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  2. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/brian-huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead
  3. Publications - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/publications/
    23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.
  4. Professor Margaret Ashcroft | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft
    23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell
  5. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=300
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  6. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    24 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and
  7. https://www.pdn.cam.ac.uk/taxonomy/term/58/feed

    https://www.pdn.cam.ac.uk/taxonomy/term/58/feed
    25 Jul 2024: b>. Mutations in the murine homologue of TUBB5 cause microcephaly by perturbing cell cycle progression and inducing p53-associated apoptosis.
  8. Professor Alan Warren | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/warren
    23 Feb 2024: consequence of p53 stabilization in response to ribosomal stress.
  9. CDD-MRC Conference on “Genes vs Environment in Cancer” | MRC…

    https://www.mrc-tox.cam.ac.uk/news/cdd-mrc-conference-genes-vs-environment-cancer
    25 Jul 2024: p53 in the response to environmental stressors.
  10. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=311
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  11. George Eric Fairbairn, 2nd Lieutenant, 10th Durham Light Infantry |…

    https://www.jesus.cam.ac.uk/george-eric-fairbairn-2nd-lieutenant-10th-durham-light-infantry
    Thumbnail for George Eric Fairbairn, 2nd Lieutenant, 10th Durham Light Infantry | Jesus College in the University of Cambridge 24 Jul 2024: He hates collars, takes no milk in his tea through fear of dead flies, and is a confirmed Peripatetic after bump-suppers” (Chanticlere, Lent Term 1909, p53 and p37 respectively).
  12. CBSB - Tissue bank and blood collection in Cambridge

    https://www.haem.cam.ac.uk/cambridge-blood-and-stem-cell-biobank/
    23 Feb 2024: Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.
  13. Part II Exam Questions Reports 2018/19 (incomplete) Paper 1 ...

    https://www.ch.cam.ac.uk/teaching/files/Examiners%20Reports/Part%20II_ExamReports%20_2018-19.pdf
    9 Jul 2024: The best students got this correct. Many students also thought the protein, p53 had disulphide bridges. ... p53 was covered in the lectures as a nuclear protein that bound DNA so they should have been aware it is in a reducing environment.
  14. Catherine Perry - Department of Public Health and Primary Care

    https://www.phpc.cam.ac.uk/people/ceu-group/ceu-research-staff/catherine-perry/
    23 Feb 2024: P53 Epidemiological evidence to support a tax on Sugar Sweetened Drinks as a measure to address childhood obesity.
  15. Cytosponge biomarker panel used to prioritise endoscopic…

    https://www.oncology.cam.ac.uk/news/cytosponge-biomarker-panel-used-prioritise-endoscopic-barretts-oesophagus-surveillance
    23 Feb 2024: Published in The Lancet Oncology, researchers evaluated the role of the Cytosponge atypia, p53 overexpression, and clinical risk factors (age, sex, and segment length) to prioritise patients for endoscopy.
  16. Dr Rémi B. Fiancette | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/fiancette
    23 Feb 2024: and Denizot Y., 2012, Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. ... Magnone V., Cogné M. and Denizot Y., 2011, A p53 defect sensitizes
  17. https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/26

    https://www.med.cam.ac.uk/bennett/wp-json/wp/v2/pages/26
    23 Feb 2024: {"id":26,"date":"2011-03-01T14:00:13","date_gmt":"2011-03-01T14:00:13","guid":{"rendered":"http://www.med.cam.ac.uk/infectious-diseases/?page_id=26"},"modified":"2015-02-06T11:14:05","modified_gmt":"2015-02-06T11:14:05","slug":"publications","status"
  18. Greta Skrupskelyte | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/great-skrupskelyte
    23 Feb 2024: 2018) Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
  19. Dr Ingo Ringshausen - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/dr-ingo-ringshausen/
    23 Feb 2024: Swigart, and G.I. Evan. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Finch, L.B. Swigart, and G.I. Evan. Thepathological response to DNA damage does not contribute to p53-mediated tumour suppression.
  20. Jason William Chin Page 1 of 18 MRC Laboratory ...

    https://www2.mrc-lmb.cam.ac.uk/ccsb/wp-content/uploads/2024/01/Chin-cv-26012024.pdf
    29 Jan 2024: Chin, W. Fischle, S.M. Gasser. EMBO J. 2011. 30: 2610-2621. (53) Acetylation of Lysine 120 of p53 endows DNA-binding Specificity at Effective Physiological Salt Concentration.
  21. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=67
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  22. https://www.phar.cam.ac.uk/taxonomy/term/5/feed

    https://www.phar.cam.ac.uk/taxonomy/term/5/feed
    25 Jul 2024: Department of Pharmacology - Academic Staff https://www.phar.cam.ac.uk/directory/academicstaff An A-Z directory of all Department members can be found here. The Department provides contact details for all members of the Department. Please follow the
  23. Dr Pentao Liu | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk
    23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some
  24. Computational modelling of cancer and aging | Department of Genetics

    https://www.gen.cam.ac.uk/research/research-groups/computational-modelling-cancer-and-aging
    25 Jul 2024: Simulations reveal that different responses to cell crowding determine the expansion of p53 and Notch mutant clones in squamous epithelia.
  25. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=329
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  26. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=348
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  27. https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6

    https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6
    23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.
  28. The economy isn’t working - for people or the planet. It's time…

    https://www.cisl.cam.ac.uk/news/blog/economy-isnt-working-people-or-planet-its-time-new-narrative
    22 Jul 2024: xxii] T. Jackson, Post Growth Life after Capitalism, (polity, 2021) p53.
  29. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=210
    24 Jul 2024: Diarylethene moiety as an enthalpy-entropy switch: photoisomerizable stapled peptides for modulating p53/MDM2 interaction.
  30. Dr Nunzio Iraci | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/dr-nunzio-iraci
    23 Feb 2024: p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma. Cancer Res.
  31. https://www.cardiovascular.cam.ac.uk/taxonomy/term/8/feed

    https://www.cardiovascular.cam.ac.uk/taxonomy/term/8/feed
    23 Feb 2024: Cambridge Cardiovascular - Functional Genomics https://www.cardiovascular.cam.ac.uk/directory/research-themes/functional-genomics Functional Genomics theme led by Prof Nicole Soranzo performs epigenomic annotation of cells relevant to the
  32. Dr El Kahina Meziane | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/ekm29%40cam.ac.uk
    23 Feb 2024: Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.
  33. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=172
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  34. Cancer and its microenvironment! From mechanisms to translation…

    https://www.ubs.admin.cam.ac.uk/system/files/public/cancer_and_its_microenvironment_from_mechanisms_to_translation_non-technical_summary_redacted.pdf
    30 Apr 2024: Ras) and tumour suppression proteins (e.g. p53, p16/p19ARF or p21) (for review see Hynds et al., 2022; Wang et al., 2022).
  35. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=392
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  36. https://bioinfotraining.bio.cam.ac.uk/taxonomy/term/631/feed

    https://bioinfotraining.bio.cam.ac.uk/taxonomy/term/631/feed
    12 Jul 2024: Firth</div> </div> </div> <hr /></div> <h4 class="work-title orc-font-body ng-star-inserted" header="">A novel map of human p53 response elements uncovers evidence of selection pressures and ... 084X </a></div> </div> </div> <hr /></div> <h4
  37. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=399
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  38. https://bioinfotraining.bio.cam.ac.uk/taxonomy/term/691/feed

    https://bioinfotraining.bio.cam.ac.uk/taxonomy/term/691/feed
    12 Jul 2024: Bioinformatics Training - Cholera Genomics https://bioinfotraining.bio.cam.ac.uk/subjects/cholera-genomics Cholera Genomics en Sebastian Bruchmann, PhD https://bioinfotraining.bio.cam.ac.uk/staff/sebastian-bruchmann-phd <div class="field
  39. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=208
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  40. https://www.med.cam.ac.uk/kaser/wp-json/wp/v2/pages/26

    https://www.med.cam.ac.uk/kaser/wp-json/wp/v2/pages/26
    23 Feb 2024: P, Aden K.u00a0/spanEpithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.u00a0span class="docsum-journal-citation
  41. Dr Andrew McKenzie | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/anm%40mrc-lmb.cam.ac.uk
    23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q. –.
  42. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=354
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  43. https://www.immunology.cam.ac.uk/taxonomy/term/77/feed

    https://www.immunology.cam.ac.uk/taxonomy/term/77/feed
    23 Feb 2024: Tweddle DA.<br /> p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma.<br /> Cancer Res.
  44. Autophagy-mediated apoptosis eliminates chromosomally abnormal cells…

    https://www.trophoblast.cam.ac.uk/news/autophagy-mediated-apoptosis-eliminates-chromosomally-abnormal-cells-from-the-mouse-epiblast
    25 Jul 2024: This stress in turn activates a catabolic process, known as autophagy that leads to the death of the abnormal cells in a p53-dependent process. ... Future studies in higher mammalian species are however required to reveal if p53-dependent autophagy and
  45. Publications: Biology

    www.tcm.phy.cam.ac.uk/~bds10/dir/publications_bio.html
    15 Jun 2024: Simons. doi:10.1016/j.stem.2010.05.017. Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia.
  46. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=222
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  47. Professor Alan J Warren - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/professor-alan-j-warren/
    23 Feb 2024: A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.
  48. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=356
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  49. https://www.immunology.cam.ac.uk/taxonomy/term/57/feed

    https://www.immunology.cam.ac.uk/taxonomy/term/57/feed
    23 Feb 2024: Cambridge Immunology Network - Department of Medicine https://www.immunology.cam.ac.uk/departments/medicine en Professor Ravindra Gupta https://www.immunology.cam.ac.uk/staff/professor-ravindra-gupta <div class="field field-name-field-sd-consultancy
  50. Search Publications | Publications

    https://publications.ch.cam.ac.uk/publications-search?page=231
    24 Jul 2024: Search site. Publications. Uploading Images. Members of the Department can attach an image to a publication by clicking on the title of the publication in the listing below. Please note: all images attached to a publication will be visible on
  51. https://www.immunology.cam.ac.uk/taxonomy/term/7/feed

    https://www.immunology.cam.ac.uk/taxonomy/term/7/feed
    23 Feb 2024: Cambridge Immunology Network - Autoimmunity and inflammation https://www.immunology.cam.ac.uk/Networkdirectory/research-themes/autoimmunity-inflammation Investigating the causes of excessive and aberrant immune responses which result in inflammation

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