf27 May 2024: COLLEGE ORDINANCES 2018. COLLEGE ORDINANCES 2018. COLLEGE ORDINANCES 2018. This set of Ordinances were approved by Governing Body on 23 May 2018 pursuant to the Statutes being approved by Privy Council on 8 February 2018. Where there have been -
Metabolic basis of microglia function in development (non-technical…
https://www.ubs.admin.cam.ac.uk/system/files/public/metabolic_basis_of_microglia_function_in_development_non-technical_summary_redacted.pdf30 Apr 2024: This will create new opportunities to test new therapies that can stop inflammation, brain damage, and the subsequent development of neuropsychiatric disorders in the offspring. ... This has allowed us to test whether treatments will be (1) safe for -
Cartilage repair and replacement
https://www.ubs.admin.cam.ac.uk/system/files/public/cartilage_repair_and_replacement_non-technical_summary_redacted.pdf29 Apr 2024: 4 or less). Followed by longer (e.g. 3, 6, 12 or 24 months), larger studies (less than 10 animals per test group at each time point). -
Profiling of test agents in rodents in a drug discovery platform
https://www.ubs.admin.cam.ac.uk/system/files/public/profiling_of_test_agents_in_rodents_in_a_drug_discovery_platform_non-technical_summary_redacted.pdf30 Apr 2024: We will also study how the test agent distributes itself around the body. ... Dosing will usually be daily, but this may vary depending upon the test agent.
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