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21 - 40 of 54 search results for p53

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  2. Professor Alan Warren | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/people/affiliates/warren
    23 Feb 2024: consequence of p53 stabilization in response to ribosomal stress.

  3. Dr Suzanne Dawn Turner | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/sdturner
    23 Feb 2024: 2009) NPM-ALK modulates the p53 tumour suppressor pathway in a JNK and PI 3-Kinase dependent manner: MDM-2 is a potential therapeutic target for the treatment of ALK-expressing ... Merkel, O., Morrigl, R.,Turner, S.D. and Kenner, L. (2017) When the

  4. Scheres lab

    https://www2.mrc-lmb.cam.ac.uk/groups/scheres/publications.html
    3 May 2024: Valle (2011) "Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA".

  5. spongistatin 1

    https://www-jmg.ch.cam.ac.uk/data/molecules/polyketides/spongistatin.html
    6 May 2024: s66;P5;P57;P53;P52;P50;P24;N8;s3;s76;d76;N15;s79;N17;N29;N24;s82;s84;d84;/rC:-.3572,3.7125,0;-.3572,2.8875,0;1.0717,2.

  6. Dr Ingo Ringshausen - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/dr-ingo-ringshausen/
    23 Feb 2024: Swigart, and G.I. Evan. Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. ... Finch, L.B. Swigart, and G.I. Evan. Thepathological response to DNA damage does not contribute to p53-mediated tumour suppression.

  7. Professor Brian Huntly | Wellcome-MRC Cambridge Stem Cell Institute

    https://www.stemcells.cam.ac.uk/directory/brian-huntly
    23 Feb 2024: In association with an alteration of the DNA damage response mediated through suboptimal Crebbp acetylation of p53, DNA double strand breaks accumulate and accompanied by a relative decrease in apoptosis, lead

  8. Dr Pentao Liu | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/pl2%40sanger.ac.uk
    23 Feb 2024: By contrast, overactivity of Bcl11a is known to cause lymphomas. One member of the Bcl11a network is p53, known to be important in controlling cell division and, when mutated, important in ... If p53 also is inactivated in mice that lack Bcl11a, some

  9. Professor Margaret Ashcroft | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/margaretashcroft
    23 Feb 2024: Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1. ... Small-molecule activation of p53 blocks hypoxia-inducible factor 1alpha and vascular endothelial growth factor expression in vivo and leads to tumor cell

  10. Publications - Professor Marciniak's Group

    https://www.med.cam.ac.uk/marciniak/publications/
    23 Feb 2024: p53 and translation attenuation regulate distinct cell cycle checkpoints during endoplasmic reticulum (ER) stress.

  11. CBSB - Tissue bank and blood collection in Cambridge

    https://www.haem.cam.ac.uk/cambridge-blood-and-stem-cell-biobank/
    23 Feb 2024: Persistent STAT5 activation in myeloid neoplasms recruits p53 into gene regulation.

  12. Catherine Perry - Department of Public Health and Primary Care

    https://www.phpc.cam.ac.uk/people/ceu-group/ceu-research-staff/catherine-perry/
    23 Feb 2024: P53 Epidemiological evidence to support a tax on Sugar Sweetened Drinks as a measure to address childhood obesity.

  13. Dr Rémi B. Fiancette | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/fiancette
    23 Feb 2024: and Denizot Y., 2012, Mantle cell lymphoma-like lymphomas in c-myc-3'RR/p53+/- mice and c-myc-3'RR/Cdk4R24C mice: differential oncogenic mechanisms but similar cellular origin. ... Magnone V., Cogné M. and Denizot Y., 2011, A p53 defect sensitizes

  14. https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6

    https://www.med.cam.ac.uk/marciniak/wp-json/wp/v2/pages/6
    23 Feb 2024: Marciniak. 2013. p53 and Translation Attenuation Regulate Distinct Cell Cycle Checkpoints during Endoplasmic Reticulum (ER) Stress.

  15. Dr El Kahina Meziane | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/ekm29%40cam.ac.uk
    23 Feb 2024: Expression of Fbxo7 in haematopoietic progenitor cells cooperates with p53 loss to promote lymphomagenesis.

  16. Publications: Biology

    www.tcm.phy.cam.ac.uk/~bds10/dir/publications_bio.html
    15 Jun 2024: Simons. doi:10.1016/j.stem.2010.05.017. Stochastic fate of p53-mutant epidermal progenitor cells is tilted toward proliferation by UV B during preneoplasia.

  17. https://www.cardiovascular.cam.ac.uk/taxonomy/term/8/feed

    https://www.cardiovascular.cam.ac.uk/taxonomy/term/8/feed
    23 Feb 2024: Cambridge Cardiovascular - Functional Genomics https://www.cardiovascular.cam.ac.uk/directory/research-themes/functional-genomics Functional Genomics theme led by Prof Nicole Soranzo performs epigenomic annotation of cells relevant to the

  18. Dr Nunzio Iraci | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/dr-nunzio-iraci
    23 Feb 2024: p53 is a Direct Transcriptional Target of MYCN in Neuroblastoma. Cancer Res.

  19. Professor Alan J Warren - Department of Haematology

    https://www.haem.cam.ac.uk/staff/senior-staff/professor-alan-j-warren/
    23 Feb 2024: A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.

  20. Dr Andrew McKenzie | Cambridge Immunology Network

    https://www.immunology.cam.ac.uk/Networkdirectory/anm%40mrc-lmb.cam.ac.uk
    23 Feb 2024: and McKenzie, A.N.J. A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q. –.

  21. https://www.med.cam.ac.uk/kaser/wp-json/wp/v2/pages/26

    https://www.med.cam.ac.uk/kaser/wp-json/wp/v2/pages/26
    23 Feb 2024: P, Aden K.u00a0/spanEpithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal Carcinogenesis.u00a0span class="docsum-journal-citation

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